Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PXDN
  • Mouse genes Pxdn
  • Rat genes Pxdn
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pxdn

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005201	extracellular matrix structural constituent	PXDN	IDA		Human	PMID:19590037
Molecular Function	GO:0020037	heme binding	PXDN	IDA		Human	PMID:18929642
Molecular Function	GO:0043237	laminin-1 binding	PXDN	IDA		Human	PMID:32485152
Molecular Function	GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	PXDN	IDA		Human	PMID:22842973
Molecular Function	GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	PXDN	IDA		Human	PMID:27697841
Molecular Function	GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	PXDN	IMP		Human	PMID:32571911
Molecular Function	GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	Pxdn	IDA		Mouse	MGI:MGI:6870970|PMID:22842973
Molecular Function	GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	Pxdn	IMP		Mouse	MGI:MGI:6444560|PMID:32571911
Molecular Function	GO:0004601	peroxidase activity	PXDN	IDA		Human	PMID:18929642
Molecular Function	GO:0004601	peroxidase activity	PXDN	IDA		Human	PMID:19590037
Cellular Component	GO:0005604	basement membrane	Pxdn	IDA		Mouse	MGI:MGI:6870970|PMID:22842973
Cellular Component	GO:0009986	cell surface	PXDN	IDA		Human	PMID:25708780
Cellular Component	GO:0062023	collagen-containing extracellular matrix	PXDN	IDA		Human	PMID:19590037
Cellular Component	GO:0062023	collagen-containing extracellular matrix	PXDN	HDA		Human	PMID:23979707
Cellular Component	GO:0062023	collagen-containing extracellular matrix	PXDN	HDA		Human	PMID:28327460
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Pxdn	IDA		Mouse	MGI:MGI:3851833|PMID:19590037
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Pxdn	HDA		Mouse	MGI:MGI:6201834|PMID:22159717
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Pxdn	HDA		Mouse	MGI:MGI:6201853|PMID:28071719
Cellular Component	GO:0005783	endoplasmic reticulum	PXDN	IDA		Human	PMID:19590037
Cellular Component	GO:0005783	endoplasmic reticulum	PXDN	IDA		Human	PMID:25708780
Cellular Component	GO:0070062	extracellular exosome	PXDN	HDA		Human	PMID:23533145
Cellular Component	GO:0031012	extracellular matrix	PXDN	IDA		Human	PMID:26178375
Cellular Component	GO:0005615	extracellular space	PXDN	IDA		Human	PMID:18929642
Cellular Component	GO:0005615	extracellular space	Pxdn	HDA		Mouse	MGI:MGI:5640941|PMID:24006456
Biological Process	GO:0001525	angiogenesis	PXDN	IMP		Human	PMID:29982533
Biological Process	GO:0070831	basement membrane assembly	PXDN	IMP		Human	PMID:32543734
Biological Process	GO:0070831	basement membrane assembly	PXDN	IMP		Human	PMID:25708780
Biological Process	GO:0070831	basement membrane assembly	PXDN	IMP		Human	PMID:27697841
Biological Process	GO:0070831	basement membrane assembly	PXDN	IMP		Human	PMID:32571911
Biological Process	GO:0070831	basement membrane assembly	Pxdn	IMP		Mouse	MGI:MGI:6444560|PMID:32571911
Biological Process	GO:0070831	basement membrane assembly	Pxdn	IDA		Mouse	MGI:MGI:6870970|PMID:22842973
Biological Process	GO:0070831	basement membrane assembly	Pxdn	IMP		Mouse	MGI:MGI:6109597|PMID:25708780
Biological Process	GO:0071711	basement membrane organization	Pxdn	IMP		Mouse	MGI:MGI:6114330|PMID:28424209
Biological Process	GO:0071711	basement membrane organization	Pxdn	IMP		Mouse	MGI:MGI:5584206|PMID:24895407
Biological Process	GO:0007155	cell adhesion	Pxdn	IMP		Mouse	MGI:MGI:5584206|PMID:24895407
Biological Process	GO:0030199	collagen fibril organization	PXDN	IMP		Human	PMID:22842973
Biological Process	GO:0030198	extracellular matrix organization	PXDN	IDA		Human	PMID:19590037
Biological Process	GO:0030198	extracellular matrix organization	Pxdn	IDA		Mouse	MGI:MGI:3851833|PMID:19590037
Biological Process	GO:0001654	eye development	Pxdn	IMP		Mouse	MGI:MGI:6400066|PMID:31817535
Biological Process	GO:0042744	hydrogen peroxide catabolic process	PXDN	IDA		Human	PMID:18929642
Biological Process	GO:0051260	protein homooligomerization	PXDN	IDA		Human	PMID:25708780
Biological Process	GO:0051260	protein homooligomerization	PXDN	IDA		Human	PMID:25713063
Biological Process	GO:0070207	protein homotrimerization	PXDN	IDA		Human	PMID:25713063
Biological Process	GO:0070207	protein homotrimerization	PXDN	IDA		Human	PMID:31295557
Biological Process	GO:0070207	protein homotrimerization	PXDN	IMP		Human	PMID:32543734

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern