Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PXK
  • Mouse genes Pxk
  • Rat genes Pxk
  • Zfish genes pxk
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pxk

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	Pxk	IPI	UniProtKB:P14094|UniProtKB:P14094|UniProtKB:P97370|UniProtKB:P97370	Mouse	MGI:MGI:3588605|PMID:16135750
Cellular Component	GO:0034451	centriolar satellite	PXK	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005737	cytoplasm	Pxk	IDA		Mouse	MGI:MGI:3588605|PMID:16135750
Cellular Component	GO:0005829	cytosol	PXK	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	PXK	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	Pxk	IDA		Mouse	MGI:MGI:3588605|PMID:16135750
Cellular Component	GO:0032991	protein-containing complex	Pxk	IDA		Mouse	PMID:17606467
Biological Process	GO:0006954	inflammatory response	PXK	IMP		Human	PMID:18204446
Biological Process	GO:0050804	modulation of chemical synaptic transmission	Pxk	IEP		Mouse	MGI:MGI:3588605|PMID:16135750
Biological Process	GO:0032780	negative regulation of ATP-dependent activity	Pxk	IDA		Mouse	MGI:MGI:3588605|PMID:16135750
Biological Process	GO:0043271	negative regulation of monoatomic ion transport	Pxk	IDA		Mouse	MGI:MGI:3588605|PMID:16135750

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern