Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PTX3
  • Mouse genes Ptx3
  • Rat genes Ptx3
  • Zfish genes ptx3a,ptx3b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ptx3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001872	(1->3)-beta-D-glucan binding	Ptx3	IMP		Mouse	PMID:14726497
Molecular Function	GO:0001849	complement component C1q complex binding	PTX3	IDA		Human	PMID:23544079
Molecular Function	GO:0042802	identical protein binding	PTX3	IPI	UniProtKB:P26022	Human	PMID:20363749
Molecular Function	GO:0005515	protein binding	PTX3	IPI	UniProtKB:P08603	Human	PMID:19050261
Molecular Function	GO:0005515	protein binding	PTX3	IPI	UniProtKB:O00602	Human	PMID:19632990
Molecular Function	GO:0005515	protein binding	PTX3	IPI	UniProtKB:P08603	Human	PMID:19632990
Molecular Function	GO:0005515	protein binding	PTX3	IPI	UniProtKB:Q15485	Human	PMID:19632990
Molecular Function	GO:0005515	protein binding	PTX3	IPI	UniProtKB:P09038	Human	PMID:20363749
Molecular Function	GO:0005515	protein binding	PTX3	IPI	UniProtKB:O00602:PRO_0000009136	Human	PMID:21490156
Molecular Function	GO:0005515	protein binding	PTX3	IPI	UniProtKB:Q15485	Human	PMID:21490156
Molecular Function	GO:0005515	protein binding	PTX3	IPI	UniProtKB:P09038	Human	PMID:22267482
Molecular Function	GO:0005515	protein binding	PTX3	IPI	UniProtKB:P98066	Human	PMID:22267482
Molecular Function	GO:0005515	protein binding	PTX3	IPI	UniProtKB:P08603-2	Human	PMID:29374201
Molecular Function	GO:0005515	protein binding	PTX3	IPI	UniProtKB:P0DTC2|UniProtKB:P0DTC9	Human	PMID:35102342
Molecular Function	GO:0005515	protein binding	PTX3	IPI	UniProtKB:P0DTC9	Human	PMID:35102342
Molecular Function	GO:0005515	protein binding	Ptx3	IPI	PR:Q61702	Mouse	PMID:17675295
Molecular Function	GO:0046790	virion binding	PTX3	IDA		Human	PMID:23544079
Cellular Component	GO:0031012	extracellular matrix	Ptx3	IDA		Mouse	PMID:17675295
Cellular Component	GO:0005615	extracellular space	PTX3	IDA		Human	PMID:23544079
Cellular Component	GO:0005615	extracellular space	Ptx3	HDA		Mouse	MGI:MGI:5640941|PMID:24006456
Biological Process	GO:0030198	extracellular matrix organization	Ptx3	IMP		Mouse	PMID:17675295
Biological Process	GO:0030198	extracellular matrix organization	Ptx3	IDA		Mouse	PMID:17675295
Biological Process	GO:0045087	innate immune response	PTX3	IDA		Human	PMID:23544079
Biological Process	GO:0044869	negative regulation by host of viral exo-alpha-sialidase activity	PTX3	IDA		Human	PMID:23544079
Biological Process	GO:0044871	negative regulation by host of viral glycoprotein metabolic process	PTX3	IDA		Human	PMID:23544079
Biological Process	GO:1903016	negative regulation of exo-alpha-sialidase activity	PTX3	IDA		Human	PMID:23544079
Biological Process	GO:1903019	negative regulation of glycoprotein metabolic process	PTX3	IDA		Human	PMID:23544079
Biological Process	GO:0046597	negative regulation of viral entry into host cell	PTX3	IDA		Human	PMID:23544079
Biological Process	GO:0008228	opsonization	Ptx3	IMP		Mouse	PMID:14726497
Biological Process	GO:0001550	ovarian cumulus expansion	Ptx3	IMP		Mouse	PMID:17675295
Biological Process	GO:0001550	ovarian cumulus expansion	Ptx3	IDA		Mouse	PMID:17675295
Biological Process	GO:0045429	positive regulation of nitric oxide biosynthetic process	Ptx3	IMP		Mouse	PMID:14726497
Biological Process	GO:0050766	positive regulation of phagocytosis	Ptx3	IMP		Mouse	PMID:14726497
Biological Process	GO:0001878	response to yeast	Ptx3	IMP		Mouse	PMID:14726497

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern