Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Ramp2

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes RAMP2
- Mouse genes Ramp2
- Rat genes Ramp2
- Zfish genes ramp2
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ramp2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:1990409	adrenomedullin binding	RAMP2	IPI	UniProtKB:Q16602	Human	PMID:22102369
Molecular Function	GO:0001605	adrenomedullin receptor activity	RAMP2	IPI	UniProtKB:Q16602	Human	PMID:20074556
Molecular Function	GO:0001605	adrenomedullin receptor activity	RAMP2	IPI	UniProtKB:Q16602	Human	PMID:22102369
Molecular Function	GO:0001605	adrenomedullin receptor activity	RAMP2	IPI	UniProtKB:Q16602	Human	PMID:9620797
Molecular Function	GO:0097643	amylin receptor activity	RAMP2	IGI	UniProtKB:P12969:PRO_0000004122,UniProtKB:P30988\|UniProtKB:P30988,UniProtKB:P35318	Human	PMID:22500019
Molecular Function	GO:0015026	coreceptor activity	Ramp2	IDA		Mouse	PMID:10854696
Molecular Function	GO:0015026	coreceptor activity	Ramp2	IDA		Rat	PMID:11556887\|RGD:1299115
Molecular Function	GO:0005515	protein binding	RAMP2	IPI	UniProtKB:Q16602	Human	PMID:20596610
Molecular Function	GO:0005515	protein binding	RAMP2	IPI	UniProtKB:Q16602	Human	PMID:22102369
Molecular Function	GO:0005515	protein binding	RAMP2	IPI	UniProtKB:Q16602	Human	PMID:30115739
Molecular Function	GO:0005515	protein binding	RAMP2	IPI	UniProtKB:P80188	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RAMP2	IPI	UniProtKB:Q9UHD4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RAMP2	IPI	UniProtKB:P43145	Human	PMID:9620797
Cellular Component	GO:1903143	adrenomedullin receptor complex	RAMP2	IDA		Human	PMID:10882736
Cellular Component	GO:1903143	adrenomedullin receptor complex	RAMP2	IDA		Human	PMID:20074556
Cellular Component	GO:1903143	adrenomedullin receptor complex	RAMP2	IDA		Human	PMID:22102369
Cellular Component	GO:1903143	adrenomedullin receptor complex	RAMP2	IDA		Human	PMID:9620797
Cellular Component	GO:0150057	amylin receptor complex 2	RAMP2	IDA		Human	PMID:22500019
Cellular Component	GO:0009986	cell surface	RAMP2	IDA		Human	PMID:14722252
Cellular Component	GO:0005737	cytoplasm	RAMP2	IDA		Human	PMID:10882736
Cellular Component	GO:0005886	plasma membrane	RAMP2	IDA		Human	PMID:9620797
Cellular Component	GO:0043235	receptor complex	RAMP2	IDA		Human	PMID:15613468
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	RAMP2	IPI	UniProtKB:Q16602	Human	PMID:10882736
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	RAMP2	IPI	UniProtKB:Q16602	Human	PMID:20074556
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	RAMP2	IPI	UniProtKB:Q16602	Human	PMID:22102369
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	RAMP2	IGI	UniProtKB:P12969:PRO_0000004122,UniProtKB:P30988	Human	PMID:22500019
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	RAMP2	IGI	UniProtKB:P30988,UniProtKB:P35318	Human	PMID:22500019
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	RAMP2	IPI	UniProtKB:Q16602	Human	PMID:9620797
Biological Process	GO:0034333	adherens junction assembly	RAMP2	IDA		Human	PMID:18097473
Biological Process	GO:0034333	adherens junction assembly	Ramp2	IMP		Mouse	MGI:MGI:3772552\|PMID:18097473
Biological Process	GO:1990410	adrenomedullin receptor signaling pathway	RAMP2	IPI	UniProtKB:Q16602	Human	PMID:10882736
Biological Process	GO:1990410	adrenomedullin receptor signaling pathway	RAMP2	IPI	UniProtKB:Q16602	Human	PMID:20074556
Biological Process	GO:1990410	adrenomedullin receptor signaling pathway	RAMP2	IPI	UniProtKB:Q16602	Human	PMID:22102369
Biological Process	GO:1990410	adrenomedullin receptor signaling pathway	RAMP2	IPI	UniProtKB:Q16602	Human	PMID:9620797
Biological Process	GO:0097647	amylin receptor signaling pathway	RAMP2	IGI	UniProtKB:P12969:PRO_0000004122,UniProtKB:P30988\|UniProtKB:P30988,UniProtKB:P35318	Human	PMID:22500019
Biological Process	GO:0001525	angiogenesis	RAMP2	IDA		Human	PMID:20596610
Biological Process	GO:0070831	basement membrane assembly	Ramp2	IMP		Mouse	MGI:MGI:3772552\|PMID:18097473
Biological Process	GO:0070830	bicellular tight junction assembly	RAMP2	IDA		Human	PMID:18097473
Biological Process	GO:0070830	bicellular tight junction assembly	Ramp2	IMP		Mouse	MGI:MGI:3772552\|PMID:18097473
Biological Process	GO:0006816	calcium ion transport	RAMP2	IDA		Human	PMID:10882736
Biological Process	GO:0032870	cellular response to hormone stimulus	Ramp2	IEP		Rat	PMID:11549285\|RGD:1642709
Biological Process	GO:0035924	cellular response to vascular endothelial growth factor stimulus	Ramp2	IMP		Mouse	MGI:MGI:3772552\|PMID:18097473
Biological Process	GO:0007565	female pregnancy	Ramp2	IEP		Rat	PMID:12801991\|RGD:1642705
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	Ramp2	IPI	UniProtKB:P70160	Mouse	PMID:10854696
Biological Process	GO:0007507	heart development	Ramp2	IMP		Mouse	MGI:MGI:3772552\|PMID:18097473
Biological Process	GO:2000352	negative regulation of endothelial cell apoptotic process	RAMP2	IDA		Human	PMID:18097473
Biological Process	GO:2000352	negative regulation of endothelial cell apoptotic process	Ramp2	IMP		Mouse	MGI:MGI:3772552\|PMID:18097473
Biological Process	GO:0043116	negative regulation of vascular permeability	RAMP2	IDA		Human	PMID:18097473
Biological Process	GO:0043116	negative regulation of vascular permeability	Ramp2	IMP		Mouse	MGI:MGI:3772552\|PMID:18097473
Biological Process	GO:0045766	positive regulation of angiogenesis	Ramp2	IMP		Mouse	MGI:MGI:3772552\|PMID:18097473
Biological Process	GO:0010628	positive regulation of gene expression	RAMP2	IDA		Human	PMID:18097473
Biological Process	GO:0010628	positive regulation of gene expression	Ramp2	IMP		Mouse	MGI:MGI:3772552\|PMID:18097473
Biological Process	GO:0032092	positive regulation of protein binding	Ramp2	IDA		Rat	PMID:11556887\|RGD:1299115
Biological Process	GO:2001214	positive regulation of vasculogenesis	Ramp2	IMP		Mouse	MGI:MGI:3772552\|PMID:18097473
Biological Process	GO:0072659	protein localization to plasma membrane	RAMP2	IDA		Human	PMID:10882736
Biological Process	GO:0015031	protein transport	RAMP2	IDA		Human	PMID:10882736
Biological Process	GO:0015031	protein transport	RAMP2	IDA		Human	PMID:9620797
Biological Process	GO:0031623	receptor internalization	RAMP2	IDA		Human	PMID:10882736
Biological Process	GO:0031623	receptor internalization	RAMP2	IDA		Human	PMID:15613468
Biological Process	GO:0031623	receptor internalization	RAMP2	IDA		Human	PMID:20074556
Biological Process	GO:0031623	receptor internalization	Ramp2	IDA		Rat	PMID:15613468\|RGD:8554018
Biological Process	GO:0008217	regulation of blood pressure	Ramp2	IMP		Mouse	MGI:MGI:3772552\|PMID:18097473
Biological Process	GO:0032355	response to estradiol	Ramp2	IEP		Rat	PMID:15279908\|RGD:1642687
Biological Process	GO:0001666	response to hypoxia	Ramp2	IEP		Rat	PMID:17251392\|RGD:1625295
Biological Process	GO:0032570	response to progesterone	Ramp2	IEP		Rat	PMID:12801991\|RGD:1642705
Biological Process	GO:0002040	sprouting angiogenesis	Ramp2	IMP		Mouse	MGI:MGI:3772552\|PMID:18097473
Biological Process	GO:0097084	vascular associated smooth muscle cell development	Ramp2	IMP		Mouse	MGI:MGI:3772552\|PMID:18097473
Biological Process	GO:0001570	vasculogenesis	RAMP2	IMP		Human	PMID:16964401

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 08/02/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.