Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PUM1
  • Mouse genes Pum1
  • Rat genes Pum1
  • Zfish genes pum1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pum1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0035198	miRNA binding	PUM1	IDA		Human	PMID:28431233
Molecular Function	GO:0003730	mRNA 3'-UTR binding	PUM1	IDA		Human	PMID:18776931
Molecular Function	GO:0003730	mRNA 3'-UTR binding	PUM1	IDA		Human	PMID:20818387
Molecular Function	GO:0003730	mRNA 3'-UTR binding	PUM1	IDA		Human	PMID:21572425
Molecular Function	GO:0003730	mRNA 3'-UTR binding	PUM1	IDA		Human	PMID:25768905
Molecular Function	GO:0003730	mRNA 3'-UTR binding	Pum1	IDA		Mouse	MGI:MGI:5640888|PMID:25768905
Molecular Function	GO:0003730	mRNA 3'-UTR binding	Pum1	IDA		Mouse	MGI:MGI:5315177|PMID:22342750
Molecular Function	GO:0003729	mRNA binding	pum1	IDA		Zfish	PMID:24062337
Molecular Function	GO:0003729	mRNA binding	pum1	IDA		Zfish	PMID:30103945
Molecular Function	GO:0005515	protein binding	PUM1	IPI	UniProtKB:Q2Q1W2	Human	PMID:23125361
Molecular Function	GO:0005515	protein binding	PUM1	IPI	UniProtKB:Q96C10	Human	PMID:25340845
Molecular Function	GO:0005515	protein binding	PUM1	IPI	UniProtKB:O15354	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PUM1	IPI	UniProtKB:O76024	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PUM1	IPI	UniProtKB:P28799	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PUM1	IPI	UniProtKB:P28799-2	Human	PMID:32814053
Molecular Function	GO:0003723	RNA binding	PUM1	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	PUM1	HDA		Human	PMID:22681889
Molecular Function	GO:0003723	RNA binding	PUM1	IDA		Human	PMID:26724866
Cellular Component	GO:0005737	cytoplasm	Pum1	IDA		Mouse	MGI:MGI:5315177|PMID:22342750
Cellular Component	GO:0010494	cytoplasmic stress granule	PUM1	IDA		Human	PMID:25340845
Cellular Component	GO:0005829	cytosol	PUM1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	PUM1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0000932	P-body	PUM1	IDA		Human	PMID:20818387
Biological Process	GO:0008344	adult locomotory behavior	Pum1	IMP		Mouse	MGI:MGI:5640888|PMID:25768905
Biological Process	GO:0035196	miRNA processing	PUM1	IMP		Human	PMID:28431233
Biological Process	GO:0061157	mRNA destabilization	Pum1	IDA		Mouse	MGI:MGI:5640888|PMID:25768905
Biological Process	GO:0019094	pole plasm mRNA localization	pum1	IGI	ZFIN:ZDB-GENE-000406-10	Zfish	PMID:24062337
Biological Process	GO:2000637	positive regulation of miRNA-mediated gene silencing	PUM1	IDA		Human	PMID:20818387
Biological Process	GO:2000637	positive regulation of miRNA-mediated gene silencing	PUM1	IDA		Human	PMID:22345517
Biological Process	GO:1900246	positive regulation of RIG-I signaling pathway	PUM1	IDA		Human	PMID:25340845
Biological Process	GO:0016441	post-transcriptional gene silencing	Pum1	IMP		Mouse	MGI:MGI:5640939|PMID:24412312
Biological Process	GO:0016441	post-transcriptional gene silencing	Pum1	IMP		Mouse	MGI:MGI:5315177|PMID:22342750
Biological Process	GO:0010608	post-transcriptional regulation of gene expression	PUM1	IDA		Human	PMID:25100735
Biological Process	GO:0010608	post-transcriptional regulation of gene expression	PUM1	IMP		Human	PMID:28431233
Biological Process	GO:0010608	post-transcriptional regulation of gene expression	Pum1	IMP		Mouse	PMID:25100735
Biological Process	GO:0051726	regulation of cell cycle	PUM1	IDA		Human	PMID:20818387
Biological Process	GO:0051983	regulation of chromosome segregation	PUM1	IDA		Human	PMID:26724866
Biological Process	GO:0043488	regulation of mRNA stability	PUM1	IDA		Human	PMID:26724866
Biological Process	GO:0007283	spermatogenesis	Pum1	IMP		Mouse	MGI:MGI:5315177|PMID:22342750
Biological Process	GO:0048863	stem cell differentiation	Pum1	IMP		Mouse	MGI:MGI:5640939|PMID:24412312

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern