Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PYCARD
  • Mouse genes Pycard
  • Rat genes Pycard
  • Zfish genes pycard
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pycard

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0070700	BMP receptor binding	PYCARD	IPI	UniProtKB:Q13873	Human	PMID:24407287
Molecular Function	GO:0019899	enzyme binding	PYCARD	IPI	UniProtKB:P49916	Human	PMID:24407287
Molecular Function	GO:0042802	identical protein binding	PYCARD	IPI	UniProtKB:Q9ULZ3	Human	PMID:24630722
Molecular Function	GO:0042802	identical protein binding	PYCARD	IPI	UniProtKB:Q9ULZ3	Human	PMID:25006247
Molecular Function	GO:0042802	identical protein binding	PYCARD	IPI	UniProtKB:Q9ULZ3	Human	PMID:25416956
Molecular Function	GO:0042802	identical protein binding	PYCARD	IDA		Human	PMID:34341353
Molecular Function	GO:0042802	identical protein binding	Pycard	IPI	PR:Q9EPB4	Mouse	PMID:24407287
Molecular Function	GO:0005138	interleukin-6 receptor binding	PYCARD	IPI	UniProtKB:P40189	Human	PMID:24407287
Molecular Function	GO:0017024	myosin I binding	PYCARD	IPI	UniProtKB:O00159	Human	PMID:24407287
Molecular Function	GO:0002020	protease binding	PYCARD	IPI	UniProtKB:P98073	Human	PMID:24407287
Molecular Function	GO:0002020	protease binding	Pycard	IPI	RGD:2274	Rat	PMID:18367607|RGD:2315889
Molecular Function	GO:0002020	protease binding	Pycard	IPI	RGD:2274	Rat	PMID:19416975|RGD:5491011
Molecular Function	GO:0002020	protease binding	Pycard	IPI	RGD:621757	Rat	PMID:19416975|RGD:5491011
Molecular Function	GO:0005515	protein binding	PYCARD	IPI	UniProtKB:O15553	Human	PMID:11498534
Molecular Function	GO:0005515	protein binding	PYCARD	IPI	UniProtKB:Q96P20	Human	PMID:11786556
Molecular Function	GO:0005515	protein binding	PYCARD	IPI	UniProtKB:P59046	Human	PMID:12019269
Molecular Function	GO:0005515	protein binding	PYCARD	IPI	UniProtKB:Q8WXC3	Human	PMID:12656673
Molecular Function	GO:0005515	protein binding	PYCARD	IPI	UniProtKB:Q07812	Human	PMID:14730312
Molecular Function	GO:0005515	protein binding	PYCARD	IPI	UniProtKB:Q96P20	Human	PMID:15020601
Molecular Function	GO:0005515	protein binding	PYCARD	IPI	UniProtKB:Q9NX02	Human	PMID:15030775
Molecular Function	GO:0005515	protein binding	PYCARD	IPI	UniProtKB:Q56P42	Human	PMID:17178784
Molecular Function	GO:0005515	protein binding	PYCARD	IPI	UniProtKB:Q9C000	Human	PMID:17418785
Molecular Function	GO:0005515	protein binding	PYCARD	IPI	UniProtKB:O15553	Human	PMID:17964261
Molecular Function	GO:0005515	protein binding	PYCARD	IPI	UniProtKB:O14862	Human	PMID:19158675
Molecular Function	GO:0005515	protein binding	PYCARD	IPI	UniProtKB:Q96P20	Human	PMID:19158675
Molecular Function	GO:0005515	protein binding	PYCARD	IPI	UniProtKB:O14862	Human	PMID:19158676
Molecular Function	GO:0005515	protein binding	PYCARD	IPI	UniProtKB:O14862	Human	PMID:22286270
Molecular Function	GO:0005515	protein binding	PYCARD	IPI	UniProtKB:O14862	Human	PMID:24237704
Molecular Function	GO:0005515	protein binding	PYCARD	IPI	UniProtKB:O15327	Human	PMID:24407287
Molecular Function	GO:0005515	protein binding	PYCARD	IPI	UniProtKB:O43586	Human	PMID:24407287
Molecular Function	GO:0005515	protein binding	PYCARD	IPI	UniProtKB:P29590	Human	PMID:24407287
Molecular Function	GO:0005515	protein binding	PYCARD	IPI	UniProtKB:P33991	Human	PMID:24407287
Molecular Function	GO:0005515	protein binding	PYCARD	IPI	UniProtKB:P57740	Human	PMID:24407287
Molecular Function	GO:0005515	protein binding	PYCARD	IPI	UniProtKB:Q8IY82	Human	PMID:24407287
Molecular Function	GO:0005515	protein binding	PYCARD	IPI	UniProtKB:Q8N475	Human	PMID:24407287
Molecular Function	GO:0005515	protein binding	PYCARD	IPI	UniProtKB:Q8NB25	Human	PMID:24407287
Molecular Function	GO:0005515	protein binding	PYCARD	IPI	UniProtKB:Q8NEN0	Human	PMID:24407287
Molecular Function	GO:0005515	protein binding	PYCARD	IPI	UniProtKB:Q9BXJ9	Human	PMID:24407287
Molecular Function	GO:0005515	protein binding	PYCARD	IPI	UniProtKB:Q9NRE2	Human	PMID:24407287
Molecular Function	GO:0005515	protein binding	PYCARD	IPI	UniProtKB:Q9NX36	Human	PMID:24407287
Molecular Function	GO:0005515	protein binding	PYCARD	IPI	UniProtKB:Q9UPN4	Human	PMID:24407287
Molecular Function	GO:0005515	protein binding	PYCARD	IPI	UniProtKB:Q9WJR3	Human	PMID:24407287
Molecular Function	GO:0005515	protein binding	PYCARD	IPI	UniProtKB:Q9Y2U8	Human	PMID:24407287
Molecular Function	GO:0005515	protein binding	PYCARD	IPI	UniProtKB:O14862	Human	PMID:24531343
Molecular Function	GO:0005515	protein binding	PYCARD	IPI	UniProtKB:O14862	Human	PMID:24630722
Molecular Function	GO:0005515	protein binding	PYCARD	IPI	UniProtKB:P29466	Human	PMID:24630722
Molecular Function	GO:0005515	protein binding	PYCARD	IPI	UniProtKB:Q96P20	Human	PMID:24630722
Molecular Function	GO:0005515	protein binding	PYCARD	IPI	UniProtKB:O15553	Human	PMID:25006247
Molecular Function	GO:0005515	protein binding	PYCARD	IPI	UniProtKB:Q7RTR2	Human	PMID:25277106
Molecular Function	GO:0005515	protein binding	PYCARD	IPI	UniProtKB:Q13546	Human	PMID:25402006
Molecular Function	GO:0005515	protein binding	PYCARD	IPI	UniProtKB:O00471	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PYCARD	IPI	UniProtKB:P29466	Human	PMID:25605870
Molecular Function	GO:0005515	protein binding	PYCARD	IPI	UniProtKB:P43405	Human	PMID:25605870
Molecular Function	GO:0005515	protein binding	PYCARD	IPI	UniProtKB:Q96P20	Human	PMID:28229991
Molecular Function	GO:0005515	protein binding	PYCARD	IPI	UniProtKB:Q7RTR0	Human	PMID:28636595
Molecular Function	GO:0005515	protein binding	PYCARD	IPI	UniProtKB:P29466	Human	PMID:31421660
Molecular Function	GO:0005515	protein binding	PYCARD	IPI	UniProtKB:Q96P20	Human	PMID:31421660
Molecular Function	GO:0005515	protein binding	PYCARD	IPI	UniProtKB:Q96P20	Human	PMID:34341353
Molecular Function	GO:0005515	protein binding	Pycard	IPI	UniProtKB:Q8R4B8	Mouse	MGI:MGI:5466621|PMID:23143333
Molecular Function	GO:0005515	protein binding	Pycard	IPI	UniProtKB:P29452|UniProtKB:Q8R4B8	Mouse	MGI:MGI:5432942|PMID:22801494
Molecular Function	GO:0005515	protein binding	Pycard	IPI	UniProtKB:P29452|UniProtKB:Q8R4B8	Mouse	MGI:MGI:5915552|PMID:25605870
Molecular Function	GO:0005515	protein binding	Pycard	IPI	PR:P29452	Mouse	PMID:15190255
Molecular Function	GO:0005515	protein binding	Pycard	IPI	PR:Q91VJ1	Mouse	PMID:19158679
Molecular Function	GO:0005515	protein binding	Pycard	IPI	RGD:1310963	Rat	PMID:19416975|RGD:5491011
Molecular Function	GO:0005515	protein binding	Pycard	IPI	RGD:620692	Rat	PMID:19416975|RGD:5491011
Molecular Function	GO:0005515	protein binding	Pycard	IPI	RGD:735204	Rat	PMID:19416975|RGD:5491011
Molecular Function	GO:0005515	protein binding	pycard	IPI	ZFIN:ZDB-GENE-000616-3	Zfish	PMID:29791979
Molecular Function	GO:0005515	protein binding	pycard	IPI	ZFIN:ZDB-GENE-000511-2	Zfish	PMID:29791979
Molecular Function	GO:0046983	protein dimerization activity	PYCARD	IDA		Human	PMID:24531343
Molecular Function	GO:0046983	protein dimerization activity	Pycard	IMP		Mouse	MGI:MGI:5621259|PMID:24407287
Molecular Function	GO:0042803	protein homodimerization activity	PYCARD	IDA		Human	PMID:15030775
Molecular Function	GO:0032090	Pyrin domain binding	PYCARD	IPI	UniProtKB:Q96P20	Human	PMID:15030775
Molecular Function	GO:0032090	Pyrin domain binding	PYCARD	IPI	UniProtKB:Q9ULZ3	Human	PMID:15030775
Molecular Function	GO:0032090	Pyrin domain binding	pycard	IPI	ZFIN:ZDB-GENE-000616-3	Zfish	PMID:12464617
Molecular Function	GO:0044325	transmembrane transporter binding	Pycard	IPI	RGD:3241	Rat	PMID:19416975|RGD:5491011
Molecular Function	GO:0005523	tropomyosin binding	PYCARD	IPI	UniProtKB:P67936	Human	PMID:24407287
Cellular Component	GO:0097169	AIM2 inflammasome complex	PYCARD	IPI		Human	PMID:24630722
Cellular Component	GO:0097169	AIM2 inflammasome complex	PYCARD	IDA		Human	PMID:19158676
Cellular Component	GO:0061702	canonical inflammasome complex	PYCARD	IPI		Human	PMID:16037825
Cellular Component	GO:0061702	canonical inflammasome complex	Pycard	IDA		Mouse	PMID:30248149
Cellular Component	GO:0061702	canonical inflammasome complex	pycard	IPI	ZFIN:ZDB-GENE-120709-59,ZFIN:ZDB-GENE-000616-3	Zfish	PMID:30150286
Cellular Component	GO:0061702	canonical inflammasome complex	pycard	IPI	ZFIN:ZDB-GENE-020812-1,ZFIN:ZDB-GENE-120709-59	Zfish	PMID:30150286
Cellular Component	GO:0005737	cytoplasm	PYCARD	IDA		Human	PMID:14730312
Cellular Component	GO:0005737	cytoplasm	PYCARD	IDA		Human	PMID:15030775
Cellular Component	GO:0005737	cytoplasm	PYCARD	IDA		Human	PMID:19158679
Cellular Component	GO:0005829	cytosol	PYCARD	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	Pycard	IDA		Mouse	PMID:11139337
Cellular Component	GO:0005576	extracellular region	Pycard	IDA		Mouse	PMID:15190255
Cellular Component	GO:0000139	Golgi membrane	PYCARD	IDA		Human	PMID:23229815
Cellular Component	GO:0005739	mitochondrion	PYCARD	IDA		Human	PMID:14730312
Cellular Component	GO:0043025	neuronal cell body	Pycard	IDA		Rat	PMID:19401709|RGD:5491174
Cellular Component	GO:0072558	NLRP1 inflammasome complex	PYCARD	IPI		Human	PMID:17349957
Cellular Component	GO:0072558	NLRP1 inflammasome complex	PYCARD	IDA		Human	PMID:12191486
Cellular Component	GO:0072558	NLRP1 inflammasome complex	pycard	IDA		Zfish	PMID:30150286|ZFIN:ZDB-PUB-180829-2
Cellular Component	GO:0072558	NLRP1 inflammasome complex	pycard	IPI		Zfish	PMID:30150286|ZFIN:ZDB-PUB-180829-2
Cellular Component	GO:0072559	NLRP3 inflammasome complex	PYCARD	IPI		Human	PMID:29255148
Cellular Component	GO:0072559	NLRP3 inflammasome complex	PYCARD	IDA		Human	PMID:15030775
Cellular Component	GO:0072559	NLRP3 inflammasome complex	pycard	IDA		Zfish	PMID:31852739
Cellular Component	GO:0140738	NLRP6 inflammasome complex	PYCARD	IDA		Human	PMID:30674671
Cellular Component	GO:0140738	NLRP6 inflammasome complex	PYCARD	IDA		Human	PMID:34678144
Cellular Component	GO:0140738	NLRP6 inflammasome complex	Pycard	IDA		Mouse	MGI:MGI:6833928|PMID:34678144
Cellular Component	GO:0005730	nucleolus	PYCARD	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	PYCARD	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Pycard	IDA		Mouse	MGI:MGI:5621259|PMID:24407287
Cellular Component	GO:0005634	nucleus	Pycard	IDA		Mouse	MGI:MGI:5291858|PMID:21892172
Cellular Component	GO:0032991	protein-containing complex	PYCARD	IDA		Human	PMID:22267217
Cellular Component	GO:0032991	protein-containing complex	Pycard	IDA		Rat	PMID:19416975|RGD:5491011
Biological Process	GO:0097202	activation of cysteine-type endopeptidase activity	Pycard	IMP		Mouse	MGI:MGI:5491128|PMID:23302887
Biological Process	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	Pycard	IMP	MGI:MGI:3686870	Mouse	PMID:17008311
Biological Process	GO:0002218	activation of innate immune response	PYCARD	IDA		Human	PMID:21575908
Biological Process	GO:0002218	activation of innate immune response	Pycard	IMP		Mouse	MGI:MGI:3839029|PMID:19158675
Biological Process	GO:0071347	cellular response to interleukin-1	PYCARD	IDA		Human	PMID:12486103
Biological Process	GO:0071222	cellular response to lipopolysaccharide	PYCARD	IDA		Human	PMID:12486103
Biological Process	GO:0071356	cellular response to tumor necrosis factor	PYCARD	IDA		Human	PMID:12486103
Biological Process	GO:0042742	defense response to bacterium	pycard	IGI	ZFIN:ZDB-GENE-060531-46	Zfish	PMID:27363812
Biological Process	GO:0050829	defense response to Gram-negative bacterium	PYCARD	IMP		Human	PMID:16982856
Biological Process	GO:0050829	defense response to Gram-negative bacterium	PYCARD	IMP		Human	PMID:21487011
Biological Process	GO:0050830	defense response to Gram-positive bacterium	Pycard	IMP	MGI:MGI:3686870	Mouse	PMID:30248149
Biological Process	GO:0051607	defense response to virus	PYCARD	IDA		Human	PMID:21575908
Biological Process	GO:0006954	inflammatory response	Pycard	IMP	MGI:MGI:3046932	Mouse	PMID:15190255
Biological Process	GO:0045087	innate immune response	pycard	IGI	ZFIN:ZDB-MRPHLNO-170915-8,ZFIN:ZDB-MRPHLNO-180823-3	Zfish	PMID:29123523
Biological Process	GO:0032611	interleukin-1 beta production	Pycard	IGI	MGI:MGI:96544	Mouse	PMID:19158679
Biological Process	GO:0032611	interleukin-1 beta production	Pycard	IGI	MGI:MGI:2686159	Mouse	PMID:19158679
Biological Process	GO:0032611	interleukin-1 beta production	Pycard	IGI	MGI:MGI:107700	Mouse	PMID:22002608
Biological Process	GO:0032611	interleukin-1 beta production	Pycard	IGI	MGI:MGI:96543	Mouse	PMID:19158679
Biological Process	GO:0032611	interleukin-1 beta production	Pycard	IGI	MGI:MGI:2653833	Mouse	PMID:22002608
Biological Process	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator	PYCARD	IMP		Human	PMID:14730312
Biological Process	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	PYCARD	IMP		Human	PMID:14730312
Biological Process	GO:0010934	macrophage cytokine production	Pycard	IGI	MGI:MGI:2653833	Mouse	PMID:22002608
Biological Process	GO:0010934	macrophage cytokine production	Pycard	IGI	MGI:MGI:107700	Mouse	PMID:22002608
Biological Process	GO:0044351	macropinocytosis	Pycard	IMP		Mouse	MGI:MGI:5291858|PMID:21892172
Biological Process	GO:0001773	myeloid dendritic cell activation	PYCARD	IMP		Human	PMID:22732093
Biological Process	GO:0002277	myeloid dendritic cell activation involved in immune response	Pycard	IMP		Mouse	MGI:MGI:5291858|PMID:21892172
Biological Process	GO:1900016	negative regulation of cytokine production involved in inflammatory response	PYCARD	IMP		Human	PMID:24531343
Biological Process	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling	PYCARD	IDA		Human	PMID:12486103
Biological Process	GO:0032688	negative regulation of interferon-beta production	PYCARD	IMP		Human	PMID:19158675
Biological Process	GO:0032088	negative regulation of NF-kappaB transcription factor activity	PYCARD	IMP		Human	PMID:16585594
Biological Process	GO:0071901	negative regulation of protein serine/threonine kinase activity	PYCARD	IDA		Human	PMID:12486103
Biological Process	GO:0044546	NLRP3 inflammasome complex assembly	PYCARD	IDA		Human	PMID:27432880
Biological Process	GO:0030838	positive regulation of actin filament polymerization	Pycard	IMP		Mouse	MGI:MGI:5291858|PMID:21892172
Biological Process	GO:0042104	positive regulation of activated T cell proliferation	Pycard	IMP		Mouse	MGI:MGI:5291858|PMID:21892172
Biological Process	GO:0002821	positive regulation of adaptive immune response	PYCARD	IMP		Human	PMID:22732093
Biological Process	GO:0002588	positive regulation of antigen processing and presentation of peptide antigen via MHC class II	Pycard	IMP		Mouse	MGI:MGI:5291858|PMID:21892172
Biological Process	GO:0043065	positive regulation of apoptotic process	PYCARD	IDA		Human	PMID:12646168
Biological Process	GO:0032722	positive regulation of chemokine production	PYCARD	IMP		Human	PMID:21487011
Biological Process	GO:0032722	positive regulation of chemokine production	Pycard	IMP		Mouse	MGI:MGI:5448518|PMID:21487011
Biological Process	GO:2001056	positive regulation of cysteine-type endopeptidase activity	PYCARD	IDA		Human	PMID:19158676
Biological Process	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	PYCARD	IDA		Human	PMID:15030775
Biological Process	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	PYCARD	IMP		Human	PMID:22267217
Biological Process	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	Pycard	IMP		Rat	PMID:19401709|RGD:5491174
Biological Process	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	pycard	IPI	ZFIN:ZDB-GENE-000616-3	Zfish	PMID:12464617
Biological Process	GO:0002230	positive regulation of defense response to virus by host	Pycard	IMP		Mouse	MGI:MGI:3839029|PMID:19158675
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	PYCARD	IDA		Human	PMID:19494289
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	PYCARD	IMP		Human	PMID:21487011
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	Pycard	IMP		Mouse	MGI:MGI:5448518|PMID:21487011
Biological Process	GO:2001238	positive regulation of extrinsic apoptotic signaling pathway	PYCARD	IDA		Human	PMID:16964285
Biological Process	GO:0050729	positive regulation of inflammatory response	PYCARD	IDA		Human	PMID:12191486
Biological Process	GO:0050729	positive regulation of inflammatory response	Pycard	IDA		Mouse	MGI:MGI:6141801|PMID:27270401
Biological Process	GO:0032731	positive regulation of interleukin-1 beta production	PYCARD	IDA		Human	PMID:15030775
Biological Process	GO:0032731	positive regulation of interleukin-1 beta production	PYCARD	IDA		Human	PMID:16037825
Biological Process	GO:0032731	positive regulation of interleukin-1 beta production	PYCARD	IMP		Human	PMID:22267217
Biological Process	GO:0032731	positive regulation of interleukin-1 beta production	PYCARD	IDA		Human	PMID:24630722
Biological Process	GO:0032731	positive regulation of interleukin-1 beta production	PYCARD	IDA		Human	PMID:7642516
Biological Process	GO:0032731	positive regulation of interleukin-1 beta production	Pycard	IDA		Mouse	MGI:MGI:6141801|PMID:27270401
Biological Process	GO:0032731	positive regulation of interleukin-1 beta production	Pycard	IDA		Mouse	MGI:MGI:6112461|PMID:29255148
Biological Process	GO:0032731	positive regulation of interleukin-1 beta production	Pycard	IMP		Mouse	MGI:MGI:3839029|PMID:19158675
Biological Process	GO:0032731	positive regulation of interleukin-1 beta production	Pycard	IGI	MGI:MGI:2653833	Mouse	PMID:22002608
Biological Process	GO:0032731	positive regulation of interleukin-1 beta production	Pycard	IGI	MGI:MGI:107700	Mouse	PMID:22002608
Biological Process	GO:0032731	positive regulation of interleukin-1 beta production	Pycard	IMP	MGI:MGI:3686870	Mouse	PMID:23997220
Biological Process	GO:0032733	positive regulation of interleukin-10 production	PYCARD	IMP		Human	PMID:16982856
Biological Process	GO:0032755	positive regulation of interleukin-6 production	PYCARD	IMP		Human	PMID:16982856
Biological Process	GO:0032755	positive regulation of interleukin-6 production	Pycard	IMP		Mouse	MGI:MGI:5291858|PMID:21892172
Biological Process	GO:0032757	positive regulation of interleukin-8 production	PYCARD	IMP		Human	PMID:16982856
Biological Process	GO:0046330	positive regulation of JNK cascade	PYCARD	IMP		Human	PMID:21487011
Biological Process	GO:0060907	positive regulation of macrophage cytokine production	Pycard	IGI	MGI:MGI:107700	Mouse	PMID:22002608
Biological Process	GO:0060907	positive regulation of macrophage cytokine production	Pycard	IGI	MGI:MGI:2653833	Mouse	PMID:22002608
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	PYCARD	IDA		Human	PMID:12646168
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	PYCARD	IDA		Human	PMID:12656673
Biological Process	GO:1901224	positive regulation of NIK/NF-kappaB signaling	PYCARD	IPI	UniProtKB:Q96P20	Human	PMID:15817483
Biological Process	GO:0050766	positive regulation of phagocytosis	Pycard	IMP		Mouse	MGI:MGI:5291858|PMID:21892172
Biological Process	GO:0090200	positive regulation of release of cytochrome c from mitochondria	PYCARD	IDA		Human	PMID:14730312
Biological Process	GO:0050870	positive regulation of T cell activation	PYCARD	IMP		Human	PMID:22732093
Biological Process	GO:2000406	positive regulation of T cell migration	Pycard	IMP		Mouse	MGI:MGI:5291858|PMID:21892172
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	PYCARD	IMP		Human	PMID:16982856
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	PYCARD	IMP		Human	PMID:21487011
Biological Process	GO:0032729	positive regulation of type II interferon production	Pycard	IMP		Mouse	MGI:MGI:5291858|PMID:21892172
Biological Process	GO:0051260	protein homooligomerization	PYCARD	IDA		Human	PMID:24531343
Biological Process	GO:0042981	regulation of apoptotic process	Pycard	IMP	MGI:MGI:3046932	Mouse	PMID:15190255
Biological Process	GO:0010506	regulation of autophagy	Pycard	IMP	MGI:MGI:3686870	Mouse	PMID:24581500
Biological Process	GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process	Pycard	IMP	MGI:MGI:3046932	Mouse	PMID:15190255
Biological Process	GO:0043087	regulation of GTPase activity	Pycard	IMP		Mouse	MGI:MGI:5291858|PMID:21892172
Biological Process	GO:0050727	regulation of inflammatory response	Pycard	IMP	MGI:MGI:3686870	Mouse	PMID:22297845
Biological Process	GO:0050727	regulation of inflammatory response	Pycard	IMP	MGI:MGI:3686870	Mouse	PMID:22002608
Biological Process	GO:2001242	regulation of intrinsic apoptotic signaling pathway	PYCARD	IDA		Human	PMID:14730312
Biological Process	GO:0031647	regulation of protein stability	Pycard	IMP		Mouse	MGI:MGI:5291858|PMID:21892172
Biological Process	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway	PYCARD	IMP		Human	PMID:14730312
Biological Process	GO:0009617	response to bacterium	Pycard	IMP	MGI:MGI:3686870	Mouse	PMID:24581500
Biological Process	GO:0033209	tumor necrosis factor-mediated signaling pathway	PYCARD	IDA		Human	PMID:12656673

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern