Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Raf1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes RAF1
- Mouse genes Raf1
- Rat genes Raf1
- Zfish genes raf1a,raf1b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Raf1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0010856	adenylate cyclase activator activity	Raf1	IDA		Rat	PMID:15385642\|RGD:8554216
Molecular Function	GO:0008179	adenylate cyclase binding	Raf1	IPI	UniProtKB:Q03343	Rat	PMID:15385642\|RGD:8554216
Molecular Function	GO:0005524	ATP binding	Raf1	IDA		Rat	PMID:16272159\|RGD:2298675
Molecular Function	GO:0019899	enzyme binding	RAF1	IPI	UniProtKB:O60658	Human	PMID:23509299
Molecular Function	GO:0042802	identical protein binding	RAF1	IPI	UniProtKB:P04049	Human	PMID:17979178
Molecular Function	GO:0042802	identical protein binding	RAF1	IPI	UniProtKB:P04049	Human	PMID:20130576
Molecular Function	GO:0042802	identical protein binding	RAF1	IPI	UniProtKB:P04049	Human	PMID:22169110
Molecular Function	GO:0042802	identical protein binding	RAF1	IPI	UniProtKB:P04049	Human	PMID:22510884
Molecular Function	GO:0004709	MAP kinase kinase kinase activity	Raf1	IDA		Mouse	PMID:1322500
Molecular Function	GO:0004709	MAP kinase kinase kinase activity	Raf1	IDA		Mouse	PMID:12354753
Molecular Function	GO:0004709	MAP kinase kinase kinase activity	Raf1	IDA		Rat	PMID:10648842\|RGD:2298801
Molecular Function	GO:0004709	MAP kinase kinase kinase activity	Raf1	IDA		Rat	PMID:16272159\|RGD:2298675
Molecular Function	GO:0004709	MAP kinase kinase kinase activity	Raf1	IMP		Rat	PMID:16508002\|RGD:1580106
Molecular Function	GO:0004709	MAP kinase kinase kinase activity	Raf1	IDA		Rat	PMID:8603510\|RGD:1580670
Molecular Function	GO:0031434	mitogen-activated protein kinase kinase binding	Raf1	IMP		Rat	PMID:16508002\|RGD:1580106
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P61981	Human	PMID:10433554
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:Q9ESN9	Human	PMID:10523642
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:Q9ESN9-2	Human	PMID:10523642
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P27348	Human	PMID:11697890
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P31946	Human	PMID:11697890
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P31947	Human	PMID:11697890
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P61981	Human	PMID:11697890
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P62258	Human	PMID:11697890
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P63104	Human	PMID:11697890
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:Q04917	Human	PMID:11697890
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P36507	Human	PMID:11909642
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:O43482	Human	PMID:12620389
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P01112	Human	PMID:12620389
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P14618	Human	PMID:12620389
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P31327	Human	PMID:12620389
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P31946	Human	PMID:12620389
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P49368	Human	PMID:12620389
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:Q3ZCQ8	Human	PMID:12620389
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P63104	Human	PMID:14688280
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P31947	Human	PMID:15778465
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P53805-2	Human	PMID:15935327
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P67775	Human	PMID:16239230
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:Q13362	Human	PMID:16239230
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P63104	Human	PMID:16306228
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P08238	Human	PMID:16330544
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:O39474	Human	PMID:16405965
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:Q13177	Human	PMID:16837009
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P30086	Human	PMID:17097642
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P32883	Human	PMID:17229891
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:Q02750	Human	PMID:17724343
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:Q6TCH7	Human	PMID:17724343
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P08238	Human	PMID:17979178
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P63104	Human	PMID:17979178
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:Q02750	Human	PMID:17979178
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:Q04917	Human	PMID:17979178
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:Q16543	Human	PMID:17979178
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P11021	Human	PMID:18064632
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P01112	Human	PMID:18073111
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P01112	Human	PMID:18273062
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P01111	Human	PMID:18641128
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P63104	Human	PMID:19049963
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P01112	Human	PMID:19063885
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P32883	Human	PMID:19164755
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:Q02750	Human	PMID:19197339
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:Q96S96	Human	PMID:19197339
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P01112	Human	PMID:19222999
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P31946	Human	PMID:19595761
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P01112	Human	PMID:19696784
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P63104	Human	PMID:20052757
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P01111	Human	PMID:20080631
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P01112	Human	PMID:20080631
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P01116-2	Human	PMID:20080631
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P15056	Human	PMID:20130576
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P01112	Human	PMID:20133694
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P15056	Human	PMID:20141835
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P01112	Human	PMID:20178605
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:Q13526	Human	PMID:20179103
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:Q13526	Human	PMID:20179161
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P63104	Human	PMID:20679480
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P01116-2	Human	PMID:20802526
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P06400	Human	PMID:21139044
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P01120	Human	PMID:21457714
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P01111	Human	PMID:21478863
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P28301	Human	PMID:21536655
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P30086	Human	PMID:21831839
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P36507	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P01112	Human	PMID:22169110
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P15056	Human	PMID:22169110
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P15056	Human	PMID:22510884
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:Q5T0W9	Human	PMID:22886302
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:Q86UY5	Human	PMID:22886303
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P08238	Human	PMID:22939624
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:Q9Y4C4	Human	PMID:23327923
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P15056	Human	PMID:23680146
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P15056	Human	PMID:23934108
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:Q02750	Human	PMID:23934108
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P03495	Human	PMID:24008843
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:Q16543	Human	PMID:24189400
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P31946	Human	PMID:24255178
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:Q12968	Human	PMID:24330068
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:Q2M2I3	Human	PMID:24736947
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:Q86UY5	Human	PMID:24736947
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:Q9BQN1	Human	PMID:24736947
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:Q9H4H8	Human	PMID:24736947
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P36507	Human	PMID:24746704
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:Q02750	Human	PMID:24746704
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P01112	Human	PMID:24929361
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:Q13188	Human	PMID:24929361
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:O95816	Human	PMID:25036637
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P07900	Human	PMID:25036637
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:Q16543	Human	PMID:25036637
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:Q9UQ13	Human	PMID:25137548
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P15056	Human	PMID:25155755
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:Q02750	Human	PMID:25155755
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P01112	Human	PMID:25684575
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P01116	Human	PMID:25852190
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P27348	Human	PMID:25852190
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P31946	Human	PMID:25852190
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P31947	Human	PMID:25852190
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P61981	Human	PMID:25852190
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P62258	Human	PMID:25852190
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P63104	Human	PMID:25852190
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:Q04917	Human	PMID:25852190
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:Q3ZCQ8	Human	PMID:25852190
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P15056	Human	PMID:26466569
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:Q02750	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:Q04917	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P27348	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P61981	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:Q04917	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P01111	Human	PMID:30194290
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P01112	Human	PMID:30194290
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P01116	Human	PMID:30194290
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P63104	Human	PMID:31024343
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:O95816	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P01111	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P01116	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P07900	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P08238	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P15056	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P27348	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P31946	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P31947	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P36507	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P49368	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P61981	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P62258	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P63104	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:Q02750	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:Q04917	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:Q16543	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:Q3ZCQ8	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P01111	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P07900	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P08238	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P27348	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P31946	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P36507	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P61981	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P62258	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P63104	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:Q02750	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:Q04917	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:Q16543	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:Q14790	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P01112	Human	PMID:34591612
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P31947	Human	PMID:35044719
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P30304	Human	PMID:7644510
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P31946	Human	PMID:7644510
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P62258	Human	PMID:7644510
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P27348	Human	PMID:7760835
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P62834	Human	PMID:7791872
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P31946	Human	PMID:7882972
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P31946	Human	PMID:7935795
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P63104	Human	PMID:7935795
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P63104	Human	PMID:7939632
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P31946	Human	PMID:8085158
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P63104	Human	PMID:8085158
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P01112	Human	PMID:8332187
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P63104	Human	PMID:8601312
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P01112	Human	PMID:8670882
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P62834	Human	PMID:8756332
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P01112	Human	PMID:9144171
Molecular Function	GO:0005515	protein binding	RAF1	IPI	UniProtKB:P03406	Human	PMID:9624170
Molecular Function	GO:0005515	protein binding	Raf1	IPI	UniProtKB:P15056	Mouse	MGI:MGI:5426077\|PMID:22510884
Molecular Function	GO:0005515	protein binding	Raf1	IPI	UniProtKB:P32883-2	Mouse	MGI:MGI:3688344\|PMID:15102471
Molecular Function	GO:0005515	protein binding	Raf1	IPI	UniProtKB:Q8CFI0\|UniProtKB:Q9WVC6\|UniProtKB:Q9Z2S7-3	Mouse	MGI:MGI:6092647\|PMID:19380724
Molecular Function	GO:0005515	protein binding	Raf1	IPI	UniProtKB:P28028	Mouse	MGI:MGI:4457468\|PMID:20141835
Molecular Function	GO:0005515	protein binding	Raf1	IPI	UniProtKB:P28028	Mouse	MGI:MGI:5317969\|PMID:22169110
Molecular Function	GO:0005515	protein binding	Raf1	IPI	UniProtKB:P01111	Mouse	MGI:MGI:5927440\|PMID:21478863
Molecular Function	GO:0005515	protein binding	Raf1	IPI	PR:P70336	Mouse	PMID:16365167
Molecular Function	GO:0005515	protein binding	Raf1	IPI	PR:Q99JI6	Mouse	PMID:14712229
Molecular Function	GO:0005515	protein binding	Raf1	IPI	PR:Q9R1Z8	Mouse	PMID:15836771
Molecular Function	GO:0005515	protein binding	Raf1	IPI	UniProtKB:P29066	Rat	PMID:10725339\|RGD:13524618
Molecular Function	GO:0005515	protein binding	Raf1	IPI	RGD:2827	Rat	PMID:18514235\|RGD:2314841
Molecular Function	GO:0005515	protein binding	Raf1	IPI	UniProtKB:O08773	Rat	PMID:19319189\|RGD:8554645
Molecular Function	GO:0005515	protein binding	Raf1	IPI	UniProtKB:O08773	Rat	PMID:19878719\|RGD:8553779
Molecular Function	GO:0030295	protein kinase activator activity	Raf1	IMP		Mouse	PMID:18202127
Molecular Function	GO:0030295	protein kinase activator activity	Raf1	IMP		Mouse	PMID:20056832
Molecular Function	GO:0030295	protein kinase activator activity	Raf1	IDA		Mouse	PMID:1322500
Molecular Function	GO:0030295	protein kinase activator activity	Raf1	IDA		Mouse	PMID:12354753
Molecular Function	GO:0004674	protein serine/threonine kinase activity	RAF1	IDA		Human	PMID:19667065
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Raf1	IMP		Mouse	PMID:20056832
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Raf1	IMP		Mouse	PMID:18202127
Molecular Function	GO:0044877	protein-containing complex binding	Raf1	IPI	RGD:619908	Rat	PMID:16508002\|RGD:1580106
Molecular Function	GO:0031267	small GTPase binding	Raf1	IPI	PR:Q61411	Mouse	PMID:16954213
Cellular Component	GO:0005737	cytoplasm	RAF1	IDA		Human	PMID:17724343
Cellular Component	GO:0005737	cytoplasm	Raf1	IDA		Rat	PMID:19878719\|RGD:8553779
Cellular Component	GO:0005829	cytosol	RAF1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	RAF1	IDA		Human	PMID:16009725
Cellular Component	GO:0005794	Golgi apparatus	RAF1	IPI	UniProtKB:Q6TCH7	Human	PMID:17724343
Cellular Component	GO:0005886	plasma membrane	RAF1	IDA		Human	PMID:16009725
Cellular Component	GO:0005886	plasma membrane	RAF1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	RAF1	IDA		Human	PMID:17724343
Cellular Component	GO:0005886	plasma membrane	Raf1	IDA		Rat	PMID:19878719\|RGD:8553779
Cellular Component	GO:0031143	pseudopodium	Raf1	IDA		Mouse	MGI:MGI:2673740\|PMID:12821670
Biological Process	GO:0007190	activation of adenylate cyclase activity	RAF1	IDA		Human	PMID:15385642
Biological Process	GO:0030154	cell differentiation	Raf1	IGI	MGI:MGI:88190	Mouse	PMID:10704835
Biological Process	GO:0071550	death-inducing signaling complex assembly	Raf1	IMP	MGI:MGI:2388026	Mouse	PMID:16365167
Biological Process	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors	Raf1	IGI	MGI:MGI:95484	Mouse	PMID:16365167
Biological Process	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors	Raf1	IGI	MGI:MGI:99255	Mouse	PMID:16365167
Biological Process	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors	Raf1	IMP	MGI:MGI:2388026	Mouse	PMID:16365167
Biological Process	GO:0060324	face development	Raf1	IGI	MGI:MGI:88190	Mouse	PMID:18952847
Biological Process	GO:0007507	heart development	Raf1	IEP		Rat	PMID:9779826\|RGD:70317
Biological Process	GO:0007507	heart development	raf1a	IMP	ZFIN:ZDB-MRPHLNO-070904-8	Zfish	PMID:17603482
Biological Process	GO:0008286	insulin receptor signaling pathway	Raf1	IDA		Mouse	PMID:20056832
Biological Process	GO:0035773	insulin secretion involved in cellular response to glucose stimulus	Raf1	IMP	MGI:MGI:3497907	Mouse	PMID:21817126
Biological Process	GO:0048009	insulin-like growth factor receptor signaling pathway	Raf1	IDA		Mouse	PMID:33567274
Biological Process	GO:0045104	intermediate filament cytoskeleton organization	Raf1	IMP	MGI:MGI:2388026	Mouse	PMID:16365167
Biological Process	GO:0001678	intracellular glucose homeostasis	Raf1	IMP	MGI:MGI:3497907	Mouse	PMID:21817126
Biological Process	GO:0000165	MAPK cascade	Raf1	IDA		Rat	PMID:15886202\|RGD:1580668
Biological Process	GO:0000165	MAPK cascade	Raf1	IMP		Rat	PMID:17310240\|RGD:1626216
Biological Process	GO:0043066	negative regulation of apoptotic process	RAF1	IDA		Human	PMID:19667065
Biological Process	GO:0008285	negative regulation of cell population proliferation	RAF1	IDA		Human	PMID:9765203
Biological Process	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	Raf1	IGI	MGI:MGI:95484	Mouse	PMID:16365167
Biological Process	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	Raf1	IGI	MGI:MGI:99255	Mouse	PMID:16365167
Biological Process	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	Raf1	IMP	MGI:MGI:2388026	Mouse	PMID:16365167
Biological Process	GO:0031333	negative regulation of protein-containing complex assembly	RAF1	IDA		Human	PMID:19667065
Biological Process	GO:0048011	neurotrophin TRK receptor signaling pathway	Raf1	IMP		Mouse	PMID:9852579
Biological Process	GO:0043410	positive regulation of MAPK cascade	RAF1	IDA		Human	PMID:10644344
Biological Process	GO:0033138	positive regulation of peptidyl-serine phosphorylation	RAF1	IDA		Human	PMID:19667065
Biological Process	GO:0001934	positive regulation of protein phosphorylation	Raf1	IMP	MGI:MGI:3497907	Mouse	PMID:21817126
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Raf1	IMP	MGI:MGI:3497907	Mouse	PMID:21817126
Biological Process	GO:0006468	protein phosphorylation	Raf1	IDA		Rat	PMID:10648842\|RGD:2298801
Biological Process	GO:0006468	protein phosphorylation	Raf1	IDA		Rat	PMID:16272159\|RGD:2298675
Biological Process	GO:0006468	protein phosphorylation	Raf1	IMP		Rat	PMID:16508002\|RGD:1580106
Biological Process	GO:0043408	regulation of MAPK cascade	raf1a	IGI	ZFIN:ZDB-MRPHLNO-070519-1,ZFIN:ZDB-MRPHLNO-070519-2,ZFIN:ZDB-MRPHLNO-151208-5	Zfish	PMID:26280580
Biological Process	GO:0001666	response to hypoxia	Raf1	IDA		Rat	PMID:8603510\|RGD:1580670
Biological Process	GO:0035994	response to muscle stretch	Raf1	IMP		Mouse	PMID:20442316
Biological Process	GO:0035019	somatic stem cell population maintenance	Raf1	IGI	MGI:MGI:88190	Mouse	PMID:23022482
Biological Process	GO:0048538	thymus development	Raf1	IGI	MGI:MGI:88190	Mouse	PMID:18952847
Biological Process	GO:0030878	thyroid gland development	Raf1	IGI	MGI:MGI:88190	Mouse	PMID:18952847
Biological Process	GO:0044342	type B pancreatic cell proliferation	Raf1	IMP		Mouse	PMID:18202127

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.