Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RAP1GAP2
  • Mouse genes Rap1gap2
  • Rat genes Rap1gap2
  • Zfish genes rap1gap2a,rap1gap2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rap1gap2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005096	GTPase activator activity	RAP1GAP2	EXP		Human	PMID:16076873
Molecular Function	GO:0005096	GTPase activator activity	Rap1gap2	IDA		Mouse	PMID:22732430
Molecular Function	GO:0005515	protein binding	RAP1GAP2	IPI	UniProtKB:Q99N50	Human	PMID:24284068
Molecular Function	GO:0005515	protein binding	RAP1GAP2	IPI	UniProtKB:Q6FHY5	Human	PMID:32296183
Cellular Component	GO:0005813	centrosome	RAP1GAP2	IDA		Human	PMID:21399614
Cellular Component	GO:0005737	cytoplasm	Rap1gap2	IDA		Mouse	PMID:22732430
Cellular Component	GO:0005829	cytosol	RAP1GAP2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043005	neuron projection	Rap1gap2	IDA		Mouse	PMID:22732430
Cellular Component	GO:0031965	nuclear membrane	RAP1GAP2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	RAP1GAP2	IGI	UniProtKB:Q99N50	Human	PMID:24284068
Biological Process	GO:0010977	negative regulation of neuron projection development	Rap1gap2	IMP		Mouse	PMID:22732430
Biological Process	GO:0010977	negative regulation of neuron projection development	Rap1gap2	IDA		Mouse	PMID:22732430
Biological Process	GO:0008361	regulation of cell size	RAP1GAP2	IGI	UniProtKB:Q99N50	Human	PMID:24284068
Biological Process	GO:0008361	regulation of cell size	RAP1GAP2	IMP		Human	PMID:24284068

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern