Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RAP2C
  • Mouse genes Rap2c
  • Rat genes Rap2c
  • Zfish genes rap2c
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rap2c

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019003	GDP binding	RAP2C	IDA		Human	PMID:16213650
Molecular Function	GO:0005525	GTP binding	RAP2C	IDA		Human	PMID:16213650
Molecular Function	GO:0005515	protein binding	RAP2C	IPI	UniProtKB:P55196	Human	PMID:23885123
Molecular Function	GO:0005515	protein binding	RAP2C	IPI	UniProtKB:P52306-5	Human	PMID:32296183
Molecular Function	GO:0003713	transcription coactivator activity	RAP2C	IDA		Human	PMID:17447155
Cellular Component	GO:0005923	bicellular tight junction	RAP2C	IDA		Human	PMID:23885123
Cellular Component	GO:0044291	cell-cell contact zone	RAP2C	IDA		Human	PMID:23885123
Cellular Component	GO:0005737	cytoplasm	RAP2C	IDA		Human	PMID:17447155
Cellular Component	GO:0005829	cytosol	Rap2c	IDA		Mouse	PMID:19061864
Cellular Component	GO:0070062	extracellular exosome	RAP2C	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	RAP2C	HDA		Human	PMID:20458337
Cellular Component	GO:0016020	membrane	Rap2c	IDA		Mouse	PMID:19061864
Cellular Component	GO:0005886	plasma membrane	RAP2C	IDA		Human	PMID:16213650
Cellular Component	GO:0055037	recycling endosome	Rap2c	IDA		Mouse	PMID:19061864
Cellular Component	GO:0055038	recycling endosome membrane	Rap2c	IDA		Mouse	MGI:MGI:3822406|PMID:19061864
Biological Process	GO:0090557	establishment of endothelial intestinal barrier	RAP2C	IGI	UniProtKB:Q9Y624	Human	PMID:23885123
Biological Process	GO:0090557	establishment of endothelial intestinal barrier	RAP2C	IMP		Human	PMID:23885123
Biological Process	GO:0030336	negative regulation of cell migration	Rap2c	IDA		Mouse	PMID:19061864
Biological Process	GO:0031954	positive regulation of protein autophosphorylation	Rap2c	IDA		Mouse	PMID:19061864
Biological Process	GO:0032486	Rap protein signal transduction	Rap2c	IDA		Mouse	MGI:MGI:3822406|PMID:19061864
Biological Process	GO:0061097	regulation of protein tyrosine kinase activity	Rap2c	IDA		Mouse	MGI:MGI:3822406|PMID:19061864

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern