Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RAB1A
  • Mouse genes Rab1a
  • Rat genes Rab1a
  • Zfish genes rab1aa,rab1ab
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rab1a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045296	cadherin binding	RAB1A	HDA		Human	PMID:25468996
Molecular Function	GO:0005525	GTP binding	Rab1a	IDA		Rat	PMID:8807639|RGD:2306441
Molecular Function	GO:0003924	GTPase activity	RAB1A	IDA		Human	PMID:17684057
Molecular Function	GO:0003924	GTPase activity	RAB1A	IDA		Human	PMID:22939626
Molecular Function	GO:0005515	protein binding	RAB1A	IPI	UniProtKB:P26374	Human	PMID:15186776
Molecular Function	GO:0005515	protein binding	RAB1A	IPI	UniProtKB:Q8N2Y8	Human	PMID:15796781
Molecular Function	GO:0005515	protein binding	RAB1A	IPI	UniProtKB:Q01968	Human	PMID:16902405
Molecular Function	GO:0005515	protein binding	RAB1A	IPI	UniProtKB:Q96BZ9	Human	PMID:17684057
Molecular Function	GO:0005515	protein binding	RAB1A	IPI	UniProtKB:P31150	Human	PMID:19942850
Molecular Function	GO:0005515	protein binding	RAB1A	IPI	UniProtKB:Q5ZSQ3	Human	PMID:19942850
Molecular Function	GO:0005515	protein binding	RAB1A	IPI	UniProtKB:Q01968	Human	PMID:25107275
Molecular Function	GO:0005515	protein binding	RAB1A	IPI	UniProtKB:P42345	Human	PMID:25446900
Molecular Function	GO:0005515	protein binding	RAB1A	IPI	UniProtKB:Q8N122	Human	PMID:25446900
Molecular Function	GO:0005515	protein binding	RAB1A	IPI	UniProtKB:P31150	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	RAB1A	IPI	UniProtKB:Q96LT7-1	Human	PMID:27334615
Molecular Function	GO:0005515	protein binding	RAB1A	IPI	UniProtKB:Q96LT7-2	Human	PMID:27334615
Molecular Function	GO:0005515	protein binding	RAB1A	IPI	UniProtKB:P31150	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	RAB1A	IPI	UniProtKB:P47224	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Rab1a	IPI	UniProtKB:Q6DFW0	Mouse	MGI:MGI:5553382|PMID:24549040
Cellular Component	GO:0005769	early endosome	Rab1a	IDA		Rat	PMID:21303926|RGD:8554665
Cellular Component	GO:0005789	endoplasmic reticulum membrane	Rab1a	IDA		Rat	PMID:8807639|RGD:2306441
Cellular Component	GO:0070062	extracellular exosome	RAB1A	HDA		Human	PMID:20458337
Cellular Component	GO:0005794	Golgi apparatus	RAB1A	HDA		Human	PMID:16791210
Cellular Component	GO:0005794	Golgi apparatus	Rab1a	IDA		Mouse	PMID:11042173
Cellular Component	GO:0000139	Golgi membrane	Rab1a	IDA		Rat	PMID:8807639|RGD:2306441
Cellular Component	GO:0042470	melanosome	Rab1a	IDA		Mouse	MGI:MGI:5526918|PMID:22854043
Cellular Component	GO:0043025	neuronal cell body	Rab1a	IDA		Rat	PMID:8573789|RGD:2306440
Cellular Component	GO:0098793	presynapse	Rab1a	EXP		Rat	PMID:23622064|RGD:13702180
Cellular Component	GO:0098793	presynapse	Rab1a	IDA		Rat	PMID:23622064|RGD:13702180
Cellular Component	GO:0098793	presynapse	Rab1a	IDA		Rat	PMID:20926670|RGD:13432355
Biological Process	GO:0000045	autophagosome assembly	RAB1A	IMP		Human	PMID:22939626
Biological Process	GO:0006914	autophagy	RAB1A	IMP		Human	PMID:22939626
Biological Process	GO:0016477	cell migration	RAB1A	IMP		Human	PMID:20639577
Biological Process	GO:0016477	cell migration	Rab1a	IMP		Mouse	MGI:MGI:5526933|PMID:20639577
Biological Process	GO:0090110	COPII-coated vesicle cargo loading	RAB1A	IMP		Human	PMID:17684057
Biological Process	GO:0042742	defense response to bacterium	RAB1A	IMP		Human	PMID:22939626
Biological Process	GO:0006897	endocytosis	RAB1A	IMP		Human	PMID:21303926
Biological Process	GO:0006897	endocytosis	Rab1a	IMP		Rat	PMID:21303926|RGD:8554665
Biological Process	GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	RAB1A	IMP		Human	PMID:17684057
Biological Process	GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	RAB1A	IGI	UniProtKB:Q9H0U4	Human	PMID:21680502
Biological Process	GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	RAB1A	IMP		Human	PMID:21680502
Biological Process	GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	RAB1A	IMP		Human	PMID:22939626
Biological Process	GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	Rab1a	IDA		Rat	PMID:15728249|RGD:8554056
Biological Process	GO:0007030	Golgi organization	RAB1A	IMP		Human	PMID:17684057
Biological Process	GO:0007030	Golgi organization	RAB1A	IMP		Human	PMID:26209634
Biological Process	GO:0030252	growth hormone secretion	RAB1A	IMP		Human	PMID:22939626
Biological Process	GO:0032402	melanosome transport	Rab1a	IMP		Mouse	MGI:MGI:5526918|PMID:22854043
Biological Process	GO:1903020	positive regulation of glycoprotein metabolic process	RAB1A	IGI	UniProtKB:Q9H0U4	Human	PMID:21680502
Biological Process	GO:0032757	positive regulation of interleukin-8 production	RAB1A	IMP		Human	PMID:22939626
Biological Process	GO:0034446	substrate adhesion-dependent cell spreading	Rab1a	IMP		Mouse	MGI:MGI:5526933|PMID:20639577
Biological Process	GO:0047496	vesicle transport along microtubule	RAB1A	IMP		Human	PMID:21303926
Biological Process	GO:0047496	vesicle transport along microtubule	Rab1a	IMP		Rat	PMID:21303926|RGD:8554665
Biological Process	GO:0019068	virion assembly	RAB1A	IGI	UniProtKB:Q9H0U4	Human	PMID:21680502
Biological Process	GO:0019068	virion assembly	RAB1A	IMP		Human	PMID:21680502

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern