Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RAB3A
  • Mouse genes Rab3a
  • Rat genes Rab3a
  • Zfish genes rab3aa,rab3ab
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rab3a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001671	ATPase activator activity	Rab3a	IDA		Rat	PMID:11062069|RGD:633463
Molecular Function	GO:0051117	ATPase binding	Rab3a	IPI	RGD:621594	Rat	PMID:11062069|RGD:633463
Molecular Function	GO:0051021	GDP-dissociation inhibitor binding	Rab3a	IPI	RGD:2676	Rat	PMID:12426384|RGD:632546
Molecular Function	GO:0005525	GTP binding	Rab3a	IDA		Rat	PMID:8807639|RGD:2306441
Molecular Function	GO:0030742	GTP-dependent protein binding	Rab3a	IPI	PR:P35276	Mouse	PMID:21262767
Molecular Function	GO:0003924	GTPase activity	RAB3A	IMP		Human	PMID:10859313
Molecular Function	GO:0003924	GTPase activity	RAB3A	IDA		Human	PMID:24891604
Molecular Function	GO:0031489	myosin V binding	RAB3A	IPI	UniProtKB:Q9Y4I1	Human	PMID:24006491
Molecular Function	GO:0005515	protein binding	RAB3A	IPI	UniProtKB:Q15042	Human	PMID:10859313
Molecular Function	GO:0005515	protein binding	RAB3A	IPI	UniProtKB:P37840	Human	PMID:15207266
Molecular Function	GO:0005515	protein binding	RAB3A	IPI	UniProtKB:Q9Y2J0	Human	PMID:15207266
Molecular Function	GO:0005515	protein binding	RAB3A	IPI	UniProtKB:Q15042	Human	PMID:24891604
Molecular Function	GO:0005515	protein binding	RAB3A	IPI	UniProtKB:P47224	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RAB3A	IPI	UniProtKB:Q96QF0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RAB3A	IPI	UniProtKB:P35579	Human	PMID:2732579
Molecular Function	GO:0005515	protein binding	RAB3A	IPI	UniProtKB:P35579	Human	PMID:27325790
Molecular Function	GO:0005515	protein binding	RAB3A	IPI	UniProtKB:P47224	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RAB3A	IPI	UniProtKB:P60410	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RAB3A	IPI	UniProtKB:Q8TBN0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RAB3A	IPI	UniProtKB:Q96QF0-7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RAB3A	IPI	UniProtKB:Q9H8Y1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Rab3a	IPI	UniProtKB:P47708	Mouse	MGI:MGI:2176311|PMID:11773082
Molecular Function	GO:0005515	protein binding	Rab3a	IPI	UniProtKB:Q8TDW5	Mouse	MGI:MGI:4942255|PMID:12051743
Molecular Function	GO:0005515	protein binding	Rab3a	IPI	UniProtKB:P47708	Mouse	MGI:MGI:4839453|PMID:14722103
Molecular Function	GO:0005515	protein binding	Rab3a	IPI	UniProtKB:Q9JIR4	Mouse	MGI:MGI:3652690|PMID:16782817
Molecular Function	GO:0005515	protein binding	Rab3a	IPI	UniProtKB:Q768S4	Mouse	MGI:MGI:3653776|PMID:11598194
Molecular Function	GO:0005515	protein binding	Rab3a	IPI	UniProtKB:P63011|UniProtKB:Q9R0Q1	Mouse	MGI:MGI:2176311|PMID:11773082
Molecular Function	GO:0005515	protein binding	Rab3a	IPI	PR:Q768S4	Mouse	PMID:15159548
Molecular Function	GO:0005515	protein binding	Rab3a	IPI	PR:Q9EQZ7	Mouse	PMID:12578829
Molecular Function	GO:0005515	protein binding	Rab3a	IPI	PR:Q9EQZ7	Mouse	PMID:11056535
Molecular Function	GO:0005515	protein binding	Rab3a	IPI	PR:Q768S4	Mouse	PMID:12578829
Molecular Function	GO:0005515	protein binding	Rab3a	IPI	UniProtKB:P47709	Rat	PMID:10025402|RGD:2314908
Molecular Function	GO:0005515	protein binding	Rab3a	IPI	RGD:619764	Rat	PMID:11516400|RGD:632896
Molecular Function	GO:0005515	protein binding	Rab3a	IPI	UniProtKB:P47709	Rat	PMID:16763567|RGD:8553578
Molecular Function	GO:0005515	protein binding	Rab3a	IPI	UniProtKB:P61765	Rat	PMID:21689256|RGD:14390056
Molecular Function	GO:0005515	protein binding	Rab3a	IPI	UniProtKB:P21707	Rat	PMID:28057568|RGD:14390053
Molecular Function	GO:0005515	protein binding	Rab3a	IPI	RGD:620650	Rat	PMID:7532276|RGD:633748
Molecular Function	GO:0005515	protein binding	Rab3a	IPI	UniProtKB:Q62739	Rat	PMID:7532276|RGD:633748
Molecular Function	GO:0005515	protein binding	Rab3a	IPI	UniProtKB:P47709	Rat	PMID:8617225|RGD:14397552
Molecular Function	GO:0005515	protein binding	Rab3a	IPI	RGD:621002	Rat	PMID:9341137|RGD:633794
Molecular Function	GO:0030674	protein-macromolecule adaptor activity	Rab3a	IDA		Mouse	PMID:11056535
Cellular Component	GO:0001669	acrosomal vesicle	Rab3a	IDA		Mouse	PMID:21128978
Cellular Component	GO:0030424	axon	Rab3a	IDA		Rat	PMID:16141272|RGD:8693376
Cellular Component	GO:0005829	cytosol	Rab3a	IDA		Rat	PMID:10340764|RGD:4892571
Cellular Component	GO:0005768	endosome	Rab3a	IDA		Mouse	PMID:11182090
Cellular Component	GO:1903561	extracellular vesicle	RAB3A	HDA		Human	PMID:24769233
Cellular Component	GO:0043229	intracellular organelle	Rab3a	IDA		Rat	PMID:10340764|RGD:4892571
Cellular Component	GO:0016020	membrane	Rab3a	IDA		Rat	PMID:8807639|RGD:2306441
Cellular Component	GO:0048471	perinuclear region of cytoplasm	RAB3A	IDA		Human	PMID:27325790
Cellular Component	GO:0098794	postsynapse	Rab3a	IDA		Mouse	MGI:MGI:6451238|PMID:31651360
Cellular Component	GO:0098793	presynapse	Rab3a	IDA		Mouse	MGI:MGI:6451238|PMID:31651360
Cellular Component	GO:0048786	presynaptic active zone	Rab3a	IDA		Mouse	MGI:MGI:3790159|PMID:18448650
Cellular Component	GO:0032991	protein-containing complex	Rab3a	IDA		Rat	PMID:12426384|RGD:632546
Cellular Component	GO:0030141	secretory granule	Rab3a	IDA		Rat	PMID:17311845|RGD:14390061
Cellular Component	GO:0008021	synaptic vesicle	Rab3a	IDA		Mouse	PMID:12167638
Cellular Component	GO:0008021	synaptic vesicle	Rab3a	IDA		Mouse	PMID:12192047
Cellular Component	GO:0008021	synaptic vesicle	Rab3a	IDA		Rat	PMID:16141272|RGD:8693376
Cellular Component	GO:0008021	synaptic vesicle	Rab3a	IDA		Rat	PMID:17110340|RGD:12050113
Cellular Component	GO:0008021	synaptic vesicle	Rab3a	IDA		Rat	PMID:8043272|RGD:2306269
Cellular Component	GO:0008021	synaptic vesicle	Rab3a	IDA		Rat	PMID:8617225|RGD:14397552
Cellular Component	GO:0030672	synaptic vesicle membrane	Rab3a	IDA		Mouse	PMID:12167638
Cellular Component	GO:0030672	synaptic vesicle membrane	Rab3a	IEP		Mouse	PMID:12167638
Cellular Component	GO:0030672	synaptic vesicle membrane	Rab3a	EXP		Rat	PMID:17110340|RGD:12050113
Cellular Component	GO:0030672	synaptic vesicle membrane	Rab3a	IDA		Rat	PMID:17110340|RGD:12050113
Cellular Component	GO:0030672	synaptic vesicle membrane	Rab3a	IDA		Rat	PMID:20926670|RGD:13432355
Cellular Component	GO:0043195	terminal bouton	Rab3a	IDA		Mouse	MGI:MGI:3652690|PMID:16782817
Cellular Component	GO:0043195	terminal bouton	Rab3a	IDA		Rat	PMID:16141272|RGD:8693376
Biological Process	GO:0060478	acrosomal vesicle exocytosis	RAB3A	IDA		Human	PMID:22248876
Biological Process	GO:0007409	axonogenesis	Rab3a	IMP	MGI:MGI:3762127	Mouse	PMID:11359932
Biological Process	GO:0017156	calcium-ion regulated exocytosis	Rab3a	IMP		Mouse	MGI:MGI:4830800|PMID:20338242
Biological Process	GO:0051649	establishment of localization in cell	Rab3a	IPI	PR:Q9EQZ7	Mouse	PMID:11056535
Biological Process	GO:0061670	evoked neurotransmitter secretion	Rab3a	IMP		Mouse	MGI:MGI:3653150|PMID:9194562
Biological Process	GO:0006887	exocytosis	RAB3A	IDA		Human	PMID:27325790
Biological Process	GO:0030073	insulin secretion	Rab3a	IPI	PR:Q9EQZ7	Mouse	PMID:11056535
Biological Process	GO:0030324	lung development	Rab3a	IMP	MGI:MGI:3762127	Mouse	PMID:11359932
Biological Process	GO:0032418	lysosome localization	RAB3A	IMP		Human	PMID:2732579
Biological Process	GO:0048790	maintenance of presynaptic active zone structure	Rab3a	IMP	MGI:MGI:3762127	Mouse	PMID:11359932
Biological Process	GO:0007005	mitochondrion organization	Rab3a	IMP	MGI:MGI:3762127	Mouse	PMID:11359932
Biological Process	GO:0007274	neuromuscular synaptic transmission	Rab3a	IMP	MGI:MGI:3762127	Mouse	PMID:11359932
Biological Process	GO:0001778	plasma membrane repair	RAB3A	IDA		Human	PMID:27325790
Biological Process	GO:1903307	positive regulation of regulated secretory pathway	RAB3A	IMP		Human	PMID:22899725
Biological Process	GO:0009791	post-embryonic development	Rab3a	IMP	MGI:MGI:3762127	Mouse	PMID:11359932
Biological Process	GO:0045055	regulated exocytosis	RAB3A	IMP		Human	PMID:2732579
Biological Process	GO:0014059	regulation of dopamine secretion	Rab3a	IDA		Rat	PMID:28370453|RGD:15023476
Biological Process	GO:0017157	regulation of exocytosis	Rab3a	IDA		Mouse	PMID:12167638
Biological Process	GO:1905684	regulation of plasma membrane repair	RAB3A	IMP		Human	PMID:2732579
Biological Process	GO:0099161	regulation of presynaptic dense core granule exocytosis	Rab3a	IDA		Mouse	PMID:31679900
Biological Process	GO:0099161	regulation of presynaptic dense core granule exocytosis	Rab3a	IMP		Mouse	PMID:31679900
Biological Process	GO:0048172	regulation of short-term neuronal synaptic plasticity	Rab3a	IMP		Mouse	MGI:MGI:3653150|PMID:9194562
Biological Process	GO:2000300	regulation of synaptic vesicle exocytosis	Rab3a	IDA		Rat	PMID:28057568|RGD:14390053
Biological Process	GO:0031630	regulation of synaptic vesicle fusion to presynaptic active zone membrane	Rab3a	IMP	MGI:MGI:3762127	Mouse	PMID:11359932
Biological Process	GO:0031630	regulation of synaptic vesicle fusion to presynaptic active zone membrane	Rab3a	IMP		Mouse	PMID:9194562
Biological Process	GO:0031630	regulation of synaptic vesicle fusion to presynaptic active zone membrane	Rab3a	IDA		Mouse	PMID:9194562
Biological Process	GO:0010807	regulation of synaptic vesicle priming	Rab3a	IDA		Rat	PMID:21689256|RGD:14390056
Biological Process	GO:0003016	respiratory system process	Rab3a	IMP	MGI:MGI:3762127	Mouse	PMID:11359932
Biological Process	GO:0051602	response to electrical stimulus	Rab3a	IMP	MGI:MGI:3762127	Mouse	PMID:11359932
Biological Process	GO:0050975	sensory perception of touch	Rab3a	IMP	MGI:MGI:3762127	Mouse	PMID:11359932
Biological Process	GO:0097091	synaptic vesicle clustering	Rab3a	IMP		Mouse	MGI:MGI:4830800|PMID:20338242
Biological Process	GO:0016079	synaptic vesicle exocytosis	Rab3a	IMP	MGI:MGI:3762127	Mouse	PMID:11359932
Biological Process	GO:0016079	synaptic vesicle exocytosis	Rab3a	IMP		Rat	PMID:16141272|RGD:8693376
Biological Process	GO:0016188	synaptic vesicle maturation	Rab3a	IMP	MGI:MGI:3762127	Mouse	PMID:11359932
Biological Process	GO:0036465	synaptic vesicle recycling	Rab3a	IMP		Rat	PMID:16141272|RGD:8693376
Biological Process	GO:0048489	synaptic vesicle transport	Rab3a	IDA		Mouse	MGI:MGI:3653776|PMID:11598194

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern