Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RACGAP1
  • Mouse genes Racgap1
  • Rat genes Racgap1
  • Zfish genes racgap1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Racgap1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0043014	alpha-tubulin binding	RACGAP1	IDA		Human	PMID:11085985
Molecular Function	GO:0048487	beta-tubulin binding	RACGAP1	IDA		Human	PMID:11085985
Molecular Function	GO:0043015	gamma-tubulin binding	RACGAP1	IDA		Human	PMID:11085985
Molecular Function	GO:0005096	GTPase activator activity	RACGAP1	IDA		Human	PMID:10979956
Molecular Function	GO:0005096	GTPase activator activity	RACGAP1	IMP		Human	PMID:15642749
Molecular Function	GO:0008017	microtubule binding	RACGAP1	IDA		Human	PMID:11782313
Molecular Function	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	RACGAP1	IDA		Human	PMID:23235882
Molecular Function	GO:0005515	protein binding	RACGAP1	IPI	UniProtKB:Q96RN1	Human	PMID:11278976
Molecular Function	GO:0005515	protein binding	RACGAP1	IPI	UniProtKB:Q02241	Human	PMID:11782313
Molecular Function	GO:0005515	protein binding	RACGAP1	IPI	UniProtKB:P52198	Human	PMID:12590651
Molecular Function	GO:0005515	protein binding	RACGAP1	IPI	UniProtKB:Q96GD4	Human	PMID:12689593
Molecular Function	GO:0005515	protein binding	RACGAP1	IPI	UniProtKB:O43663	Human	PMID:14744859
Molecular Function	GO:0005515	protein binding	RACGAP1	IPI	UniProtKB:Q9H8V3	Human	PMID:16103226
Molecular Function	GO:0005515	protein binding	RACGAP1	IPI	UniProtKB:Q9H8V3	Human	PMID:16129829
Molecular Function	GO:0005515	protein binding	RACGAP1	IPI	UniProtKB:Q02241	Human	PMID:16236794
Molecular Function	GO:0005515	protein binding	RACGAP1	IPI	UniProtKB:Q9H8V3	Human	PMID:16236794
Molecular Function	GO:0005515	protein binding	RACGAP1	IPI	UniProtKB:Q02241	Human	PMID:18201571
Molecular Function	GO:0005515	protein binding	RACGAP1	IPI	UniProtKB:Q16537	Human	PMID:18201571
Molecular Function	GO:0005515	protein binding	RACGAP1	IPI	UniProtKB:Q9H8V3	Human	PMID:18201571
Molecular Function	GO:0005515	protein binding	RACGAP1	IPI	UniProtKB:O75154	Human	PMID:18511905
Molecular Function	GO:0005515	protein binding	RACGAP1	IPI	UniProtKB:Q9H8V3	Human	PMID:18511905
Molecular Function	GO:0005515	protein binding	RACGAP1	IPI	UniProtKB:P53350	Human	PMID:19468300
Molecular Function	GO:0005515	protein binding	RACGAP1	IPI	UniProtKB:Q9H8V3	Human	PMID:19468300
Molecular Function	GO:0005515	protein binding	RACGAP1	IPI	UniProtKB:P53350	Human	PMID:19468302
Molecular Function	GO:0005515	protein binding	RACGAP1	IPI	UniProtKB:Q9H8V3	Human	PMID:19468302
Molecular Function	GO:0005515	protein binding	RACGAP1	IPI	UniProtKB:Q02241	Human	PMID:22580824
Molecular Function	GO:0005515	protein binding	RACGAP1	IPI	UniProtKB:P35221	Human	PMID:22750944
Molecular Function	GO:0005515	protein binding	RACGAP1	IPI	UniProtKB:Q9H8V3	Human	PMID:22750944
Molecular Function	GO:0005515	protein binding	RACGAP1	IPI	UniProtKB:Q9H8V3	Human	PMID:25068414
Molecular Function	GO:0005515	protein binding	RACGAP1	IPI	UniProtKB:Q9P258	Human	PMID:25074804
Molecular Function	GO:0005515	protein binding	RACGAP1	IPI	UniProtKB:Q9UBU8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RACGAP1	IPI	UniProtKB:Q02241	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	RACGAP1	IPI	UniProtKB:Q00526	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RACGAP1	IPI	UniProtKB:Q13895	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RACGAP1	IPI	UniProtKB:Q9Y228	Human	PMID:32296183
Molecular Function	GO:0019901	protein kinase binding	RACGAP1	IPI	UniProtKB:P53350	Human	PMID:19468302
Cellular Component	GO:0097149	centralspindlin complex	RACGAP1	IDA		Human	PMID:11782313
Cellular Component	GO:0097149	centralspindlin complex	RACGAP1	IDA		Human	PMID:16236794
Cellular Component	GO:0032154	cleavage furrow	RACGAP1	IDA		Human	PMID:16103226
Cellular Component	GO:0070062	extracellular exosome	RACGAP1	HDA		Human	PMID:19199708
Cellular Component	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane	RACGAP1	IDA		Human	PMID:23235882
Cellular Component	GO:0030496	midbody	RACGAP1	IDA		Human	PMID:11782313
Cellular Component	GO:0030496	midbody	RACGAP1	IDA		Human	PMID:16103226
Cellular Component	GO:0030496	midbody	RACGAP1	IDA		Human	PMID:18511905
Cellular Component	GO:0072686	mitotic spindle	RACGAP1	IMP		Human	PMID:15642749
Cellular Component	GO:0072686	mitotic spindle	RACGAP1	IDA		Human	PMID:16103226
Cellular Component	GO:0005654	nucleoplasm	RACGAP1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	RACGAP1	IDA		Human	GO_REF:0000054
Cellular Component	GO:0005634	nucleus	RACGAP1	IDA		Human	PMID:11085985
Cellular Component	GO:0005634	nucleus	RACGAP1	IDA		Human	PMID:11782313
Cellular Component	GO:0005634	nucleus	RACGAP1	IDA		Human	PMID:16103226
Cellular Component	GO:0005634	nucleus	RACGAP1	IDA		Human	PMID:18445686
Cellular Component	GO:0005819	spindle	RACGAP1	IDA		Human	PMID:18445686
Cellular Component	GO:0051233	spindle midzone	RACGAP1	IDA		Human	PMID:19468302
Biological Process	GO:0000915	actomyosin contractile ring assembly	RACGAP1	IMP		Human	PMID:16129829
Biological Process	GO:0030218	erythrocyte differentiation	RACGAP1	IMP		Human	PMID:34818416
Biological Process	GO:0007507	heart development	racgap1	IMP	ZFIN:ZDB-CRISPR-201116-6	Zfish	PMID:32368696
Biological Process	GO:0000226	microtubule cytoskeleton organization	racgap1	IMP	ZFIN:ZDB-GENO-980202-988	Zfish	PMID:27339293
Biological Process	GO:0000281	mitotic cytokinesis	RACGAP1	IDA		Human	PMID:11085985
Biological Process	GO:0000281	mitotic cytokinesis	RACGAP1	IMP		Human	PMID:16236794
Biological Process	GO:0000281	mitotic cytokinesis	RACGAP1	IDA		Human	PMID:19468302
Biological Process	GO:0000281	mitotic cytokinesis	RACGAP1	IMP		Human	PMID:23235882
Biological Process	GO:0000281	mitotic cytokinesis	racgap1	IMP	ZFIN:ZDB-GENO-980202-988	Zfish	PMID:27339293
Biological Process	GO:0051256	mitotic spindle midzone assembly	RACGAP1	IDA		Human	PMID:16103226
Biological Process	GO:0007405	neuroblast proliferation	Racgap1	IEP		Mouse	MGI:MGI:1346363|PMID:10493933
Biological Process	GO:0032467	positive regulation of cytokinesis	RACGAP1	IMP		Human	PMID:11782313
Biological Process	GO:0032467	positive regulation of cytokinesis	RACGAP1	IMP		Human	PMID:15642749
Biological Process	GO:0032467	positive regulation of cytokinesis	RACGAP1	IDA		Human	PMID:16103226
Biological Process	GO:0051988	regulation of attachment of spindle microtubules to kinetochore	RACGAP1	IMP		Human	PMID:15642749
Biological Process	GO:0045995	regulation of embryonic development	Racgap1	IMP		Mouse	MGI:MGI:1934490|PMID:11287179
Biological Process	GO:0007283	spermatogenesis	RACGAP1	IEP		Human	PMID:12590651
Biological Process	GO:0008272	sulfate transport	RACGAP1	IDA		Human	PMID:11278976

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern