Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PTPRVP
  • Mouse genes Ptprv
  • Rat genes Ptprv
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ptprv

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	Ptprv	IMP		Rat	PMID:7527035|RGD:632779
Biological Process	GO:0046849	bone remodeling	Ptprv	IEP		Rat	PMID:7527035|RGD:632779
Biological Process	GO:0044242	cellular lipid catabolic process	Ptprv	IMP	MGI:MGI:3039948	Mouse	PMID:17693256
Biological Process	GO:0071320	cellular response to cAMP	Ptprv	IEP		Rat	PMID:7527035|RGD:632779
Biological Process	GO:0071320	cellular response to cAMP	Ptprv	IEP		Rat	PMID:8603605|RGD:151665808
Biological Process	GO:0071364	cellular response to epidermal growth factor stimulus	Ptprv	IEP		Rat	PMID:8603605|RGD:151665808
Biological Process	GO:0032869	cellular response to insulin stimulus	Ptprv	IMP	MGI:MGI:3039948	Mouse	PMID:17693256
Biological Process	GO:0071374	cellular response to parathyroid hormone stimulus	Ptprv	IEP		Rat	PMID:7527035|RGD:632779
Biological Process	GO:0071374	cellular response to parathyroid hormone stimulus	Ptprv	IEP		Rat	PMID:8603605|RGD:151665808
Biological Process	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	Ptprv	IGI	MGI:MGI:98834	Mouse	PMID:16107883
Biological Process	GO:0048144	fibroblast proliferation	Ptprv	IGI	MGI:MGI:98834	Mouse	PMID:16107883
Biological Process	GO:0048144	fibroblast proliferation	Ptprv	IMP	MGI:MGI:3039948	Mouse	PMID:16107883
Biological Process	GO:0042593	glucose homeostasis	Ptprv	IMP	MGI:MGI:3039948	Mouse	PMID:17693256
Biological Process	GO:0031571	mitotic G1 DNA damage checkpoint signaling	Ptprv	IMP	MGI:MGI:3039948	Mouse	PMID:16107883
Biological Process	GO:0048147	negative regulation of fibroblast proliferation	Ptprv	IGI	MGI:MGI:98834	Mouse	PMID:16107883
Biological Process	GO:0048147	negative regulation of fibroblast proliferation	Ptprv	IMP	MGI:MGI:3039948	Mouse	PMID:16107883
Biological Process	GO:0046676	negative regulation of insulin secretion	Ptprv	IMP	MGI:MGI:3039948	Mouse	PMID:17693256
Biological Process	GO:0036035	osteoclast development	Ptprv	IEP		Rat	PMID:7527035|RGD:632779
Biological Process	GO:0031016	pancreas development	Ptprv	IMP	MGI:MGI:3039948	Mouse	PMID:17693256
Biological Process	GO:0035335	peptidyl-tyrosine dephosphorylation	Ptprv	IMP		Rat	PMID:7527035|RGD:632779
Biological Process	GO:0018214	protein carboxylation	Ptprv	IMP	MGI:MGI:3039948	Mouse	PMID:17693256
Biological Process	GO:0007283	spermatogenesis	Ptprv	IEP		Rat	PMID:7527035|RGD:632779
Biological Process	GO:0044342	type B pancreatic cell proliferation	Ptprv	IMP	MGI:MGI:3039948	Mouse	PMID:17693256

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern