Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RAB25
  • Mouse genes Rab25
  • Rat genes Rab25
  • Zfish genes rab25a,rab25b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rab25

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0031489	myosin V binding	RAB25	IPI	UniProtKB:Q9Y4I1	Human	PMID:24006491
Molecular Function	GO:0005515	protein binding	RAB25	IPI	UniProtKB:P05556	Human	PMID:17925226
Molecular Function	GO:0005515	protein binding	RAB25	IPI	UniProtKB:P06756	Human	PMID:17925226
Molecular Function	GO:0005515	protein binding	RAB25	IPI	UniProtKB:P08563:PRO_0000041303	Human	PMID:24955142
Molecular Function	GO:0005515	protein binding	RAB25	IPI	UniProtKB:Q9H267	Human	PMID:28017832
Molecular Function	GO:0005515	protein binding	RAB25	IPI	UniProtKB:Q7L804	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RAB25	IPI	UniProtKB:Q7L8J4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RAB25	IPI	UniProtKB:Q9ULV0-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Rab25	IPI	PR:Q9CXU1	Mouse	PMID:11591653
Cellular Component	GO:0031410	cytoplasmic vesicle	RAB25	IDA		Human	PMID:17925226
Cellular Component	GO:0031410	cytoplasmic vesicle	RAB25	IDA		Human	PMID:22613965
Cellular Component	GO:0070062	extracellular exosome	RAB25	HDA		Human	PMID:19056867
Cellular Component	GO:0005886	plasma membrane	RAB25	IDA		Human	GO_REF:0000052
Cellular Component	GO:0031143	pseudopodium	RAB25	IDA		Human	PMID:17925226
Biological Process	GO:0030866	cortical actin cytoskeleton organization	rab25a	IMP	ZFIN:ZDB-GENO-220321-1	Zfish	PMID:33755014
Biological Process	GO:0030866	cortical actin cytoskeleton organization	rab25b	IMP	ZFIN:ZDB-GENO-220321-3	Zfish	PMID:33755014
Biological Process	GO:0030866	cortical actin cytoskeleton organization	rab25a	IMP	ZFIN:ZDB-GENO-220321-2	Zfish	PMID:33755014
Biological Process	GO:0003382	epithelial cell morphogenesis	Rab25	IMP		Mouse	MGI:MGI:5499697|PMID:22696678
Biological Process	GO:0008284	positive regulation of cell population proliferation	RAB25	IDA		Human	PMID:15502842
Biological Process	GO:0010634	positive regulation of epithelial cell migration	RAB25	IMP		Human	PMID:22613965
Biological Process	GO:0031268	pseudopodium organization	RAB25	IDA		Human	PMID:17925226
Biological Process	GO:0032465	regulation of cytokinesis	rab25a	IMP	ZFIN:ZDB-GENO-220321-2	Zfish	PMID:33755014
Biological Process	GO:0032465	regulation of cytokinesis	rab25b	IMP	ZFIN:ZDB-GENO-220321-3	Zfish	PMID:33755014
Biological Process	GO:0032465	regulation of cytokinesis	rab25a	IMP	ZFIN:ZDB-GENO-220321-1	Zfish	PMID:33755014
Biological Process	GO:2001135	regulation of endocytic recycling	rab25a	IMP	ZFIN:ZDB-GENO-220321-2	Zfish	PMID:33755014
Biological Process	GO:2001135	regulation of endocytic recycling	rab25b	IMP	ZFIN:ZDB-GENO-220321-3	Zfish	PMID:33755014
Biological Process	GO:2001135	regulation of endocytic recycling	rab25a	IMP	ZFIN:ZDB-GENO-220321-1	Zfish	PMID:33755014
Biological Process	GO:0060627	regulation of vesicle-mediated transport	RAB25	IMP		Human	PMID:22613965

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern