Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RAB34
  • Mouse genes Rab34
  • Rat genes Rab34
  • Zfish genes rab34a,rab34b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rab34

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0030742	GTP-dependent protein binding	RAB34	IPI	UniProtKB:O14795	Human	PMID:16138900
Molecular Function	GO:0003924	GTPase activity	Rab34	IDA		Mouse	PMID:12446704
Molecular Function	GO:0019001	guanyl nucleotide binding	Rab34	IDA		Mouse	PMID:12446704
Molecular Function	GO:0005515	protein binding	RAB34	IPI	UniProtKB:O14795	Human	PMID:16138900
Molecular Function	GO:0005515	protein binding	RAB34	IPI	UniProtKB:P35219	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	Rab34	IPI	PR:Q5ND29	Mouse	PMID:22275436
Molecular Function	GO:0031267	small GTPase binding	RAB34	IPI	UniProtKB:P11233	Human	PMID:24056301
Cellular Component	GO:0031410	cytoplasmic vesicle	Rab34	IDA		Mouse	MGI:MGI:5467668|PMID:23197834
Cellular Component	GO:0005769	early endosome	Rab34	IDA		Mouse	PMID:12446704
Cellular Component	GO:0070062	extracellular exosome	RAB34	HDA		Human	PMID:19056867
Cellular Component	GO:0005794	Golgi apparatus	RAB34	IDA		Human	PMID:16138900
Cellular Component	GO:0005794	Golgi apparatus	Rab34	IDA		Mouse	MGI:MGI:5467668|PMID:23197834
Cellular Component	GO:0031985	Golgi cisterna	RAB34	IDA		Human	PMID:17881736
Cellular Component	GO:0005795	Golgi stack	RAB34	IDA		Human	PMID:17881736
Cellular Component	GO:0005770	late endosome	Rab34	IDA		Mouse	MGI:MGI:5467668|PMID:23197834
Cellular Component	GO:0048471	perinuclear region of cytoplasm	RAB34	IDA		Human	PMID:16138900
Cellular Component	GO:0045335	phagocytic vesicle	RAB34	IDA		Human	PMID:21255211
Cellular Component	GO:0045335	phagocytic vesicle	Rab34	IDA		Mouse	MGI:MGI:5467668|PMID:23197834
Cellular Component	GO:0001726	ruffle	Rab34	IDA		Mouse	PMID:12446704
Cellular Component	GO:0031982	vesicle	RAB34	IDA		Human	PMID:17881736
Biological Process	GO:0019882	antigen processing and presentation	RAB34	IMP		Human	PMID:19717423
Biological Process	GO:0071333	cellular response to glucose stimulus	Rab34	IMP		Rat	PMID:19641095|RGD:11535114
Biological Process	GO:0006897	endocytosis	Rab34	IDA		Mouse	PMID:12446704
Biological Process	GO:0043001	Golgi to plasma membrane protein transport	RAB34	IDA		Human	PMID:17881736
Biological Process	GO:0043001	Golgi to plasma membrane protein transport	Rab34	IGI	UniProtKB:Q9BZG1	Mouse	MGI:MGI:5545997|PMID:17881736
Biological Process	GO:0007041	lysosomal transport	Rab34	IDA		Mouse	MGI:MGI:5467668|PMID:23197834
Biological Process	GO:0032418	lysosome localization	RAB34	IDA		Human	PMID:17881736
Biological Process	GO:0090382	phagosome maturation	RAB34	IMP		Human	PMID:21255211
Biological Process	GO:0090385	phagosome-lysosome fusion	RAB34	IMP		Human	PMID:21255211
Biological Process	GO:0090385	phagosome-lysosome fusion	Rab34	IMP		Mouse	MGI:MGI:5467668|PMID:23197834
Biological Process	GO:1900426	positive regulation of defense response to bacterium	Rab34	IDA		Mouse	MGI:MGI:5467668|PMID:23197834
Biological Process	GO:1905171	positive regulation of protein localization to phagocytic vesicle	Rab34	IMP		Mouse	MGI:MGI:5467668|PMID:23197834
Biological Process	GO:0050714	positive regulation of protein secretion	Rab34	IMP		Rat	PMID:19641095|RGD:11535114
Biological Process	GO:0045880	positive regulation of smoothened signaling pathway	Rab34	IMP		Mouse	MGI:MGI:6111022|PMID:29290584
Biological Process	GO:0072659	protein localization to plasma membrane	RAB34	IDA		Human	PMID:17881736

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern