Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RAD21
  • Mouse genes Rad21
  • Rat genes Rad21
  • Zfish genes rad21a,rad21b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rad21

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	RAD21	IPI	UniProtKB:Q14674	Human	PMID:12672959
Molecular Function	GO:0005515	protein binding	RAD21	IPI	UniProtKB:Q8WVB6	Human	PMID:12930902
Molecular Function	GO:0005515	protein binding	RAD21	IPI	UniProtKB:Q9CPY3	Human	PMID:15837422
Molecular Function	GO:0005515	protein binding	RAD21	IPI	UniProtKB:Q29RF7	Human	PMID:15855230
Molecular Function	GO:0005515	protein binding	RAD21	IPI	UniProtKB:Q9NTI5	Human	PMID:15855230
Molecular Function	GO:0005515	protein binding	RAD21	IPI	UniProtKB:Q9UQE7	Human	PMID:15855230
Molecular Function	GO:0005515	protein binding	RAD21	IPI	UniProtKB:Q9UQE7	Human	PMID:16802858
Molecular Function	GO:0005515	protein binding	RAD21	IPI	UniProtKB:Q96FC9	Human	PMID:17105772
Molecular Function	GO:0005515	protein binding	RAD21	IPI	UniProtKB:Q14683	Human	PMID:17112726
Molecular Function	GO:0005515	protein binding	RAD21	IPI	UniProtKB:Q29RF7	Human	PMID:17112726
Molecular Function	GO:0005515	protein binding	RAD21	IPI	UniProtKB:Q7Z5K2	Human	PMID:17112726
Molecular Function	GO:0005515	protein binding	RAD21	IPI	UniProtKB:Q9NTI5	Human	PMID:17112726
Molecular Function	GO:0005515	protein binding	RAD21	IPI	UniProtKB:Q9UQE7	Human	PMID:17112726
Molecular Function	GO:0005515	protein binding	RAD21	IPI	UniProtKB:Q14683	Human	PMID:17113138
Molecular Function	GO:0005515	protein binding	RAD21	IPI	UniProtKB:Q29RF7	Human	PMID:17113138
Molecular Function	GO:0005515	protein binding	RAD21	IPI	UniProtKB:Q7Z5K2	Human	PMID:17113138
Molecular Function	GO:0005515	protein binding	RAD21	IPI	UniProtKB:Q8N3U4	Human	PMID:17113138
Molecular Function	GO:0005515	protein binding	RAD21	IPI	UniProtKB:Q9NTI5	Human	PMID:17113138
Molecular Function	GO:0005515	protein binding	RAD21	IPI	UniProtKB:Q9UQE7	Human	PMID:17113138
Molecular Function	GO:0005515	protein binding	RAD21	IPI	UniProtKB:Q9UQE7	Human	PMID:17349791
Molecular Function	GO:0005515	protein binding	RAD21	IPI	UniProtKB:Q8N3U4	Human	PMID:17962804
Molecular Function	GO:0005515	protein binding	RAD21	IPI	UniProtKB:Q9UQE7	Human	PMID:18235444
Molecular Function	GO:0005515	protein binding	RAD21	IPI	UniProtKB:Q8N3U4	Human	PMID:19629043
Molecular Function	GO:0005515	protein binding	RAD21	IPI	UniProtKB:Q7Z5K2	Human	PMID:19696148
Molecular Function	GO:0005515	protein binding	RAD21	IPI	UniProtKB:Q7Z5K2	Human	PMID:20360068
Molecular Function	GO:0005515	protein binding	RAD21	IPI	UniProtKB:Q14683	Human	PMID:20818333
Molecular Function	GO:0005515	protein binding	RAD21	IPI	UniProtKB:Q8N3U4	Human	PMID:20818333
Molecular Function	GO:0005515	protein binding	RAD21	IPI	UniProtKB:Q9NP77	Human	PMID:20818333
Molecular Function	GO:0005515	protein binding	RAD21	IPI	UniProtKB:Q9UQE7	Human	PMID:20818333
Molecular Function	GO:0005515	protein binding	RAD21	IPI	UniProtKB:Q9NTI5	Human	PMID:22293751
Molecular Function	GO:0005515	protein binding	RAD21	IPI	UniProtKB:Q14683	Human	PMID:22885700
Molecular Function	GO:0005515	protein binding	RAD21	IPI	UniProtKB:Q8N3U4	Human	PMID:22885700
Molecular Function	GO:0005515	protein binding	RAD21	IPI	UniProtKB:Q9UQE7	Human	PMID:22885700
Molecular Function	GO:0005515	protein binding	RAD21	IPI	UniProtKB:Q14683	Human	PMID:23242214
Molecular Function	GO:0005515	protein binding	RAD21	IPI	UniProtKB:Q8N3U4	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	RAD21	IPI	UniProtKB:Q7Z5K2	Human	PMID:25173175
Molecular Function	GO:0005515	protein binding	RAD21	IPI	UniProtKB:Q8N3U4	Human	PMID:25173175
Molecular Function	GO:0005515	protein binding	RAD21	IPI	UniProtKB:Q13643	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RAD21	IPI	UniProtKB:Q14683	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	RAD21	IPI	UniProtKB:Q29RF7	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	RAD21	IPI	UniProtKB:Q7Z5K2	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	RAD21	IPI	UniProtKB:Q8N3U4	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	RAD21	IPI	UniProtKB:Q9UQE7	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	RAD21	IPI	UniProtKB:Q14683	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	RAD21	IPI	UniProtKB:Q29RF7	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	RAD21	IPI	UniProtKB:Q9UQE7	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	RAD21	IPI	UniProtKB:Q8N3U4	Human	PMID:29263825
Molecular Function	GO:0005515	protein binding	RAD21	IPI	UniProtKB:Q8N3U4	Human	PMID:29867216
Molecular Function	GO:0005515	protein binding	RAD21	IPI	UniProtKB:Q13643	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	Rad21	IPI	UniProtKB:Q9CU62,UniProtKB:Q9CW03	Mouse	MGI:MGI:1340883|PMID:10375619
Molecular Function	GO:0005515	protein binding	Rad21	IPI	PR:Q924K8	Mouse	PMID:22075476
Molecular Function	GO:0043565	sequence-specific DNA binding	rad21a	IDA		Zfish	PMID:20553708
Cellular Component	GO:0000785	chromatin	Rad21	IDA		Mouse	PMID:23920377
Cellular Component	GO:0000775	chromosome, centromeric region	Rad21	IDA		Mouse	PMID:26919979
Cellular Component	GO:0008278	cohesin complex	RAD21	IDA		Human	PMID:11590136
Cellular Component	GO:0008278	cohesin complex	RAD21	IDA		Human	PMID:22628566
Cellular Component	GO:0008278	cohesin complex	Rad21	IDA		Mouse	MGI:MGI:1340883|PMID:10375619
Cellular Component	GO:0008278	cohesin complex	Rad21	IDA		Mouse	PMID:22419665
Cellular Component	GO:0000794	condensed nuclear chromosome	Rad21	IDA		Mouse	PMID:24797475
Cellular Component	GO:0016020	membrane	RAD21	HDA		Human	PMID:19946888
Cellular Component	GO:0030496	midbody	RAD21	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016363	nuclear matrix	RAD21	IDA		Human	PMID:11590136
Cellular Component	GO:0005654	nucleoplasm	RAD21	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Rad21	IDA		Mouse	MGI:MGI:1340883|PMID:10375619
Biological Process	GO:0003181	atrioventricular valve morphogenesis	rad21a	IMP	ZFIN:ZDB-MRPHLNO-070904-2	Zfish	PMID:26420840
Biological Process	GO:0008015	blood circulation	rad21a	IMP	ZFIN:ZDB-MRPHLNO-070904-2	Zfish	PMID:26420840
Biological Process	GO:0140588	chromatin looping	Rad21	IMP		Mouse	PMID:32328639
Biological Process	GO:0048703	embryonic viscerocranium morphogenesis	rad21a	IMP	ZFIN:ZDB-MRPHLNO-070904-2	Zfish	PMID:25378554
Biological Process	GO:0048703	embryonic viscerocranium morphogenesis	rad21a	IMP	ZFIN:ZDB-GENO-041006-4	Zfish	PMID:25378554
Biological Process	GO:0048484	enteric nervous system development	rad21a	IGI	ZFIN:ZDB-MRPHLNO-081020-2,ZFIN:ZDB-MRPHLNO-150506-2	Zfish	PMID:25575569
Biological Process	GO:0048484	enteric nervous system development	rad21a	IMP	ZFIN:ZDB-MRPHLNO-150506-2	Zfish	PMID:25575569
Biological Process	GO:0007507	heart development	rad21a	IMP	ZFIN:ZDB-MRPHLNO-070904-2	Zfish	PMID:26420840
Biological Process	GO:0007507	heart development	rad21a	IMP	ZFIN:ZDB-GENO-160303-1,ZFIN:ZDB-MRPHLNO-070904-2	Zfish	PMID:26420840
Biological Process	GO:0007507	heart development	rad21a	IMP	ZFIN:ZDB-GENO-100824-7	Zfish	PMID:26420840
Biological Process	GO:0001947	heart looping	rad21a	IMP	ZFIN:ZDB-MRPHLNO-070904-2	Zfish	PMID:26420840
Biological Process	GO:0007064	mitotic sister chromatid cohesion	rad21a	IMP	ZFIN:ZDB-GENO-070819-1	Zfish	PMID:17567667
Biological Process	GO:0007064	mitotic sister chromatid cohesion	rad21a	IMP	ZFIN:ZDB-MRPHLNO-070904-2	Zfish	PMID:17567667
Biological Process	GO:0010972	negative regulation of G2/M transition of mitotic cell cycle	Rad21	IMP		Mouse	MGI:MGI:1340883|PMID:10375619
Biological Process	GO:0045841	negative regulation of mitotic metaphase/anaphase transition	Rad21	IMP		Mouse	MGI:MGI:1340883|PMID:10375619
Biological Process	GO:0060037	pharyngeal system development	rad21a	IMP	ZFIN:ZDB-GENO-100824-7	Zfish	PMID:26420840
Biological Process	GO:0060037	pharyngeal system development	rad21a	IMP	ZFIN:ZDB-MRPHLNO-070904-2	Zfish	PMID:26420840
Biological Process	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	rad21a	IMP	ZFIN:ZDB-GENO-070819-1	Zfish	PMID:21637801
Biological Process	GO:0045876	positive regulation of sister chromatid cohesion	RAD21	IMP		Human	PMID:18499658
Biological Process	GO:0071168	protein localization to chromatin	RAD21	IMP		Human	PMID:21111234
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	RAD21	IDA		Human	PMID:19468298
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	rad21a	IMP	ZFIN:ZDB-GENO-100824-7	Zfish	PMID:22633399
Biological Process	GO:0003187	ventriculo bulbo valve morphogenesis	rad21a	IMP	ZFIN:ZDB-MRPHLNO-070904-2	Zfish	PMID:26420840

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern