Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PUM2
  • Mouse genes Pum2
  • Rat genes Pum2
  • Zfish genes pum2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pum2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0106222	lncRNA binding	Pum2	IDA		Mouse	PMID:30735131
Molecular Function	GO:0035198	miRNA binding	PUM2	IDA		Human	PMID:28431233
Molecular Function	GO:0003730	mRNA 3'-UTR binding	PUM2	IDA		Human	PMID:18776931
Molecular Function	GO:0005515	protein binding	PUM2	IPI	UniProtKB:Q9NQZ3	Human	PMID:12511597
Molecular Function	GO:0005515	protein binding	PUM2	IPI	UniProtKB:Q8N9W6	Human	PMID:15806553
Molecular Function	GO:0005515	protein binding	PUM2	IPI	UniProtKB:O95295	Human	PMID:19168546
Molecular Function	GO:0005515	protein binding	PUM2	IPI	UniProtKB:Q8WY41	Human	PMID:19168546
Molecular Function	GO:0005515	protein binding	PUM2	IPI	UniProtKB:Q8WY41	Human	PMID:21800163
Molecular Function	GO:0005515	protein binding	PUM2	IPI	UniProtKB:Q9Q2G4	Human	PMID:22190034
Molecular Function	GO:0005515	protein binding	PUM2	IPI	UniProtKB:Q2Q1W2	Human	PMID:23125361
Molecular Function	GO:0005515	protein binding	PUM2	IPI	UniProtKB:Q96C10	Human	PMID:25340845
Molecular Function	GO:0005515	protein binding	Pum2	IPI	UniProtKB:P60324	Mouse	MGI:MGI:3772433|PMID:18089289
Molecular Function	GO:0005515	protein binding	Pum2	IPI	UniProtKB:Q7TN99	Mouse	MGI:MGI:5520034|PMID:22496444
Molecular Function	GO:0062104	pumilio-response element binding	Pum2	IDA		Mouse	PMID:30735131
Molecular Function	GO:0003723	RNA binding	PUM2	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	PUM2	HDA		Human	PMID:22681889
Molecular Function	GO:0003723	RNA binding	PUM2	IDA		Human	PMID:26724866
Molecular Function	GO:0003723	RNA binding	Pum2	IDA		Mouse	PMID:11780640
Cellular Component	GO:0010494	cytoplasmic stress granule	PUM2	IDA		Human	PMID:25340845
Cellular Component	GO:0010494	cytoplasmic stress granule	Pum2	IDA		Mouse	MGI:MGI:4820495|PMID:19861488
Cellular Component	GO:0010494	cytoplasmic stress granule	Pum2	IDA		Mouse	PMID:16775137
Cellular Component	GO:0005829	cytosol	PUM2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0031965	nuclear membrane	PUM2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0048471	perinuclear region of cytoplasm	PUM2	IDA		Human	PMID:19168546
Biological Process	GO:0060612	adipose tissue development	Pum2	IDA		Mouse	PMID:30735131
Biological Process	GO:0051276	chromosome organization	Pum2	IDA		Mouse	PMID:30735131
Biological Process	GO:0001942	hair follicle development	Pum2	IDA		Mouse	PMID:30735131
Biological Process	GO:0035196	miRNA processing	PUM2	IMP		Human	PMID:28431233
Biological Process	GO:0007005	mitochondrion organization	Pum2	IDA		Mouse	PMID:30735131
Biological Process	GO:2000637	positive regulation of miRNA-mediated gene silencing	PUM2	IMP		Human	PMID:22345517
Biological Process	GO:1900246	positive regulation of RIG-I signaling pathway	PUM2	IDA		Human	PMID:25340845
Biological Process	GO:0010608	post-transcriptional regulation of gene expression	PUM2	IDA		Human	PMID:25100735
Biological Process	GO:0010608	post-transcriptional regulation of gene expression	PUM2	IMP		Human	PMID:28431233
Biological Process	GO:0010608	post-transcriptional regulation of gene expression	Pum2	IMP		Mouse	PMID:25100735
Biological Process	GO:0051983	regulation of chromosome segregation	PUM2	IDA		Human	PMID:26724866
Biological Process	GO:2000739	regulation of mesenchymal stem cell differentiation	pum2	IMP	ZFIN:ZDB-GENO-211014-2	Zfish	PMID:31595981
Biological Process	GO:0043488	regulation of mRNA stability	PUM2	IDA		Human	PMID:26724866
Biological Process	GO:0022904	respiratory electron transport chain	Pum2	IDA		Mouse	PMID:30735131
Biological Process	GO:0001501	skeletal system development	Pum2	IDA		Mouse	PMID:30735131
Biological Process	GO:0034063	stress granule assembly	Pum2	IDA		Mouse	PMID:16775137

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern