Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RAMP3
  • Mouse genes Ramp3
  • Rat genes Ramp3
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ramp3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001605	adrenomedullin receptor activity	RAMP3	IPI	UniProtKB:Q16602	Human	PMID:10882736
Molecular Function	GO:0097643	amylin receptor activity	RAMP3	IGI	UniProtKB:P10997:PRO_0000004106,UniProtKB:P30988	Human	PMID:22500019
Molecular Function	GO:0015026	coreceptor activity	Ramp3	IDA		Mouse	PMID:10854696
Molecular Function	GO:0015026	coreceptor activity	Ramp3	IDA		Rat	PMID:11556887|RGD:1299115
Molecular Function	GO:0005515	protein binding	RAMP3	IPI	UniProtKB:A6QP74	Human	PMID:15613468
Molecular Function	GO:0005515	protein binding	RAMP3	IPI	UniProtKB:P46459	Human	PMID:15613468
Molecular Function	GO:0005515	protein binding	RAMP3	IPI	UniProtKB:Q99527	Human	PMID:23674134
Molecular Function	GO:0005515	protein binding	RAMP3	IPI	UniProtKB:P26371	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RAMP3	IPI	UniProtKB:Q7Z3S9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RAMP3	IPI	UniProtKB:A8MQ03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RAMP3	IPI	UniProtKB:P0DPK4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RAMP3	IPI	UniProtKB:Q6L8G8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RAMP3	IPI	UniProtKB:Q6L8H2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RAMP3	IPI	UniProtKB:Q9BYQ3	Human	PMID:32296183
Cellular Component	GO:1903143	adrenomedullin receptor complex	RAMP3	IDA		Human	PMID:10882736
Cellular Component	GO:0150058	amylin receptor complex 3	RAMP3	IDA		Human	PMID:22500019
Cellular Component	GO:0009986	cell surface	RAMP3	IDA		Human	PMID:10882736
Cellular Component	GO:0009986	cell surface	RAMP3	IDA		Human	PMID:14722252
Cellular Component	GO:0005764	lysosome	RAMP3	IDA		Human	PMID:15613468
Cellular Component	GO:0005886	plasma membrane	RAMP3	IDA		Human	PMID:9620797
Cellular Component	GO:0005886	plasma membrane	RAMP3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	RAMP3	IDA		Human	PMID:15613468
Cellular Component	GO:0005886	plasma membrane	RAMP3	IDA		Human	PMID:23674134
Cellular Component	GO:0005886	plasma membrane	Ramp3	IDA		Mouse	MGI:MGI:5514109|PMID:23674134
Cellular Component	GO:0043235	receptor complex	RAMP3	IDA		Human	PMID:15613468
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	RAMP3	IPI	UniProtKB:Q16602	Human	PMID:10882736
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	RAMP3	IGI	ComplexPortal:CPX-1134,UniProtKB:P30988	Human	PMID:22500019
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	RAMP3	IGI	UniProtKB:P10997:PRO_0000004106,UniProtKB:P30988	Human	PMID:22500019
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	RAMP3	IGI	UniProtKB:P12969:PRO_0000004122,UniProtKB:P30988	Human	PMID:22500019
Biological Process	GO:1990410	adrenomedullin receptor signaling pathway	RAMP3	IPI	UniProtKB:Q16602	Human	PMID:10882736
Biological Process	GO:0097647	amylin receptor signaling pathway	RAMP3	IGI	ComplexPortal:CPX-1134,UniProtKB:P30988	Human	PMID:22500019
Biological Process	GO:0097647	amylin receptor signaling pathway	RAMP3	IGI	UniProtKB:P10997:PRO_0000004106,UniProtKB:P30988	Human	PMID:22500019
Biological Process	GO:0006816	calcium ion transport	RAMP3	IDA		Human	PMID:10882736
Biological Process	GO:0071392	cellular response to estradiol stimulus	Ramp3	IDA		Mouse	MGI:MGI:5514109|PMID:23674134
Biological Process	GO:0038041	cross-receptor inhibition within G protein-coupled receptor heterodimer	RAMP3	IPI	UniProtKB:P30988	Human	PMID:14722252
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	Ramp3	IPI	UniProtKB:P97297	Mouse	PMID:10854696
Biological Process	GO:0086103	G protein-coupled receptor signaling pathway involved in heart process	Ramp3	IMP		Mouse	MGI:MGI:5514109|PMID:23674134
Biological Process	GO:1905665	positive regulation of calcium ion import across plasma membrane	RAMP3	IGI	ComplexPortal:CPX-1134,UniProtKB:P30988	Human	PMID:22500019
Biological Process	GO:1905665	positive regulation of calcium ion import across plasma membrane	RAMP3	IGI	UniProtKB:P10997:PRO_0000004106,UniProtKB:P30988	Human	PMID:22500019
Biological Process	GO:0010942	positive regulation of cell death	RAMP3	IGI	ComplexPortal:CPX-1134,UniProtKB:P30988	Human	PMID:22500019
Biological Process	GO:0010942	positive regulation of cell death	RAMP3	IGI	UniProtKB:P10997:PRO_0000004106,UniProtKB:P30988	Human	PMID:22500019
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	RAMP3	IGI	ComplexPortal:CPX-1134,UniProtKB:P30988	Human	PMID:22500019
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	RAMP3	IGI	UniProtKB:P10997:PRO_0000004106,UniProtKB:P30988	Human	PMID:22500019
Biological Process	GO:0010628	positive regulation of gene expression	RAMP3	IGI	ComplexPortal:CPX-1134,UniProtKB:P30988	Human	PMID:22500019
Biological Process	GO:0010628	positive regulation of gene expression	RAMP3	IGI	UniProtKB:P10997:PRO_0000004106,UniProtKB:P30988	Human	PMID:22500019
Biological Process	GO:0033138	positive regulation of peptidyl-serine phosphorylation	RAMP3	IGI	ComplexPortal:CPX-1134,UniProtKB:P30988	Human	PMID:22500019
Biological Process	GO:0033138	positive regulation of peptidyl-serine phosphorylation	RAMP3	IGI	UniProtKB:P10997:PRO_0000004106,UniProtKB:P30988	Human	PMID:22500019
Biological Process	GO:0010739	positive regulation of protein kinase A signaling	RAMP3	IGI	ComplexPortal:CPX-1134,UniProtKB:P30988	Human	PMID:22500019
Biological Process	GO:0010739	positive regulation of protein kinase A signaling	RAMP3	IGI	UniProtKB:P10997:PRO_0000004106,UniProtKB:P30988	Human	PMID:22500019
Biological Process	GO:0051897	positive regulation of protein kinase B signaling	RAMP3	IGI	ComplexPortal:CPX-1134,UniProtKB:P30988	Human	PMID:22500019
Biological Process	GO:0051897	positive regulation of protein kinase B signaling	RAMP3	IGI	UniProtKB:P10997:PRO_0000004106,UniProtKB:P30988	Human	PMID:22500019
Biological Process	GO:1903078	positive regulation of protein localization to plasma membrane	RAMP3	IDA		Human	PMID:23674134
Biological Process	GO:0001921	positive regulation of receptor recycling	RAMP3	IDA		Human	PMID:15613468
Biological Process	GO:0072659	protein localization to plasma membrane	RAMP3	IDA		Human	PMID:10882736
Biological Process	GO:0015031	protein transport	RAMP3	IDA		Human	PMID:10882736
Biological Process	GO:0015031	protein transport	RAMP3	IDA		Human	PMID:9620797
Biological Process	GO:0031623	receptor internalization	RAMP3	IDA		Human	PMID:10882736
Biological Process	GO:0031623	receptor internalization	RAMP3	IDA		Human	PMID:15613468
Biological Process	GO:1904645	response to amyloid-beta	RAMP3	IGI	UniProtKB:P30988	Human	PMID:22500019

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern