Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PUS1
  • Mouse genes Pus1
  • Rat genes Pus1
  • Zfish genes pus1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pus1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Pus1	IDA		Mouse	PMID:15327771
Molecular Function	GO:0030374	nuclear receptor coactivator activity	Pus1	IDA		Mouse	PMID:15327771
Molecular Function	GO:0005515	protein binding	Pus1	IPI	PR:P18911	Mouse	PMID:15327771
Molecular Function	GO:0009982	pseudouridine synthase activity	PUS1	EXP		Human	PMID:15772074
Molecular Function	GO:0009982	pseudouridine synthase activity	PUS1	IMP		Human	PMID:15772074
Molecular Function	GO:0009982	pseudouridine synthase activity	PUS1	EXP		Human	PMID:22102571
Molecular Function	GO:0009982	pseudouridine synthase activity	PUS1	IMP		Human	PMID:24722331
Molecular Function	GO:0009982	pseudouridine synthase activity	PUS1	IDA		Human	PMID:31477916
Molecular Function	GO:0009982	pseudouridine synthase activity	PUS1	IDA		Human	PMID:35051350
Molecular Function	GO:0009982	pseudouridine synthase activity	Pus1	IMP		Mouse	MGI:MGI:5810940|PMID:27197761
Molecular Function	GO:0009982	pseudouridine synthase activity	Pus1	IMP		Mouse	PMID:15327771
Molecular Function	GO:0009982	pseudouridine synthase activity	Pus1	IDA		Mouse	PMID:11027153
Molecular Function	GO:0003723	RNA binding	PUS1	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	PUS1	HDA		Human	PMID:22681889
Molecular Function	GO:0002153	steroid receptor RNA activator RNA binding	PUS1	IDA		Human	PMID:24722331
Molecular Function	GO:0000049	tRNA binding	PUS1	IDA		Human	PMID:23707380
Molecular Function	GO:0106029	tRNA pseudouridine synthase activity	Pus1	IDA		Mouse	MGI:MGI:1928672|PMID:10094309
Cellular Component	GO:0005737	cytoplasm	PUS1	IDA		Human	PMID:15772074
Cellular Component	GO:0005739	mitochondrion	PUS1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	PUS1	IDA		Human	PMID:15772074
Cellular Component	GO:0005739	mitochondrion	PUS1	IDA		Human	PMID:28082677
Cellular Component	GO:0005730	nucleolus	Pus1	IDA		Mouse	PMID:15327771
Cellular Component	GO:0005654	nucleoplasm	PUS1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	PUS1	IDA		Human	PMID:15772074
Cellular Component	GO:0005634	nucleus	Pus1	IDA		Mouse	PMID:15327771
Cellular Component	GO:0005667	transcription regulator complex	Pus1	IDA		Mouse	PMID:15327771
Biological Process	GO:1990481	mRNA pseudouridine synthesis	PUS1	IDA		Human	PMID:31477916
Biological Process	GO:1990481	mRNA pseudouridine synthesis	PUS1	IDA		Human	PMID:35051350
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Pus1	IDA		Mouse	PMID:15327771
Biological Process	GO:0031119	tRNA pseudouridine synthesis	PUS1	IMP		Human	PMID:15772074
Biological Process	GO:0031119	tRNA pseudouridine synthesis	Pus1	IMP		Mouse	MGI:MGI:5810940|PMID:27197761
Biological Process	GO:0031119	tRNA pseudouridine synthesis	Pus1	IDA		Mouse	MGI:MGI:1928672|PMID:10094309
Biological Process	GO:0031119	tRNA pseudouridine synthesis	Pus1	IDA		Mouse	PMID:11027153
Biological Process	GO:0031119	tRNA pseudouridine synthesis	Pus1	IDA		Mouse	PMID:11085940
Biological Process	GO:0031119	tRNA pseudouridine synthesis	Pus1	IDA		Mouse	PMID:15327771

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern