Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RAD51B
  • Mouse genes Rad51b
  • Rat genes Rad51b
  • Zfish genes rad51b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rad51b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008094	ATP-dependent activity, acting on DNA	RAD51B	IDA		Human	PMID:12441335
Molecular Function	GO:0003690	double-stranded DNA binding	RAD51B	IDA		Human	PMID:12441335
Molecular Function	GO:0000400	four-way junction DNA binding	RAD51B	IDA		Human	PMID:20207730
Molecular Function	GO:0005515	protein binding	RAD51B	IPI	UniProtKB:O43502	Human	PMID:11751635
Molecular Function	GO:0005515	protein binding	RAD51B	IPI	UniProtKB:O75771	Human	PMID:11751635
Molecular Function	GO:0005515	protein binding	RAD51B	IPI	UniProtKB:O43502	Human	PMID:11842113
Molecular Function	GO:0005515	protein binding	RAD51B	IPI	UniProtKB:O75771	Human	PMID:11842113
Molecular Function	GO:0005515	protein binding	RAD51B	IPI	UniProtKB:Q6NVH7	Human	PMID:21965664
Molecular Function	GO:0005515	protein binding	RAD51B	IPI	UniProtKB:O43502	Human	PMID:24141787
Molecular Function	GO:0005515	protein binding	RAD51B	IPI	UniProtKB:Q8IZU0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RAD51B	IPI	UniProtKB:O43502	Human	PMID:28864920
Molecular Function	GO:0005515	protein binding	RAD51B	IPI	UniProtKB:Q6FHY5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RAD51B	IPI	UniProtKB:Q86UA6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RAD51B	IPI	UniProtKB:O43502	Human	PMID:34591612
Molecular Function	GO:0005515	protein binding	RAD51B	IPI	UniProtKB:O75771	Human	PMID:34591612
Molecular Function	GO:0005515	protein binding	RAD51B	IPI	UniProtKB:O43502	Human	PMID:9469824
Molecular Function	GO:0003697	single-stranded DNA binding	RAD51B	IDA		Human	PMID:12441335
Cellular Component	GO:0033063	Rad51B-Rad51C-Rad51D-XRCC2 complex	RAD51B	IDA		Human	PMID:11751635
Cellular Component	GO:0005657	replication fork	RAD51B	IDA		Human	PMID:20207730
Biological Process	GO:0001832	blastocyst growth	Rad51b	IMP	MGI:MGI:3621480	Mouse	PMID:10567591
Biological Process	GO:0000724	double-strand break repair via homologous recombination	RAD51B	IMP		Human	PMID:23149936
Biological Process	GO:0001701	in utero embryonic development	Rad51b	IMP	MGI:MGI:3621480	Mouse	PMID:10567591
Biological Process	GO:0001701	in utero embryonic development	Rad51b	IGI	MGI:MGI:98834	Mouse	PMID:10567591
Biological Process	GO:0008284	positive regulation of cell population proliferation	Rad51b	IMP	MGI:MGI:3621480	Mouse	PMID:10567591
Biological Process	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle	RAD51B	IMP		Human	PMID:23108668
Biological Process	GO:0061053	somite development	Rad51b	IMP	MGI:MGI:3621480	Mouse	PMID:10567591

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern