Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RAD51C
  • Mouse genes Rad51c
  • Rat genes Rad51c
  • Zfish genes rad51c
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rad51c

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008821	crossover junction DNA endonuclease activity	RAD51C	IMP		Human	PMID:14716019
Molecular Function	GO:0008821	crossover junction DNA endonuclease activity	Rad51c	IMP	MGI:MGI:3707422	Mouse	PMID:17312021
Molecular Function	GO:0008821	crossover junction DNA endonuclease activity	Rad51c	IMP	MGI:MGI:3707425	Mouse	PMID:17312021
Molecular Function	GO:0000400	four-way junction DNA binding	RAD51C	IDA		Human	PMID:20207730
Molecular Function	GO:0005515	protein binding	RAD51C	IPI	UniProtKB:O15315	Human	PMID:11751635
Molecular Function	GO:0005515	protein binding	RAD51C	IPI	UniProtKB:O43542	Human	PMID:11751635
Molecular Function	GO:0005515	protein binding	RAD51C	IPI	UniProtKB:O75771	Human	PMID:11751635
Molecular Function	GO:0005515	protein binding	RAD51C	IPI	UniProtKB:O15315	Human	PMID:11842113
Molecular Function	GO:0005515	protein binding	RAD51C	IPI	UniProtKB:O43542	Human	PMID:11842113
Molecular Function	GO:0005515	protein binding	RAD51C	IPI	UniProtKB:O43543	Human	PMID:11842113
Molecular Function	GO:0005515	protein binding	RAD51C	IPI	UniProtKB:O75771	Human	PMID:11842113
Molecular Function	GO:0005515	protein binding	RAD51C	IPI	UniProtKB:Q06609	Human	PMID:16395335
Molecular Function	GO:0005515	protein binding	RAD51C	IPI	UniProtKB:Q6NVH7	Human	PMID:21965664
Molecular Function	GO:0005515	protein binding	RAD51C	IPI	UniProtKB:O43542	Human	PMID:24005329
Molecular Function	GO:0005515	protein binding	RAD51C	IPI	UniProtKB:Q8TDG4	Human	PMID:24005329
Molecular Function	GO:0005515	protein binding	RAD51C	IPI	UniProtKB:O15315	Human	PMID:24141787
Molecular Function	GO:0005515	protein binding	RAD51C	IPI	UniProtKB:O43542	Human	PMID:24141787
Molecular Function	GO:0005515	protein binding	RAD51C	IPI	UniProtKB:O43543	Human	PMID:24141787
Molecular Function	GO:0005515	protein binding	RAD51C	IPI	UniProtKB:O75771	Human	PMID:24141787
Molecular Function	GO:0005515	protein binding	RAD51C	IPI	UniProtKB:Q06609	Human	PMID:24141787
Molecular Function	GO:0005515	protein binding	RAD51C	IPI	UniProtKB:Q86YC2	Human	PMID:24141787
Molecular Function	GO:0005515	protein binding	RAD51C	IPI	UniProtKB:O43542	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	RAD51C	IPI	UniProtKB:O43543	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	RAD51C	IPI	UniProtKB:O15315	Human	PMID:28864920
Molecular Function	GO:0005515	protein binding	RAD51C	IPI	UniProtKB:O43542	Human	PMID:28864920
Molecular Function	GO:0005515	protein binding	RAD51C	IPI	UniProtKB:O15315	Human	PMID:34591612
Molecular Function	GO:0005515	protein binding	RAD51C	IPI	UniProtKB:O43542	Human	PMID:34591612
Molecular Function	GO:0005515	protein binding	RAD51C	IPI	UniProtKB:O15315	Human	PMID:9469824
Molecular Function	GO:0005515	protein binding	RAD51C	IPI	UniProtKB:O43542	Human	PMID:9469824
Molecular Function	GO:0005515	protein binding	Rad51c	IPI	PR:Q9EP87	Mouse	PMID:19327148
Molecular Function	GO:0005515	protein binding	Rad51c	IPI	PR:O55230-1	Mouse	PMID:19327148
Cellular Component	GO:0030054	cell junction	RAD51C	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005737	cytoplasm	RAD51C	IDA		Human	PMID:16215984
Cellular Component	GO:0005829	cytosol	RAD51C	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	RAD51C	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	RAD51C	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	RAD51C	IDA		Human	PMID:20413593
Cellular Component	GO:0005654	nucleoplasm	RAD51C	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	RAD51C	IDA		Human	PMID:12966089
Cellular Component	GO:0005634	nucleus	RAD51C	IDA		Human	PMID:16215984
Cellular Component	GO:0005634	nucleus	Rad51c	IDA		Mouse	PMID:19327148
Cellular Component	GO:0048471	perinuclear region of cytoplasm	RAD51C	IDA		Human	PMID:16215984
Cellular Component	GO:0033063	Rad51B-Rad51C-Rad51D-XRCC2 complex	RAD51C	IDA		Human	PMID:11751635
Cellular Component	GO:0033065	Rad51C-XRCC3 complex	RAD51C	IDA		Human	PMID:11751635
Cellular Component	GO:0005657	replication fork	RAD51C	IDA		Human	PMID:20207730
Biological Process	GO:0006259	DNA metabolic process	Rad51c	IMP	MGI:MGI:3707425	Mouse	MGI:MGI:3703317|PMID:17312021
Biological Process	GO:0006310	DNA recombination	RAD51C	IDA		Human	PMID:19451272
Biological Process	GO:0006281	DNA repair	RAD51C	IDA		Human	PMID:19451272
Biological Process	GO:0000724	double-strand break repair via homologous recombination	RAD51C	IMP		Human	PMID:23149936
Biological Process	GO:0007066	female meiosis sister chromatid cohesion	Rad51c	IMP	MGI:MGI:3707425	Mouse	PMID:17312021
Biological Process	GO:0007066	female meiosis sister chromatid cohesion	Rad51c	IMP	MGI:MGI:3707422	Mouse	PMID:17312021
Biological Process	GO:0007141	male meiosis I	Rad51c	IMP	MGI:MGI:3707425	Mouse	PMID:17312021
Biological Process	GO:0007141	male meiosis I	Rad51c	IMP	MGI:MGI:3707422	Mouse	PMID:17312021
Biological Process	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle	RAD51C	IMP		Human	PMID:23108668
Biological Process	GO:0007131	reciprocal meiotic recombination	Rad51c	IMP	MGI:MGI:3707425	Mouse	PMID:17312021
Biological Process	GO:0007131	reciprocal meiotic recombination	Rad51c	IMP	MGI:MGI:3707422	Mouse	PMID:17312021
Biological Process	GO:0007283	spermatogenesis	Rad51c	IMP	MGI:MGI:3707422	Mouse	PMID:17312021
Biological Process	GO:0007283	spermatogenesis	Rad51c	IMP	MGI:MGI:3707425	Mouse	PMID:17312021
Biological Process	GO:0000722	telomere maintenance via recombination	Rad51c	IGI	UniProtKB:P02340	Mouse	MGI:MGI:5707585|PMID:21076401

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern