Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RANGAP1
  • Mouse genes Rangap1
  • Rat genes Rangap1
  • Zfish genes rangap1a,rangap1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rangap1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045296	cadherin binding	RANGAP1	HDA		Human	PMID:25468996
Molecular Function	GO:0005096	GTPase activator activity	RANGAP1	IDA		Human	PMID:16428860
Molecular Function	GO:0005515	protein binding	RANGAP1	IPI	UniProtKB:P49792,UniProtKB:Q9UBU9,UniProtKB:Q9UKK6	Human	PMID:14729961
Molecular Function	GO:0005515	protein binding	RANGAP1	IPI	UniProtKB:P49792	Human	PMID:16204249
Molecular Function	GO:0005515	protein binding	RANGAP1	IPI	UniProtKB:P63165	Human	PMID:16732283
Molecular Function	GO:0005515	protein binding	RANGAP1	IPI	UniProtKB:P63279	Human	PMID:16732283
Molecular Function	GO:0005515	protein binding	RANGAP1	IPI	UniProtKB:P63165	Human	PMID:17000644
Molecular Function	GO:0005515	protein binding	RANGAP1	IPI	UniProtKB:P63165	Human	PMID:17036045
Molecular Function	GO:0005515	protein binding	RANGAP1	IPI	UniProtKB:P63279	Human	PMID:17036045
Molecular Function	GO:0005515	protein binding	RANGAP1	IPI	UniProtKB:P63165	Human	PMID:17099698
Molecular Function	GO:0005515	protein binding	RANGAP1	IPI	UniProtKB:P63165	Human	PMID:17099700
Molecular Function	GO:0005515	protein binding	RANGAP1	IPI	UniProtKB:Q9Y4K3	Human	PMID:18093978
Molecular Function	GO:0005515	protein binding	RANGAP1	IPI	UniProtKB:P63279	Human	PMID:19549727
Molecular Function	GO:0005515	protein binding	RANGAP1	IPI	UniProtKB:P63165	Human	PMID:20414307
Molecular Function	GO:0005515	protein binding	RANGAP1	IPI	UniProtKB:P63279	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	RANGAP1	IPI	UniProtKB:P49792	Human	PMID:22194619
Molecular Function	GO:0005515	protein binding	RANGAP1	IPI	UniProtKB:P63165	Human	PMID:22194619
Molecular Function	GO:0005515	protein binding	RANGAP1	IPI	UniProtKB:P63279	Human	PMID:22194619
Molecular Function	GO:0005515	protein binding	RANGAP1	IPI	UniProtKB:P63165	Human	PMID:23395904
Molecular Function	GO:0005515	protein binding	RANGAP1	IPI	UniProtKB:P63279	Human	PMID:23395904
Molecular Function	GO:0005515	protein binding	RANGAP1	IPI	UniProtKB:P42858	Human	PMID:25959826
Molecular Function	GO:0005515	protein binding	RANGAP1	IPI	UniProtKB:P63279	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	RANGAP1	IPI	UniProtKB:P63279	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	RANGAP1	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Rangap1	IPI	RGD:1560047	Rat	PMID:9019411|RGD:9835352
Molecular Function	GO:0003723	RNA binding	RANGAP1	IDA		Human	PMID:26308891
Molecular Function	GO:0031267	small GTPase binding	RANGAP1	IPI	UniProtKB:P62826	Human	PMID:16428860
Molecular Function	GO:0031267	small GTPase binding	Rangap1	IDA		Rat	PMID:8978815|RGD:9835354
Molecular Function	GO:0031625	ubiquitin protein ligase binding	Rangap1	IPI	RGD:3926	Rat	PMID:9497385|RGD:9835353
Cellular Component	GO:0016235	aggresome	RANGAP1	IDA		Human	GO_REF:0000052
Cellular Component	GO:1904115	axon cytoplasm	Rangap1	IDA		Rat	PMID:18667152|RGD:9835000
Cellular Component	GO:0005737	cytoplasm	Rangap1	IDA		Mouse	PMID:15923632
Cellular Component	GO:0005737	cytoplasm	Rangap1	IDA		Rat	PMID:22811487|RGD:9835351
Cellular Component	GO:1990723	cytoplasmic periphery of the nuclear pore complex	Rangap1	IDA		Rat	PMID:9019411|RGD:9835352
Cellular Component	GO:0005829	cytosol	RANGAP1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	Rangap1	IDA		Rat	PMID:8978815|RGD:9835354
Cellular Component	GO:0030425	dendrite	Rangap1	IDA		Rat	PMID:18667152|RGD:9835000
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	RANGAP1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0000776	kinetochore	RANGAP1	IDA		Human	PMID:17363900
Cellular Component	GO:0072686	mitotic spindle	Rangap1	IDA		Rat	PMID:8978815|RGD:9835354
Cellular Component	GO:0005635	nuclear envelope	RANGAP1	IDA		Human	PMID:25468996
Cellular Component	GO:0031965	nuclear membrane	RANGAP1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005643	nuclear pore	Rangap1	IDA		Rat	PMID:22811487|RGD:9835351
Cellular Component	GO:0044614	nuclear pore cytoplasmic filaments	Rangap1	IDA		Rat	PMID:8978815|RGD:9835354
Cellular Component	GO:0005634	nucleus	Rangap1	IDA		Rat	PMID:22811487|RGD:9835351
Cellular Component	GO:0048471	perinuclear region of cytoplasm	RANGAP1	IDA		Human	PMID:26308891
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Rangap1	IDA		Mouse	PMID:15923632
Cellular Component	GO:0106068	SUMO ligase complex	RANGAP1	IPI		Human	PMID:22194619
Biological Process	GO:0090630	activation of GTPase activity	RANGAP1	IDA		Human	PMID:16428860
Biological Process	GO:0071375	cellular response to peptide hormone stimulus	Rangap1	IDA		Rat	PMID:22811487|RGD:9835351
Biological Process	GO:1904117	cellular response to vasopressin	Rangap1	IEP		Rat	PMID:22811487|RGD:9835351
Biological Process	GO:0046826	negative regulation of protein export from nucleus	RANGAP1	IDA		Human	PMID:16449645
Biological Process	GO:0051168	nuclear export	RANGAP1	EXP		Human	PMID:27160050
Biological Process	GO:0051168	nuclear export	Rangap1	EXP		Mouse	MGI:MGI:6867121|PMID:27160050
Biological Process	GO:0016925	protein sumoylation	RANGAP1	IDA		Human	PMID:22194619
Biological Process	GO:0048678	response to axon injury	Rangap1	IEP		Rat	PMID:18667152|RGD:9835000

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern