Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RAP1GDS1
  • Mouse genes Rap1gds1
  • Rat genes Rap1gds1
  • Zfish genes rap1gds1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rap1gds1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0030695	GTPase regulator activity	Rap1gds1	IDA		Mouse	PMID:26975711
Molecular Function	GO:0030695	GTPase regulator activity	Rap1gds1	IMP	MGI:MGI:3613572	Mouse	PMID:26975711
Molecular Function	GO:0030695	GTPase regulator activity	Rap1gds1	IMP		Mouse	PMID:26975711
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	RAP1GDS1	IDA		Human	PMID:21242305
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	RAP1GDS1	IDA		Human	PMID:28630045
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	RAP1GDS1	IDA		Human	PMID:30190425
Molecular Function	GO:0005515	protein binding	RAP1GDS1	IPI	UniProtKB:P01116	Human	PMID:24415755
Molecular Function	GO:0005515	protein binding	RAP1GDS1	IPI	UniProtKB:P61224	Human	PMID:24415755
Molecular Function	GO:0005515	protein binding	RAP1GDS1	IPI	UniProtKB:Q9NS73-5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RAP1GDS1	IPI	UniProtKB:Q9UF11	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RAP1GDS1	IPI	UniProtKB:P61586	Human	PMID:28630045
Molecular Function	GO:0005515	protein binding	RAP1GDS1	IPI	UniProtKB:P61586	Human	PMID:30190425
Molecular Function	GO:0005515	protein binding	RAP1GDS1	IPI	UniProtKB:Q5HYI8	Human	PMID:31406347
Molecular Function	GO:0005515	protein binding	RAP1GDS1	IPI	UniProtKB:P0DTD1:PRO_0000449620	Human	PMID:32353859
Molecular Function	GO:0005515	protein binding	RAP1GDS1	IPI	UniProtKB:P0DTD1:PRO_0000449620	Human	PMID:32838362
Molecular Function	GO:0005515	protein binding	RAP1GDS1	IPI	UniProtKB:P0DTD1:PRO_0000449620	Human	PMID:33060197
Molecular Function	GO:0005515	protein binding	RAP1GDS1	IPI	UniProtKB:P0DTD1:PRO_0000449620	Human	PMID:34159380
Cellular Component	GO:0005829	cytosol	RAP1GDS1	IDA		Human	PMID:24349085
Cellular Component	GO:0005783	endoplasmic reticulum	RAP1GDS1	IDA		Human	PMID:24349085
Cellular Component	GO:0070062	extracellular exosome	RAP1GDS1	HDA		Human	PMID:19056867
Cellular Component	GO:0005615	extracellular space	Rap1gds1	IDA		Mouse	PMID:26975711
Cellular Component	GO:0005739	mitochondrion	RAP1GDS1	IDA		Human	PMID:24349085
Cellular Component	GO:0005634	nucleus	RAP1GDS1	IDA		Human	PMID:12551911
Biological Process	GO:0086098	angiotensin-activated signaling pathway involved in heart process	Rap1gds1	IMP	MGI:MGI:3613572	Mouse	PMID:29921611
Biological Process	GO:0086098	angiotensin-activated signaling pathway involved in heart process	Rap1gds1	IMP	MGI:MGI:3613572	Mouse	PMID:26975711
Biological Process	GO:0080120	CAAX-box protein maturation	RAP1GDS1	IMP		Human	PMID:20709748
Biological Process	GO:0003300	cardiac muscle hypertrophy	Rap1gds1	IMP	MGI:MGI:3613572	Mouse	PMID:26975711
Biological Process	GO:0002534	cytokine production involved in inflammatory response	Rap1gds1	IMP	MGI:MGI:3613572	Mouse	PMID:29921611
Biological Process	GO:0002534	cytokine production involved in inflammatory response	Rap1gds1	IMP	MGI:MGI:3613572	Mouse	PMID:26975711
Biological Process	GO:0031034	myosin filament assembly	Rap1gds1	IMP		Rat	PMID:18348285|RGD:2314690
Biological Process	GO:0032471	negative regulation of endoplasmic reticulum calcium ion concentration	RAP1GDS1	IMP		Human	PMID:24349085
Biological Process	GO:0034260	negative regulation of GTPase activity	Rap1gds1	IMP	MGI:MGI:3613572	Mouse	PMID:29921611
Biological Process	GO:0034260	negative regulation of GTPase activity	Rap1gds1	IMP	MGI:MGI:3613572	Mouse	PMID:26975711
Biological Process	GO:0034260	negative regulation of GTPase activity	Rap1gds1	IDA		Mouse	PMID:26975711
Biological Process	GO:0034260	negative regulation of GTPase activity	Rap1gds1	IMP		Mouse	PMID:26975711
Biological Process	GO:0043547	positive regulation of GTPase activity	Rap1gds1	IMP		Rat	PMID:18348285|RGD:2314690
Biological Process	GO:0051561	positive regulation of mitochondrial calcium ion concentration	RAP1GDS1	IMP		Human	PMID:24349085
Biological Process	GO:0034504	protein localization to nucleus	RAP1GDS1	IMP		Human	PMID:12551911
Biological Process	GO:0070376	regulation of ERK5 cascade	Rap1gds1	IMP	MGI:MGI:3613572	Mouse	PMID:26975711
Biological Process	GO:0070376	regulation of ERK5 cascade	Rap1gds1	IMP		Mouse	PMID:26975711
Biological Process	GO:1904464	regulation of matrix metallopeptidase secretion	Rap1gds1	IMP	MGI:MGI:3613572	Mouse	PMID:29921611
Biological Process	GO:0010821	regulation of mitochondrion organization	RAP1GDS1	IMP		Human	PMID:27716788
Biological Process	GO:0036273	response to statin	Rap1gds1	IMP	MGI:MGI:3613572	Mouse	PMID:26975711
Biological Process	GO:0014829	vascular associated smooth muscle contraction	Rap1gds1	IMP		Rat	PMID:18348285|RGD:2314690

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern