Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Ptprz1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes PTPRZ1
- Mouse genes Ptprz1
- Rat genes Ptprz1
- Zfish genes ptprz1a,ptprz1b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ptprz1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0017134	fibroblast growth factor binding	Ptprz1	IPI	RGD:70822	Rat	PMID:9705269\|RGD:9589122
Molecular Function	GO:0005178	integrin binding	PTPRZ1	IDA		Human	PMID:19141530
Molecular Function	GO:0016791	phosphatase activity	Ptprz1	IDA		Rat	PMID:17646177\|RGD:9590121
Molecular Function	GO:0016791	phosphatase activity	Ptprz1	IMP		Rat	PMID:30667096\|RGD:14397553
Molecular Function	GO:0005515	protein binding	PTPRZ1	IPI	UniProtKB:P21246	Human	PMID:10706604
Molecular Function	GO:0005515	protein binding	PTPRZ1	IPI	UniProtKB:P21246,UniProtKB:P35222	Human	PMID:10706604
Molecular Function	GO:0005515	protein binding	PTPRZ1	IPI	UniProtKB:P35222	Human	PMID:10706604
Molecular Function	GO:0005515	protein binding	PTPRZ1	IPI	UniProtKB:Q9UM73	Human	PMID:17681947
Molecular Function	GO:0005515	protein binding	PTPRZ1	IPI	UniProtKB:P21246	Human	PMID:19141530
Molecular Function	GO:0005515	protein binding	PTPRZ1	IPI	UniProtKB:Q12860	Human	PMID:21969550
Molecular Function	GO:0005515	protein binding	Ptprz1	IPI	PR:P12960	Mouse	PMID:12700241
Molecular Function	GO:0005515	protein binding	Ptprz1	IPI	PR:P11627	Mouse	PMID:12700241
Molecular Function	GO:0005515	protein binding	Ptprz1	IPI	UniProtKB:P21741	Rat	PMID:10212223\|RGD:14397575
Molecular Function	GO:0005515	protein binding	Ptprz1	IPI	RGD:621300	Rat	PMID:11520897\|RGD:9590114
Molecular Function	GO:0005515	protein binding	Ptprz1	IPI	UniProtKB:O88572	Rat	PMID:15466886\|RGD:14397578
Molecular Function	GO:0005515	protein binding	Ptprz1	IPI	UniProtKB:O88572,UniProtKB:P23229	Rat	PMID:15466886\|RGD:14397578
Molecular Function	GO:0005515	protein binding	Ptprz1	IPI	UniProtKB:P05556	Rat	PMID:15466886\|RGD:14397578
Molecular Function	GO:0005515	protein binding	Ptprz1	IPI	UniProtKB:P13612	Rat	PMID:15466886\|RGD:14397578
Molecular Function	GO:0005515	protein binding	Ptprz1	IPI	UniProtKB:P23229	Rat	PMID:15466886\|RGD:14397578
Molecular Function	GO:0005515	protein binding	Ptprz1	IPI	UniProtKB:Q5DTU0	Rat	PMID:30667096\|RGD:14397553
Molecular Function	GO:0005515	protein binding	Ptprz1	IPI	RGD:3444	Rat	PMID:8702927\|RGD:9589111
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	PTPRZ1	IDA		Human	PMID:10706604
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	Ptprz1	IMP		Mouse	MGI:MGI:3622611\|PMID:16513268
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	Ptprz1	IDA		Rat	PMID:11381105\|RGD:9589125
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	Ptprz1	IDA		Rat	PMID:16814777\|RGD:11344935
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	Ptprz1	IDA		Rat	PMID:21890632\|RGD:9590130
Cellular Component	GO:0030424	axon	Ptprz1	IDA		Rat	PMID:15708477\|RGD:9589113
Cellular Component	GO:0005737	cytoplasm	Ptprz1	IDA		Rat	PMID:15708477\|RGD:9589113
Cellular Component	GO:0030425	dendrite	Ptprz1	IDA		Rat	PMID:15708477\|RGD:9589113
Cellular Component	GO:0043197	dendritic spine	Ptprz1	IDA		Rat	PMID:15982644\|RGD:9590117
Cellular Component	GO:0031012	extracellular matrix	Ptprz1	IDA		Mouse	PMID:19141078
Cellular Component	GO:0005615	extracellular space	Ptprz1	IDA		Rat	PMID:15708477\|RGD:9589113
Cellular Component	GO:0030175	filopodium	Ptprz1	IDA		Rat	PMID:9660874\|RGD:9589123
Cellular Component	GO:0098978	glutamatergic synapse	Ptprz1	IDA		Rat	PMID:15982644\|RGD:9590117
Cellular Component	GO:0030426	growth cone	Ptprz1	IDA		Rat	PMID:8702927\|RGD:9589111
Cellular Component	GO:0030027	lamellipodium	Ptprz1	IDA		Rat	PMID:9660874\|RGD:9589123
Cellular Component	GO:0016020	membrane	Ptprz1	IDA		Rat	PMID:15708477\|RGD:9589113
Cellular Component	GO:0043025	neuronal cell body	Ptprz1	IDA		Rat	PMID:8702927\|RGD:9589111
Cellular Component	GO:0072534	perineuronal net	Ptprz1	IDA		Mouse	PMID:10793198
Cellular Component	GO:0072534	perineuronal net	Ptprz1	IDA		Rat	PMID:16644727\|RGD:9589827
Cellular Component	GO:0005886	plasma membrane	PTPRZ1	IDA		Human	PMID:19141530
Cellular Component	GO:0005886	plasma membrane	Ptprz1	IDA		Mouse	MGI:MGI:5805301\|PMID:27445335
Cellular Component	GO:0005886	plasma membrane	Ptprz1	IDA		Rat	PMID:16814777\|RGD:11344935
Cellular Component	GO:0098839	postsynaptic density membrane	Ptprz1	IDA		Rat	PMID:15982644\|RGD:9590117
Cellular Component	GO:0045211	postsynaptic membrane	Ptprz1	IDA		Rat	PMID:15982644\|RGD:9590117
Cellular Component	GO:0032587	ruffle membrane	Ptprz1	IDA		Rat	PMID:11381105\|RGD:9589125
Cellular Component	GO:0045202	synapse	Ptprz1	IDA		Mouse	PMID:16452087
Cellular Component	GO:0045202	synapse	Ptprz1	EXP		Mouse	PMID:16452087
Biological Process	GO:0007413	axonal fasciculation	Ptprz1	IDA		Rat	PMID:16150606\|RGD:9590115
Biological Process	GO:0007409	axonogenesis	Ptprz1	IDA		Mouse	PMID:10234020
Biological Process	GO:0007420	brain development	Ptprz1	IEP		Rat	PMID:9538229\|RGD:9589115
Biological Process	GO:0002244	hematopoietic progenitor cell differentiation	Ptprz1	IMP		Mouse	PMID:24029230
Biological Process	GO:0021766	hippocampus development	Ptprz1	IEP		Rat	PMID:10906718\|RGD:9589828
Biological Process	GO:0007611	learning or memory	Ptprz1	IMP		Mouse	MGI:MGI:3622611\|PMID:16513268
Biological Process	GO:0008285	negative regulation of cell population proliferation	Ptprz1	IMP		Rat	PMID:9809586\|RGD:9590125
Biological Process	GO:0010812	negative regulation of cell-substrate adhesion	Ptprz1	IDA		Rat	PMID:12821372\|RGD:9589826
Biological Process	GO:2000171	negative regulation of dendrite development	Ptprz1	IDA		Rat	PMID:11431463\|RGD:9589116
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	Ptprz1	IDA		Mouse	MGI:MGI:6294380\|PMID:12573468
Biological Process	GO:0048666	neuron development	Ptprz1	IEP		Rat	PMID:15708477\|RGD:9589113
Biological Process	GO:0048709	oligodendrocyte differentiation	Ptprz1	IMP		Mouse	MGI:MGI:5295220\|PMID:21969550
Biological Process	GO:0048709	oligodendrocyte differentiation	Ptprz1	IEP		Rat	PMID:8812065\|RGD:9590122
Biological Process	GO:0035335	peptidyl-tyrosine dephosphorylation	Ptprz1	IMP		Mouse	MGI:MGI:3622611\|PMID:16513268
Biological Process	GO:0035335	peptidyl-tyrosine dephosphorylation	Ptprz1	IDA		Rat	PMID:16814777\|RGD:11344935
Biological Process	GO:0035335	peptidyl-tyrosine dephosphorylation	Ptprz1	IDA		Rat	PMID:21890632\|RGD:9590130
Biological Process	GO:0030335	positive regulation of cell migration	Ptprz1	IDA		Rat	PMID:11340082\|RGD:1582484
Biological Process	GO:1900006	positive regulation of dendrite development	Ptprz1	IDA		Rat	PMID:8625816\|RGD:9589112
Biological Process	GO:0048146	positive regulation of fibroblast proliferation	Ptprz1	IDA		Rat	PMID:9705269\|RGD:9589122
Biological Process	GO:1901216	positive regulation of neuron death	Ptprz1	IDA		Rat	PMID:11343829\|RGD:9589126
Biological Process	GO:2001224	positive regulation of neuron migration	Ptprz1	IMP		Rat	PMID:9660874\|RGD:9589123
Biological Process	GO:0010976	positive regulation of neuron projection development	Ptprz1	IMP		Rat	PMID:8702927\|RGD:9589111
Biological Process	GO:0048714	positive regulation of oligodendrocyte differentiation	Ptprz1	IMP		Rat	PMID:30667096\|RGD:14397553
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	Ptprz1	IDA		Rat	PMID:8625816\|RGD:9589112
Biological Process	GO:1900149	positive regulation of Schwann cell migration	Ptprz1	IMP		Rat	PMID:11520897\|RGD:9590114
Biological Process	GO:0006470	protein dephosphorylation	Ptprz1	IDA		Rat	PMID:11381105\|RGD:9589125
Biological Process	GO:0006470	protein dephosphorylation	Ptprz1	IDA		Rat	PMID:17646177\|RGD:9590121
Biological Process	GO:0048814	regulation of dendrite morphogenesis	Ptprz1	IMP		Rat	PMID:12684467\|RGD:9589124
Biological Process	GO:0031641	regulation of myelination	Ptprz1	IMP		Mouse	MGI:MGI:5805301\|PMID:27445335
Biological Process	GO:0070445	regulation of oligodendrocyte progenitor proliferation	Ptprz1	IMP		Mouse	MGI:MGI:5295220\|PMID:21969550
Biological Process	GO:0008542	visual learning	Ptprz1	IEP		Rat	PMID:12737936\|RGD:9590120

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/17/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.