Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RAD9A
  • Mouse genes Rad9a
  • Rat genes Rad9a
  • Zfish genes rad9a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rad9a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008408	3'-5' exonuclease activity	RAD9A	IDA		Human	PMID:10713044
Molecular Function	GO:0019899	enzyme binding	RAD9A	IPI	UniProtKB:P27708	Human	PMID:15326225
Molecular Function	GO:0042826	histone deacetylase binding	RAD9A	IPI	UniProtKB:Q13547	Human	PMID:10846170
Molecular Function	GO:0005515	protein binding	RAD9A	IPI	UniProtKB:O60671	Human	PMID:10359610
Molecular Function	GO:0005515	protein binding	RAD9A	IPI	UniProtKB:O60921	Human	PMID:10359610
Molecular Function	GO:0005515	protein binding	RAD9A	IPI	UniProtKB:O75943	Human	PMID:10884395
Molecular Function	GO:0005515	protein binding	RAD9A	IPI	UniProtKB:Q07817	Human	PMID:11971963
Molecular Function	GO:0005515	protein binding	RAD9A	IPI	UniProtKB:Q6WBX8	Human	PMID:14500360
Molecular Function	GO:0005515	protein binding	RAD9A	IPI	UniProtKB:O60921	Human	PMID:14624239
Molecular Function	GO:0005515	protein binding	RAD9A	IPI	UniProtKB:P15927	Human	PMID:15897895
Molecular Function	GO:0005515	protein binding	RAD9A	IPI	UniProtKB:P27694	Human	PMID:15897895
Molecular Function	GO:0005515	protein binding	RAD9A	IPI	UniProtKB:O60921	Human	PMID:19464297
Molecular Function	GO:0005515	protein binding	RAD9A	IPI	UniProtKB:Q9BSD3	Human	PMID:21659603
Molecular Function	GO:0005515	protein binding	RAD9A	IPI	UniProtKB:O60921	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	RAD9A	IPI	UniProtKB:O60921	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Rad9a	IPI	PR:P10417	Mouse	PMID:15983387
Molecular Function	GO:0005515	protein binding	Rad9a	IPI	PR:Q4QY64	Mouse	PMID:15983387
Molecular Function	GO:0019901	protein kinase binding	RAD9A	IPI	UniProtKB:Q05655	Human	PMID:12628935
Molecular Function	GO:0017124	SH3 domain binding	RAD9A	IPI	UniProtKB:P00519	Human	PMID:11971963
Cellular Component	GO:0005737	cytoplasm	Rad9a	IDA		Mouse	PMID:15983387
Cellular Component	GO:0005654	nucleoplasm	RAD9A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	RAD9A	IDA		Human	PMID:12628935
Cellular Component	GO:0005634	nucleus	Rad9a	IDA		Mouse	PMID:15983387
Biological Process	GO:0071479	cellular response to ionizing radiation	RAD9A	IDA		Human	PMID:21659603
Biological Process	GO:0000077	DNA damage checkpoint signaling	RAD9A	IMP		Human	PMID:21659603
Biological Process	GO:0006974	DNA damage response	RAD9A	IDA		Human	PMID:9872989
Biological Process	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	Rad9a	IGI	MGI:MGI:2442925	Mouse	PMID:15983387
Biological Process	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	Rad9a	IMP		Mouse	PMID:15983387
Biological Process	GO:0031573	mitotic intra-S DNA damage checkpoint signaling	Rad9a	IGI	UniProtKB:P26306	Mouse	PMID:9766521
Biological Process	GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage	Rad9a	IGI	MGI:MGI:2442925	Mouse	PMID:15983387
Biological Process	GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage	Rad9a	IMP		Mouse	PMID:15983387

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern