Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RAB7B
  • Mouse genes Rab7b
  • Rat genes Rab7b
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rab7b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	RAB7B	IPI	UniProtKB:Q92624	Human	PMID:32296183
Cellular Component	GO:0005794	Golgi apparatus	RAB7B	IDA		Human	PMID:20375062
Cellular Component	GO:0005770	late endosome	RAB7B	IDA		Human	PMID:20375062
Cellular Component	GO:0005770	late endosome	Rab7b	IDA		Mouse	MGI:MGI:3834524|PMID:17395780
Cellular Component	GO:0005770	late endosome	Rab7b	IDA		Mouse	MGI:MGI:4355098|PMID:19587007
Cellular Component	GO:0005764	lysosome	RAB7B	IDA		Human	PMID:20375062
Cellular Component	GO:0005764	lysosome	Rab7b	IDA		Mouse	MGI:MGI:4355098|PMID:19587007
Cellular Component	GO:0005764	lysosome	Rab7b	IDA		Mouse	MGI:MGI:3834524|PMID:17395780
Cellular Component	GO:0045335	phagocytic vesicle	RAB7B	IDA		Human	PMID:21255211
Cellular Component	GO:0045335	phagocytic vesicle	Rab7b	IDA		Mouse	PMID:19144319
Cellular Component	GO:0005802	trans-Golgi network	RAB7B	IDA		Human	PMID:20375062
Biological Process	GO:0071346	cellular response to type II interferon	Rab7b	IDA		Mouse	PMID:19144319
Biological Process	GO:0034499	late endosome to Golgi transport	RAB7B	IMP		Human	PMID:20375062
Biological Process	GO:0034144	negative regulation of toll-like receptor 4 signaling pathway	Rab7b	IMP		Mouse	MGI:MGI:3834524|PMID:17395780
Biological Process	GO:0034164	negative regulation of toll-like receptor 9 signaling pathway	Rab7b	IMP		Mouse	MGI:MGI:4355098|PMID:19587007
Biological Process	GO:0032755	positive regulation of interleukin-6 production	RAB7B	IMP		Human	PMID:20953574
Biological Process	GO:0045654	positive regulation of megakaryocyte differentiation	RAB7B	IMP		Human	PMID:20953574
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	RAB7B	IMP		Human	PMID:20953574

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern