Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RAB5B
  • Mouse genes Rab5b
  • Rat genes Rab5b
  • Zfish genes rab5b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rab5b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019003	GDP binding	RAB5B	IDA		Human	PMID:20937701
Molecular Function	GO:0030742	GTP-dependent protein binding	RAB5B	IDA		Human	PMID:10491193
Molecular Function	GO:0003924	GTPase activity	RAB5B	IDA		Human	PMID:17562788
Molecular Function	GO:0005515	protein binding	RAB5B	IPI	UniProtKB:Q15075	Human	PMID:10491193
Molecular Function	GO:0005515	protein binding	RAB5B	IPI	UniProtKB:Q96HU1	Human	PMID:17562788
Molecular Function	GO:0005515	protein binding	RAB5B	IPI	UniProtKB:Q5S007	Human	PMID:18445495
Molecular Function	GO:0005515	protein binding	RAB5B	IPI	UniProtKB:Q5S007	Human	PMID:25605758
Molecular Function	GO:0005515	protein binding	RAB5B	IPI	UniProtKB:Q5S007	Human	PMID:27314038
Molecular Function	GO:0005515	protein binding	RAB5B	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	RAB5B	IPI	UniProtKB:Q8N612	Human	PMID:34882091
Molecular Function	GO:0005515	protein binding	Rab5b	IPI	UniProtKB:Q5S007	Mouse	MGI:MGI:5516187|PMID:18445495
Cellular Component	GO:0030139	endocytic vesicle	Rab5b	IDA		Mouse	PMID:7789520
Cellular Component	GO:0005768	endosome	RAB5B	IDA		Human	PMID:10491193
Cellular Component	GO:0070062	extracellular exosome	RAB5B	IDA		Human	PMID:15326289
Cellular Component	GO:0070062	extracellular exosome	RAB5B	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	RAB5B	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	RAB5B	HDA		Human	PMID:23533145
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	RAB5B	IDA		Human	GO_REF:0000052
Cellular Component	GO:0030672	synaptic vesicle membrane	Rab5b	EXP		Rat	PMID:20926670|RGD:13432355
Cellular Component	GO:0030672	synaptic vesicle membrane	Rab5b	IDA		Rat	PMID:20926670|RGD:13432355
Biological Process	GO:0019882	antigen processing and presentation	RAB5B	IMP		Human	PMID:19717423
Biological Process	GO:0007032	endosome organization	Rab5b	IDA		Mouse	PMID:7789520
Biological Process	GO:0048227	plasma membrane to endosome transport	RAB5B	IMP		Human	PMID:17562788
Biological Process	GO:0030100	regulation of endocytosis	Rab5b	IDA		Mouse	PMID:7789520

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern