Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PURA
  • Mouse genes Pura
  • Rat genes Pura
  • Zfish genes puraa,purab
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pura

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	Pura	IDA		Mouse	PMID:10049721
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Pura	IDA		Mouse	PMID:15282343
Molecular Function	GO:0140297	DNA-binding transcription factor binding	Pura	IPI	UniProtKB:Q61501	Mouse	MGI:MGI:3687670|PMID:10597240
Molecular Function	GO:0140297	DNA-binding transcription factor binding	Pura	IPI	UniProtKB:O35295	Mouse	MGI:MGI:1336864|PMID:10318844
Molecular Function	GO:0003690	double-stranded DNA binding	Pura	IDA		Mouse	PMID:15282343
Molecular Function	GO:0003690	double-stranded DNA binding	puraa	IDA		Zfish	PMID:15464585
Molecular Function	GO:0003691	double-stranded telomeric DNA binding	PURA	IDA		Human	PMID:15777841
Molecular Function	GO:0000900	mRNA regulatory element binding translation repressor activity	Pura	IDA		Mouse	MGI:MGI:3688338|PMID:12933792
Molecular Function	GO:0005515	protein binding	PURA	IPI	UniProtKB:P03070	Human	PMID:7592647
Molecular Function	GO:0005515	protein binding	PURA	IPI	UniProtKB:P06400	Human	PMID:7592647
Molecular Function	GO:0005515	protein binding	PURA	IPI	UniProtKB:P03070	Human	PMID:9830007
Molecular Function	GO:0005515	protein binding	PURA	IPI	UniProtKB:P03072	Human	PMID:9830007
Molecular Function	GO:0005515	protein binding	Pura	IPI	PR:Q8BUN5	Mouse	PMID:15282343
Molecular Function	GO:0005515	protein binding	Pura	IPI	PR:P11416-1	Mouse	PMID:18495661
Molecular Function	GO:0005515	protein binding	Pura	IPI	PR:P49615	Mouse	PMID:12972605
Molecular Function	GO:0005515	protein binding	Pura	IPI	PR:Q62432	Mouse	PMID:15282343
Molecular Function	GO:0005515	protein binding	Pura	IPI	PR:O89090	Mouse	PMID:15282343
Molecular Function	GO:0005515	protein binding	Pura	IPI	PR:P97471	Mouse	PMID:15282343
Molecular Function	GO:0032422	purine-rich negative regulatory element binding	Pura	IDA		Mouse	MGI:MGI:3688338|PMID:12933792
Molecular Function	GO:0003723	RNA binding	PURA	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	PURA	HDA		Human	PMID:22681889
Molecular Function	GO:0003697	single-stranded DNA binding	Pura	IDA		Mouse	MGI:MGI:3688338|PMID:12933792
Molecular Function	GO:0003697	single-stranded DNA binding	Pura	IDA		Mouse	MGI:MGI:1336864|PMID:10318844
Molecular Function	GO:0046332	SMAD binding	Pura	IDA		Mouse	PMID:15282343
Molecular Function	GO:0140416	transcription regulator inhibitor activity	Pura	IDA		Mouse	MGI:MGI:3687670|PMID:10597240
Cellular Component	GO:0005737	cytoplasm	Pura	IDA		Mouse	PMID:12972605
Cellular Component	GO:0030425	dendrite	Pura	IPI		Mouse	MGI:MGI:3530979|PMID:15312650
Cellular Component	GO:0030425	dendrite	Pura	IDA		Mouse	PMID:18495661
Cellular Component	GO:0032839	dendrite cytoplasm	Pura	IPI		Mouse	MGI:MGI:3530979|PMID:15312650
Cellular Component	GO:0098978	glutamatergic synapse	Pura	IDA		Mouse	PMID:28404748
Cellular Component	GO:0043025	neuronal cell body	Pura	IDA		Mouse	PMID:18495661
Cellular Component	GO:0005634	nucleus	PURA	IDA		Human	PMID:9716182
Cellular Component	GO:0005634	nucleus	Pura	IDA		Mouse	PMID:12972605
Cellular Component	GO:0005634	nucleus	Pura	IDA		Mouse	PMID:15282343
Cellular Component	GO:0098794	postsynapse	Pura	IDA		Mouse	PMID:28404748
Cellular Component	GO:0014069	postsynaptic density	Pura	EXP		Rat	PMID:14532281|RGD:13702402
Cellular Component	GO:0014069	postsynaptic density	Pura	IDA		Rat	PMID:14532281|RGD:13702402
Biological Process	GO:0008283	cell population proliferation	Pura	IMP	MGI:MGI:2677937	Mouse	PMID:12972605
Biological Process	GO:0098963	dendritic transport of messenger ribonucleoprotein complex	Pura	IPI		Mouse	PMID:15312650
Biological Process	GO:0098963	dendritic transport of messenger ribonucleoprotein complex	Pura	IDA		Mouse	PMID:15312650
Biological Process	GO:0098963	dendritic transport of messenger ribonucleoprotein complex	Pura	IMP		Mouse	PMID:15312650
Biological Process	GO:0006268	DNA unwinding involved in DNA replication	PURA	IDA		Human	PMID:15777841
Biological Process	GO:0050673	epithelial cell proliferation	Pura	IMP	MGI:MGI:2677937	Mouse	PMID:12972605
Biological Process	GO:0046651	lymphocyte proliferation	Pura	IMP	MGI:MGI:2677937	Mouse	PMID:12972605
Biological Process	GO:0043433	negative regulation of DNA-binding transcription factor activity	Pura	IDA		Mouse	MGI:MGI:3687670|PMID:10597240
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Pura	IDA		Mouse	MGI:MGI:3688338|PMID:12933792
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Pura	IDA		Mouse	PMID:15282343
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	PURA	IDA		Human	PMID:26089202
Biological Process	GO:0007399	nervous system development	Pura	IMP	MGI:MGI:2677937	Mouse	PMID:12972605
Biological Process	GO:0008284	positive regulation of cell population proliferation	Pura	IMP	MGI:MGI:2677937	Mouse	PMID:12972605

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern