Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RAC1
  • Mouse genes Rac1
  • Rat genes Rac1
  • Zfish genes rac1a,rac1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rac1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051117	ATPase binding	Rac1	IPI	RGD:2179	Rat	PMID:20671235|RGD:11341707
Molecular Function	GO:0019899	enzyme binding	RAC1	IPI	UniProtKB:Q9Y5S8	Human	PMID:16636067
Molecular Function	GO:0005525	GTP binding	RAC1	IDA		Human	PMID:12551911
Molecular Function	GO:0005525	GTP binding	RAC1	IDA		Human	PMID:15467718
Molecular Function	GO:0005525	GTP binding	RAC1	IDA		Human	PMID:15601624
Molecular Function	GO:0005525	GTP binding	RAC1	IMP		Human	PMID:19625648
Molecular Function	GO:0005525	GTP binding	RAC1	IDA		Human	PMID:22036506
Molecular Function	GO:0005525	GTP binding	RAC1	IDA		Human	PMID:23620790
Molecular Function	GO:0005525	GTP binding	Rac1	IDA		Mouse	PMID:15728191
Molecular Function	GO:0005525	GTP binding	Rac1	IDA		Mouse	PMID:12783890
Molecular Function	GO:0005525	GTP binding	Rac1	IDA		Mouse	PMID:23528453
Molecular Function	GO:0005525	GTP binding	Rac1	IDA		Mouse	PMID:14580336
Molecular Function	GO:0005525	GTP binding	Rac1	IDA		Rat	PMID:12672819|RGD:704329
Molecular Function	GO:0005525	GTP binding	Rac1	IDA		Rat	PMID:15788770|RGD:2314386
Molecular Function	GO:0030742	GTP-dependent protein binding	Rac1	IPI	UniProtKB:Q9Z101	Mouse	MGI:MGI:3687818|PMID:10954424
Molecular Function	GO:0003924	GTPase activity	RAC1	IDA		Human	PMID:19787194
Molecular Function	GO:0003924	GTPase activity	RAC1	IDA		Human	PMID:27917469
Molecular Function	GO:0003924	GTPase activity	Rac1	IDA		Mouse	PMID:10699171
Molecular Function	GO:0003924	GTPase activity	Rac1	IDA		Mouse	PMID:12525493
Molecular Function	GO:0003924	GTPase activity	Rac1	IDA		Mouse	PMID:15249579
Molecular Function	GO:0003924	GTPase activity	Rac1	IDA		Rat	PMID:12672819|RGD:704329
Molecular Function	GO:0042826	histone deacetylase binding	Rac1	IPI	RGD:619977	Rat	PMID:22679019|RGD:9590167
Molecular Function	GO:0060090	molecular adaptor activity	RAC1	IPI	UniProtKB:O60331	Human	PMID:12874273
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:P21333	Human	PMID:10051605
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q13153	Human	PMID:11030651
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:P41743	Human	PMID:11260256
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q9BYG4	Human	PMID:11260256
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q9BYG5	Human	PMID:11260256
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q9NPB6	Human	PMID:11260256
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:P53365	Human	PMID:11346801
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:P52565	Human	PMID:11513578
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q9UQB8	Human	PMID:11696321
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:O14713	Human	PMID:11807099
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q14185	Human	PMID:12134158
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q92608	Human	PMID:12134158
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:O60331	Human	PMID:12874273
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q13153	Human	PMID:12879077
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q01968	Human	PMID:12915445
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q9P258	Human	PMID:12919680
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q96F07	Human	PMID:15048733
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q14185	Human	PMID:15247908
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q14185	Human	PMID:15723800
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q92608	Human	PMID:15723800
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q13153	Human	PMID:16492808
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q14155	Human	PMID:16492808
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:P52757	Human	PMID:16628218
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q86UR1	Human	PMID:16636067
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q9GSG9	Human	PMID:16968699
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q9UQB8	Human	PMID:17003044
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q96N96	Human	PMID:17145773
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:P52565	Human	PMID:17245428
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q01105	Human	PMID:17245428
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q13153	Human	PMID:17245428
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:P15498	Human	PMID:18511940
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:P46940	Human	PMID:18809683
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q9UQB8	Human	PMID:19171758
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:P19174	Human	PMID:19264842
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q13177	Human	PMID:19264842
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:O75369	Human	PMID:19270716
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q13153	Human	PMID:19270716
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:P16144	Human	PMID:19403692
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q13153	Human	PMID:19596003
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q13153	Human	PMID:19732720
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:O43157	Human	PMID:19843518
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q9H9P5	Human	PMID:20148946
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q99755	Human	PMID:20660631
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q5VV41	Human	PMID:20679435
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q13177	Human	PMID:20696164
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q7Z6J0	Human	PMID:20696164
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q8TEJ3	Human	PMID:20696164
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q13153	Human	PMID:20810653
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q765P7	Human	PMID:20875796
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q13153	Human	PMID:20936779
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q13177	Human	PMID:20936779
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q7Z6J0	Human	PMID:20936779
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q16513	Human	PMID:20974804
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q13153	Human	PMID:21029865
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q13153	Human	PMID:21167153
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q13153	Human	PMID:21454543
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q5S007	Human	PMID:21454543
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:P52565	Human	PMID:21900206
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:P53365	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q8IYU2	Human	PMID:22036506
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:P98170	Human	PMID:22117219
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q13153	Human	PMID:22117219
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q13490	Human	PMID:22117219
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:P52565	Human	PMID:22157745
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q13153	Human	PMID:22581261
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q03135	Human	PMID:22614015
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q8IYU2	Human	PMID:22614015
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q13177	Human	PMID:22705156
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q60838	Human	PMID:23109420
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q92997	Human	PMID:23109420
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q01105	Human	PMID:23195690
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:F1LYQ8	Human	PMID:23209303
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:P46940	Human	PMID:23982733
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q92619	Human	PMID:24086303
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q13153	Human	PMID:24172987
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q98PK8	Human	PMID:24172987
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q6P589	Human	PMID:24274578
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q03135	Human	PMID:24625804
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q13153	Human	PMID:24625804
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q13153	Human	PMID:24792722
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q14155	Human	PMID:24792722
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q6A162	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q9BRK4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q9UJX2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q9Y6N9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:P05412	Human	PMID:25609649
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q13153	Human	PMID:25843002
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q13153	Human	PMID:26175416
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:P46940	Human	PMID:27173435
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:P52565	Human	PMID:27173435
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:P46940	Human	PMID:28007913
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q92963	Human	PMID:29734338
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:P53365	Human	PMID:29997244
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q9NUQ9	Human	PMID:30250061
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q9NUQ9	Human	PMID:31285585
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:P53365	Human	PMID:31467278
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:O15063	Human	PMID:31871319
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:P46940	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:P52565	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q8WUI4-6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q99750	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q13177	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:O60784-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:P00491	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:P04271	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:P05412	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:P27986-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:P41227	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:P43405-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q06547-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q13387-4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q14457	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q8N5Z5	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q8WTV1	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q96JM7-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q9BVJ6	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q9NY61	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q9UBQ0-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q9UHV9	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q15311	Human	PMID:7673236
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:P42768	Human	PMID:8625410
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:P53365	Human	PMID:8670882
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:P53365	Human	PMID:9312003
Molecular Function	GO:0005515	protein binding	RAC1	IPI	UniProtKB:Q54K32	Human	PMID:9739079
Molecular Function	GO:0005515	protein binding	Rac1	IPI	UniProtKB:Q13153	Mouse	MGI:MGI:4429755|PMID:19893577
Molecular Function	GO:0005515	protein binding	Rac1	IPI	UniProtKB:Q13153	Mouse	MGI:MGI:5447607|PMID:18325335
Molecular Function	GO:0005515	protein binding	Rac1	IPI	UniProtKB:Q62108	Mouse	MGI:MGI:6092779|PMID:28671696
Molecular Function	GO:0005515	protein binding	Rac1	IPI	UniProtKB:Q8BWW9	Mouse	MGI:MGI:4941685|PMID:20974804
Molecular Function	GO:0005515	protein binding	Rac1	IPI	UniProtKB:Q5SSM3	Mouse	MGI:MGI:5582709|PMID:24352656
Molecular Function	GO:0005515	protein binding	Rac1	IPI	UniProtKB:Q62108	Mouse	MGI:MGI:4359331|PMID:19455133
Molecular Function	GO:0005515	protein binding	Rac1	IPI	UniProtKB:Q13153	Mouse	MGI:MGI:3828223|PMID:18854161
Molecular Function	GO:0005515	protein binding	Rac1	IPI	UniProtKB:Q8BK67	Mouse	MGI:MGI:5621257|PMID:25074804
Molecular Function	GO:0005515	protein binding	Rac1	IPI	UniProtKB:Q9WUM4	Mouse	MGI:MGI:5621257|PMID:25074804
Molecular Function	GO:0005515	protein binding	Rac1	IPI	UniProtKB:Q69ZI1	Mouse	MGI:MGI:6158752|PMID:22959435
Molecular Function	GO:0005515	protein binding	Rac1	IPI	UniProtKB:P08228	Mouse	MGI:MGI:3774718|PMID:18219391
Molecular Function	GO:0005515	protein binding	Rac1	IPI	PR:Q9JJR5	Mouse	PMID:17227220
Molecular Function	GO:0005515	protein binding	Rac1	IPI	MGI:MGI:3028642	Mouse	PMID:18604197
Molecular Function	GO:0005515	protein binding	Rac1	IPI	PR:Q07139	Mouse	PMID:8464478
Molecular Function	GO:0005515	protein binding	Rac1	IPI	PR:Q9JKF1	Mouse	PMID:18604197
Molecular Function	GO:0005515	protein binding	Rac1	IPI	PR:Q9CR75	Mouse	PMID:14573547
Molecular Function	GO:0005515	protein binding	Rac1	IPI	RGD:620632	Rat	PMID:15608632|RGD:1581694
Molecular Function	GO:0005515	protein binding	Rac1	IPI	UniProtKB:P52631	Rat	PMID:16055727|RGD:13792550
Molecular Function	GO:0005515	protein binding	Rac1	IPI	RGD:1354371	Rat	PMID:20472934|RGD:7242691
Molecular Function	GO:0005515	protein binding	Rac1	IPI	UniProtKB:Q5XI73	Rat	PMID:20696765|RGD:8554409
Molecular Function	GO:0005515	protein binding	Rac1	IPI	UniProtKB:Q9QY40	Rat	PMID:20696765|RGD:8554409
Molecular Function	GO:0005515	protein binding	Rac1	IPI	UniProtKB:Q498M5	Rat	PMID:22128169|RGD:13673844
Molecular Function	GO:0019901	protein kinase binding	RAC1	IPI	UniProtKB:Q13177	Human	PMID:8625410
Molecular Function	GO:0019901	protein kinase binding	Rac1	IPI	UniProtKB:D3ZG85	Rat	PMID:20861382|RGD:8554575
Molecular Function	GO:0044877	protein-containing complex binding	RAC1	IDA		Human	PMID:21107423
Molecular Function	GO:0051022	Rho GDP-dissociation inhibitor binding	Rac1	IPI	RGD:1359547	Rat	PMID:22564631|RGD:9684983
Molecular Function	GO:0031267	small GTPase binding	Rac1	IPI	RGD:61908	Rat	PMID:16040606|RGD:4892340
Molecular Function	GO:0031996	thioesterase binding	RAC1	IPI	UniProtKB:P35125	Human	PMID:12612085
Cellular Component	GO:0005884	actin filament	RAC1	IDA		Human	PMID:19625648
Cellular Component	GO:0005938	cell cortex	RAC1	IDA		Human	PMID:19126672
Cellular Component	GO:0042995	cell projection	Rac1	IDA		Mouse	PMID:15728722
Cellular Component	GO:0005737	cytoplasm	RAC1	IDA		Human	PMID:19625648
Cellular Component	GO:0005737	cytoplasm	Rac1	IDA		Mouse	MGI:MGI:5621257|PMID:25074804
Cellular Component	GO:0005737	cytoplasm	Rac1	IDA		Mouse	PMID:12213441
Cellular Component	GO:0005737	cytoplasm	Rac1	IDA		Rat	PMID:16040606|RGD:4892340
Cellular Component	GO:0036464	cytoplasmic ribonucleoprotein granule	RAC1	IDA		Human	PMID:15121898
Cellular Component	GO:0031410	cytoplasmic vesicle	Rac1	IDA		Mouse	PMID:14516655
Cellular Component	GO:0031410	cytoplasmic vesicle	Rac1	IDA		Mouse	PMID:12783890
Cellular Component	GO:0031410	cytoplasmic vesicle	Rac1	IDA		Rat	PMID:16040606|RGD:4892340
Cellular Component	GO:0005829	cytosol	Rac1	IDA		Rat	PMID:20696765|RGD:8554409
Cellular Component	GO:0043197	dendritic spine	RAC1	IDA		Human	PMID:24352656
Cellular Component	GO:0043197	dendritic spine	Rac1	IDA		Rat	PMID:15800193|RGD:12050102
Cellular Component	GO:0031901	early endosome membrane	Rac1	IDA		Mouse	MGI:MGI:5621257|PMID:25074804
Cellular Component	GO:0070062	extracellular exosome	RAC1	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	RAC1	HDA		Human	PMID:23533145
Cellular Component	GO:0005925	focal adhesion	RAC1	HDA		Human	PMID:21423176
Cellular Component	GO:0098982	GABA-ergic synapse	Rac1	EXP		Rat	PMID:25284783|RGD:13702191
Cellular Component	GO:0098982	GABA-ergic synapse	Rac1	IDA		Rat	PMID:25284783|RGD:13702191
Cellular Component	GO:0098982	GABA-ergic synapse	Rac1	IMP		Rat	PMID:25284783|RGD:13702191
Cellular Component	GO:0098978	glutamatergic synapse	RAC1	IDA		Human	PMID:15800193
Cellular Component	GO:0098978	glutamatergic synapse	RAC1	IMP		Human	PMID:15800193
Cellular Component	GO:0098978	glutamatergic synapse	RAC1	IDA		Human	PMID:24352656
Cellular Component	GO:0098978	glutamatergic synapse	RAC1	IMP		Human	PMID:24352656
Cellular Component	GO:0000139	Golgi membrane	Rac1	IDA		Rat	PMID:15147909|RGD:2306211
Cellular Component	GO:0060091	kinocilium	Rac1	IDA		Mouse	PMID:23533177
Cellular Component	GO:0030027	lamellipodium	RAC1	IDA		Human	PMID:19625648
Cellular Component	GO:0030027	lamellipodium	RAC1	IDA		Human	PMID:19126672
Cellular Component	GO:0030027	lamellipodium	Rac1	IDA		Mouse	MGI:MGI:6158752|PMID:22959435
Cellular Component	GO:0030027	lamellipodium	Rac1	IDA		Mouse	PMID:12783890
Cellular Component	GO:0030027	lamellipodium	Rac1	IDA		Mouse	PMID:14657280
Cellular Component	GO:0016020	membrane	Rac1	IDA		Mouse	PMID:14657280
Cellular Component	GO:0016020	membrane	Rac1	IDA		Rat	PMID:20696765|RGD:8554409
Cellular Component	GO:0005634	nucleus	RAC1	IDA		Human	PMID:12551911
Cellular Component	GO:0005634	nucleus	Rac1	IDA		Mouse	MGI:MGI:5621257|PMID:25074804
Cellular Component	GO:0000242	pericentriolar material	Rac1	IDA		Mouse	PMID:23533177
Cellular Component	GO:0001891	phagocytic cup	Rac1	IDA		Mouse	MGI:MGI:5315376|PMID:10934045
Cellular Component	GO:0005886	plasma membrane	RAC1	IDA		Human	PMID:10036235
Cellular Component	GO:0005886	plasma membrane	Rac1	IDA		Mouse	MGI:MGI:5621257|PMID:25074804
Cellular Component	GO:0005886	plasma membrane	Rac1	IDA		Mouse	PMID:14516655
Cellular Component	GO:0098794	postsynapse	RAC1	IDA		Human	PMID:15800193
Cellular Component	GO:0098794	postsynapse	RAC1	IMP		Human	PMID:15800193
Cellular Component	GO:0098794	postsynapse	RAC1	IDA		Human	PMID:24352656
Cellular Component	GO:0098794	postsynapse	RAC1	IMP		Human	PMID:24352656
Cellular Component	GO:0055038	recycling endosome membrane	RAC1	IDA		Human	PMID:10036235
Cellular Component	GO:0032587	ruffle membrane	RAC1	IDA		Human	PMID:20875796
Cellular Component	GO:0032587	ruffle membrane	Rac1	IDA		Mouse	MGI:MGI:5315376|PMID:10934045
Cellular Component	GO:0005802	trans-Golgi network	RAC1	IDA		Human	PMID:12915445
Biological Process	GO:0030036	actin cytoskeleton organization	RAC1	IGI	UniProtKB:P17105	Human	PMID:19890013
Biological Process	GO:0030036	actin cytoskeleton organization	Rac1	IDA		Rat	PMID:10350213|RGD:1599401
Biological Process	GO:0007015	actin filament organization	Rac1	IMP		Rat	PMID:12413953|RGD:4145648
Biological Process	GO:0030041	actin filament polymerization	Rac1	IDA		Mouse	PMID:22750946
Biological Process	GO:0048532	anatomical structure arrangement	Rac1	IMP	MGI:MGI:2663662	Mouse	PMID:20016102
Biological Process	GO:0048532	anatomical structure arrangement	Rac1	IMP	MGI:MGI:2663669	Mouse	PMID:20016102
Biological Process	GO:0086098	angiotensin-activated signaling pathway involved in heart process	Rac1	IDA		Mouse	PMID:26975711
Biological Process	GO:0002093	auditory receptor cell morphogenesis	Rac1	IMP	MGI:MGI:2663669	Mouse	PMID:20016102
Biological Process	GO:0002093	auditory receptor cell morphogenesis	Rac1	IMP	MGI:MGI:2663662	Mouse	PMID:20016102
Biological Process	GO:0007411	axon guidance	Rac1	IMP	MGI:MGI:1932522,MGI:MGI:2663662	Mouse	PMID:17409253
Biological Process	GO:0045453	bone resorption	Rac1	IDA		Rat	PMID:10350213|RGD:1599401
Biological Process	GO:0007155	cell adhesion	Rac1	IDA		Mouse	PMID:14657280
Biological Process	GO:0016477	cell migration	RAC1	IMP		Human	PMID:26934001
Biological Process	GO:0016477	cell migration	Rac1	IDA		Mouse	PMID:15728191
Biological Process	GO:0042074	cell migration involved in gastrulation	rac1a	IGI	ZFIN:ZDB-MRPHLNO-121031-9	Zfish	PMID:22911626
Biological Process	GO:0048870	cell motility	RAC1	IDA		Human	PMID:19403692
Biological Process	GO:0008283	cell population proliferation	Rac1	IMP		Rat	PMID:11756405|RGD:1299245
Biological Process	GO:0045216	cell-cell junction organization	Rac1	IMP	MGI:MGI:2663669	Mouse	PMID:20016102
Biological Process	GO:0045216	cell-cell junction organization	Rac1	IMP	MGI:MGI:2663662	Mouse	PMID:20016102
Biological Process	GO:0071260	cellular response to mechanical stimulus	Rac1	IDA		Rat	PMID:12105187|RGD:1299247
Biological Process	GO:0021894	cerebral cortex GABAergic interneuron development	Rac1	IGI	MGI:MGI:2180784	Mouse	PMID:23258346
Biological Process	GO:0021799	cerebral cortex radially oriented cell migration	Rac1	IMP	MGI:MGI:1932522,MGI:MGI:2663662	Mouse	PMID:17409253
Biological Process	GO:0006935	chemotaxis	Rac1	IMP		Rat	PMID:11756405|RGD:1299245
Biological Process	GO:0090103	cochlea morphogenesis	Rac1	IMP	MGI:MGI:2663662	Mouse	PMID:20016102
Biological Process	GO:0090103	cochlea morphogenesis	Rac1	IMP	MGI:MGI:2663669	Mouse	PMID:20016102
Biological Process	GO:0007010	cytoskeleton organization	Rac1	IDA		Mouse	PMID:14657280
Biological Process	GO:0016358	dendrite development	Rac1	IDA		Mouse	PMID:12213441
Biological Process	GO:0048813	dendrite morphogenesis	Rac1	IGI	MGI:MGI:1891740	Mouse	PMID:20335472
Biological Process	GO:0071542	dopaminergic neuron differentiation	Rac1	IGI	MGI:MGI:98958	Mouse	PMID:18953410
Biological Process	GO:0021831	embryonic olfactory bulb interneuron precursor migration	Rac1	IMP	MGI:MGI:1932522,MGI:MGI:2663662	Mouse	PMID:17409253
Biological Process	GO:0006897	endocytosis	Rac1	IDA		Mouse	PMID:12446704
Biological Process	GO:0043652	engulfment of apoptotic cell	Rac1	IDA		Mouse	MGI:MGI:4943793|PMID:20691665
Biological Process	GO:0003382	epithelial cell morphogenesis	Rac1	IMP	MGI:MGI:2663662	Mouse	PMID:20016102
Biological Process	GO:0003382	epithelial cell morphogenesis	Rac1	IMP	MGI:MGI:2663669	Mouse	PMID:20016102
Biological Process	GO:0030900	forebrain development	Rac1	IDA		Mouse	MGI:MGI:3827084|PMID:19007770
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	Rac1	IGI	MGI:MGI:98923	Mouse	PMID:21178006
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	Rac1	IGI	MGI:MGI:3040696	Mouse	PMID:21178006
Biological Process	GO:0048012	hepatocyte growth factor receptor signaling pathway	RAC1	IMP		Human	PMID:25198505
Biological Process	GO:0048873	homeostasis of number of cells within a tissue	Rac1	IGI	MGI:MGI:2180784	Mouse	PMID:23258346
Biological Process	GO:0006972	hyperosmotic response	Rac1	IDA		Mouse	PMID:12783890
Biological Process	GO:1904936	interneuron migration	Rac1	IMP	MGI:MGI:1932522,MGI:MGI:2663662	Mouse	PMID:17409253
Biological Process	GO:0030032	lamellipodium assembly	RAC1	IMP		Human	PMID:9312003
Biological Process	GO:0030032	lamellipodium assembly	Rac1	IDA		Mouse	PMID:15728191
Biological Process	GO:0051179	localization	RAC1	IDA		Human	PMID:12874273
Biological Process	GO:0051668	localization within membrane	RAC1	IMP		Human	PMID:16636067
Biological Process	GO:0002551	mast cell chemotaxis	Rac1	IMP		Rat	PMID:12413953|RGD:4145648
Biological Process	GO:1904948	midbrain dopaminergic neuron differentiation	Rac1	IMP		Mouse	MGI:MGI:3829860|PMID:18953410
Biological Process	GO:1904948	midbrain dopaminergic neuron differentiation	Rac1	IMP		Mouse	MGI:MGI:5466648|PMID:23109420
Biological Process	GO:0007520	myoblast fusion	rac1a	IMP	ZFIN:ZDB-MRPHLNO-070831-3	Zfish	PMID:17529975
Biological Process	GO:0007520	myoblast fusion	rac1a	IDA		Zfish	PMID:17529975
Biological Process	GO:0010764	negative regulation of fibroblast migration	RAC1	IDA		Human	PMID:19126672
Biological Process	GO:0032707	negative regulation of interleukin-23 production	RAC1	IDA		Human	PMID:16982892
Biological Process	GO:0001764	neuron migration	Rac1	IMP		Mouse	MGI:MGI:6158752|PMID:22959435
Biological Process	GO:0001764	neuron migration	Rac1	IMP	MGI:MGI:1932522,MGI:MGI:2663662	Mouse	PMID:17409253
Biological Process	GO:0048812	neuron projection morphogenesis	Rac1	IGI	UniProtKB:P22725	Mouse	MGI:MGI:4949958|PMID:21483795
Biological Process	GO:0030593	neutrophil chemotaxis	rac1a	IGI	ZFIN:ZDB-GENE-040625-27	Zfish	PMID:27837107
Biological Process	GO:0035567	non-canonical Wnt signaling pathway	Rac1	IGI	UniProtKB:P22725	Mouse	MGI:MGI:4949958|PMID:21483795
Biological Process	GO:0006911	phagocytosis, engulfment	Rac1	IMP		Mouse	MGI:MGI:5315376|PMID:10934045
Biological Process	GO:0030838	positive regulation of actin filament polymerization	Rac1	IDA		Mouse	PMID:12853475
Biological Process	GO:0010811	positive regulation of cell-substrate adhesion	RAC1	IGI	UniProtKB:P48059	Human	PMID:20926685
Biological Process	GO:0010811	positive regulation of cell-substrate adhesion	RAC1	IGI	UniProtKB:Q15404	Human	PMID:20926685
Biological Process	GO:0060999	positive regulation of dendritic spine development	Rac1	IGI	MGI:MGI:2685385	Mouse	PMID:25865668
Biological Process	GO:0060999	positive regulation of dendritic spine development	Rac1	IMP		Mouse	PMID:25865668
Biological Process	GO:0045740	positive regulation of DNA replication	Rac1	IMP		Rat	PMID:9487126|RGD:2293350
Biological Process	GO:0010595	positive regulation of endothelial cell migration	RAC1	IMP		Human	PMID:18558630
Biological Process	GO:0051491	positive regulation of filopodium assembly	Rac1	IMP		Rat	PMID:15788770|RGD:2314386
Biological Process	GO:0051894	positive regulation of focal adhesion assembly	RAC1	IDA		Human	PMID:23129259
Biological Process	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus	Rac1	IMP		Mouse	MGI:MGI:5489045|PMID:23412604
Biological Process	GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus	Rac1	IMP		Rat	PMID:23412604|RGD:14392803
Biological Process	GO:0010592	positive regulation of lamellipodium assembly	RAC1	IDA		Human	PMID:15467718
Biological Process	GO:0010592	positive regulation of lamellipodium assembly	RAC1	IMP		Human	PMID:19625648
Biological Process	GO:0010592	positive regulation of lamellipodium assembly	RAC1	IMP		Human	PMID:8625410
Biological Process	GO:0010592	positive regulation of lamellipodium assembly	Rac1	IMP		Rat	PMID:12105187|RGD:1299247
Biological Process	GO:0031116	positive regulation of microtubule polymerization	RAC1	IMP		Human	PMID:25198505
Biological Process	GO:0090023	positive regulation of neutrophil chemotaxis	RAC1	IMP		Human	PMID:19625648
Biological Process	GO:0090023	positive regulation of neutrophil chemotaxis	Rac1	IMP		Mouse	MGI:MGI:4355276|PMID:19625648
Biological Process	GO:2000386	positive regulation of ovarian follicle development	Rac1	IMP		Mouse	MGI:MGI:6217799|PMID:27050391
Biological Process	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	Rac1	IMP		Mouse	PMID:15728722
Biological Process	GO:0001934	positive regulation of protein phosphorylation	RAC1	IMP		Human	PMID:23633677
Biological Process	GO:0051496	positive regulation of stress fiber assembly	RAC1	IDA		Human	PMID:23129259
Biological Process	GO:0051496	positive regulation of stress fiber assembly	RAC1	IMP		Human	PMID:8625410
Biological Process	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading	RAC1	IDA		Human	PMID:23129259
Biological Process	GO:0098974	postsynaptic actin cytoskeleton organization	Rac1	EXP		Rat	PMID:25284783|RGD:13702191
Biological Process	GO:0098974	postsynaptic actin cytoskeleton organization	Rac1	IDA		Rat	PMID:25284783|RGD:13702191
Biological Process	GO:0098974	postsynaptic actin cytoskeleton organization	Rac1	IMP		Rat	PMID:25284783|RGD:13702191
Biological Process	GO:0072659	protein localization to plasma membrane	Rac1	IDA		Mouse	PMID:23184663
Biological Process	GO:0016601	Rac protein signal transduction	Rac1	IDA		Rat	PMID:15800193|RGD:12050102
Biological Process	GO:0061344	regulation of cell adhesion involved in heart morphogenesis	Rac1	IMP		Mouse	MGI:MGI:5634261|PMID:25514037
Biological Process	GO:0030334	regulation of cell migration	RAC1	IMP		Human	PMID:19934221
Biological Process	GO:0030334	regulation of cell migration	RAC1	IMP		Human	PMID:22036506
Biological Process	GO:0022604	regulation of cell morphogenesis	Rac1	IGI	MGI:MGI:2180784	Mouse	PMID:23258346
Biological Process	GO:0008361	regulation of cell size	RAC1	IGI	UniProtKB:P35241	Human	PMID:22467863
Biological Process	GO:0008361	regulation of cell size	RAC1	IMP		Human	PMID:22467863
Biological Process	GO:0070376	regulation of ERK5 cascade	Rac1	IDA		Mouse	PMID:26975711
Biological Process	GO:0010762	regulation of fibroblast migration	Rac1	IMP		Mouse	MGI:MGI:5621257|PMID:25074804
Biological Process	GO:0010591	regulation of lamellipodium assembly	RAC1	IGI	UniProtKB:P42768	Human	PMID:8625410
Biological Process	GO:0014041	regulation of neuron maturation	Rac1	IGI	MGI:MGI:2180784	Mouse	PMID:23258346
Biological Process	GO:2001222	regulation of neuron migration	Rac1	IMP	MGI:MGI:1932522,MGI:MGI:2663662	Mouse	PMID:17409253
Biological Process	GO:0048168	regulation of neuronal synaptic plasticity	Rac1	IGI	MGI:MGI:2685385	Mouse	PMID:25865668
Biological Process	GO:0048168	regulation of neuronal synaptic plasticity	Rac1	IMP		Mouse	PMID:25865668
Biological Process	GO:0045428	regulation of nitric oxide biosynthetic process	Rac1	IGI	UniProtKB:P97710	Rat	PMID:16055727|RGD:13792550
Biological Process	GO:0046425	regulation of receptor signaling pathway via JAK-STAT	Rac1	IMP		Mouse	MGI:MGI:6217799|PMID:27050391
Biological Process	GO:0060263	regulation of respiratory burst	RAC1	IDA		Human	PMID:16636067
Biological Process	GO:0051492	regulation of stress fiber assembly	RAC1	IGI	UniProtKB:P42768	Human	PMID:8625410
Biological Process	GO:0097178	ruffle assembly	RAC1	IMP		Human	PMID:10036235
Biological Process	GO:0097178	ruffle assembly	Rac1	IMP		Mouse	MGI:MGI:5315376|PMID:10934045
Biological Process	GO:0031529	ruffle organization	RAC1	IDA		Human	PMID:15467718
Biological Process	GO:0071526	semaphorin-plexin signaling pathway	Rac1	IMP		Rat	PMID:20696765|RGD:8554409
Biological Process	GO:0007264	small GTPase mediated signal transduction	RAC1	IMP		Human	PMID:26934001
Biological Process	GO:0007264	small GTPase mediated signal transduction	Rac1	IDA		Mouse	PMID:12525493
Biological Process	GO:0007264	small GTPase mediated signal transduction	Rac1	IDA		Mouse	PMID:23967341
Biological Process	GO:0003376	sphingosine-1-phosphate receptor signaling pathway	RAC1	IMP		Human	PMID:18558630
Biological Process	GO:0034446	substrate adhesion-dependent cell spreading	RAC1	IMP		Human	PMID:19625648
Biological Process	GO:0034446	substrate adhesion-dependent cell spreading	RAC1	IMP		Human	PMID:28886345
Biological Process	GO:0034446	substrate adhesion-dependent cell spreading	Rac1	IMP		Mouse	MGI:MGI:4355276|PMID:19625648
Biological Process	GO:0034446	substrate adhesion-dependent cell spreading	Rac1	IDA		Mouse	PMID:18156211
Biological Process	GO:0051932	synaptic transmission, GABAergic	Rac1	IGI	MGI:MGI:2180784	Mouse	PMID:23258346
Biological Process	GO:0060071	Wnt signaling pathway, planar cell polarity pathway	Rac1	IGI	MGI:MGI:98958	Mouse	PMID:18953410

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern