Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PWWP2B
  • Mouse genes Pwwp2b
  • Rat genes Pwwp2b
  • Zfish genes pwwp2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pwwp2b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0120325	NuRD complex binding	PWWP2B	IDA		Human	PMID:30228260
Molecular Function	GO:0005515	protein binding	PWWP2B	IPI	UniProtKB:P25788	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PWWP2B	IPI	UniProtKB:O09106	Human	PMID:30228260
Molecular Function	GO:0005515	protein binding	PWWP2B	IPI	UniProtKB:Q8K4B0	Human	PMID:30228260
Molecular Function	GO:0005515	protein binding	PWWP2B	IPI	UniProtKB:A6NEM1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PWWP2B	IPI	UniProtKB:Q9NYB9-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Pwwp2b	IPI	UniProtKB:O09106|UniProtKB:P46737|UniProtKB:P70288|UniProtKB:Q60972|UniProtKB:Q60973|UniProtKB:Q7TSH3|UniProtKB:Q8K4B0|UniProtKB:Q924K8|UniProtKB:Q9R190	Mouse	MGI:MGI:6867105|PMID:34180153
Cellular Component	GO:0005654	nucleoplasm	PWWP2B	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Pwwp2b	IDA		Mouse	MGI:MGI:6867105|PMID:34180153
Biological Process	GO:0006338	chromatin remodeling	Pwwp2b	IMP		Mouse	MGI:MGI:6709552|PMID:30228260
Biological Process	GO:0035067	negative regulation of histone acetylation	Pwwp2b	IMP		Mouse	MGI:MGI:6867105|PMID:34180153
Biological Process	GO:0032968	positive regulation of transcription elongation by RNA polymerase II	Pwwp2b	IMP		Mouse	MGI:MGI:6709552|PMID:30228260
Biological Process	GO:0120161	regulation of cold-induced thermogenesis	Pwwp2b	IMP		Mouse	MGI:MGI:6867105|PMID:34180153

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern