Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PVR
  • Mouse genes Pvr
  • Rat genes Pvr
  • Zfish genes pvrl2l
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pvr

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0050839	cell adhesion molecule binding	PVR	IPI	UniProtKB:Q15762	Human	PMID:12913096
Molecular Function	GO:0045503	dynein light chain binding	Pvr	IPI	PR:P51807	Mouse	PMID:11751937
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:Q495A1	Human	PMID:19011627
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:Q15762	Human	PMID:21982860
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:Q495A1	Human	PMID:21982860
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:P60409	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:P60410	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:P60411	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:Q7Z3S9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:Q9BRI3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:Q495A1	Human	PMID:28515320
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:Q15762	Human	PMID:30591568
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:Q8K4F0	Human	PMID:30591568
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:Q7Z3S9	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:Q9BRI3	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:A8MQ03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:B2RUZ4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:O00767	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:O43934	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:O95159	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:O95183	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:P0DJD7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:P0DPK4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:P11686	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:P30536	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:P49639	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:P55061	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:P56851	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:P59542	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:P60410	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:Q04941	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:Q07627	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:Q08722-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:Q15125	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:Q15848	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:Q4LDR2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:Q5BVD1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:Q5SQN1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:Q6PI78	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:Q6PL45-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:Q6UX06	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:Q86W74-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:Q8IUG1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:Q8IY26	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:Q8N2H4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:Q8N6F1-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:Q8N966	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:Q8NBD8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:Q8NBI2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:Q92982	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:Q969K7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:Q969S0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:Q96GQ5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:Q96JW4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:Q96MV8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:Q96PS8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:Q9BRI3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:Q9BSE2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:Q9BVK8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:Q9BYQ3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:Q9BYR6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:Q9BYR8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:Q9BZW4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:Q9HCP6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:Q9NZD1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:Q9NZG7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PVR	IPI	UniProtKB:Q9Y5U4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Pvr	IPI	PR:Q8K4F0	Mouse	PMID:15752754
Molecular Function	GO:0005515	protein binding	Pvr	IPI	PR:Q8K4F0	Mouse	PMID:21416464
Molecular Function	GO:0005515	protein binding	Pvr	IPI	PR:P86176	Mouse	PMID:24658051
Molecular Function	GO:0005515	protein binding	Pvr	IPI	UniProtKB:Q9D006	Mouse	PMID:12740392
Molecular Function	GO:0005515	protein binding	Pvr	IPI	PR:P86176	Mouse	PMID:21416464
Molecular Function	GO:0005515	protein binding	Pvr	IPI	PR:Q8K4F0	Mouse	PMID:24658051
Molecular Function	GO:0005515	protein binding	Pvr	IPI	UniProtKB:Q9D006	Mouse	PMID:12759359
Molecular Function	GO:0005515	protein binding	Pvr	IPI	PR:Q3U0X8	Mouse	PMID:24658051
Molecular Function	GO:0005515	protein binding	pvrl2l	IPI	UniProtKB:A1L2D6	Zfish	PMID:20802085|ZFIN:ZDB-PUB-100910-6
Molecular Function	GO:0001618	virus receptor activity	Pvr	IMP		Rat	PMID:11255021|RGD:68704
Cellular Component	GO:0009986	cell surface	PVR	IDA		Human	PMID:16831868
Cellular Component	GO:0009986	cell surface	Pvr	IDA		Mouse	PMID:27733379
Cellular Component	GO:0005925	focal adhesion	PVR	HDA		Human	PMID:21423176
Cellular Component	GO:0016020	membrane	PVR	IDA		Human	PMID:12913096
Cellular Component	GO:0005886	plasma membrane	Pvr	IDA		Mouse	PMID:22027834
Biological Process	GO:0016477	cell migration	Pvr	IDA		Mouse	PMID:12740392
Biological Process	GO:0098609	cell-cell adhesion	Pvr	IDA		Mouse	PMID:12740392
Biological Process	GO:0045954	positive regulation of natural killer cell mediated cytotoxicity	PVR	IMP		Human	PMID:16304049
Biological Process	GO:0002860	positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target	PVR	IMP		Human	PMID:12913096
Biological Process	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity	PVR	IMP		Human	PMID:12913096
Biological Process	GO:0060370	susceptibility to T cell mediated cytotoxicity	PVR	IDA		Human	PMID:15039383

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern