Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RAPSN
  • Mouse genes Rapsn
  • Rat genes Rapsn
  • Zfish genes rapsn
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rapsn

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0033130	acetylcholine receptor binding	RAPSN	IDA		Human	PMID:18420419
Molecular Function	GO:0033130	acetylcholine receptor binding	Rapsn	IPI	MGI:MGI:1202403	Mouse	PMID:18420419
Molecular Function	GO:0035255	ionotropic glutamate receptor binding	Rapsn	IPI	RGD:621531	Rat	PMID:19918122|RGD:4107718
Molecular Function	GO:0098879	structural constituent of postsynaptic specialization	Rapsn	IDA		Mouse	PMID:27839998
Molecular Function	GO:0098879	structural constituent of postsynaptic specialization	Rapsn	IMP		Mouse	PMID:27839998
Molecular Function	GO:0098879	structural constituent of postsynaptic specialization	Rapsn	IPI		Mouse	PMID:27839998
Cellular Component	GO:0005813	centrosome	RAPSN	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	RAPSN	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005794	Golgi apparatus	Rapsn	IDA		Mouse	PMID:12388596
Cellular Component	GO:0016020	membrane	Rapsn	IDA		Mouse	PMID:20053883
Cellular Component	GO:0031594	neuromuscular junction	Rapsn	IDA		Mouse	PMID:8416841
Cellular Component	GO:0031594	neuromuscular junction	Rapsn	IDA		Mouse	PMID:20053883
Cellular Component	GO:0031594	neuromuscular junction	Rapsn	IDA		Mouse	PMID:17119023
Cellular Component	GO:0031594	neuromuscular junction	Rapsn	IDA		Mouse	PMID:27225759
Cellular Component	GO:0031594	neuromuscular junction	Rapsn	IMP		Mouse	PMID:27225759
Cellular Component	GO:0031594	neuromuscular junction	Rapsn	IDA		Mouse	PMID:27839998
Cellular Component	GO:0031594	neuromuscular junction	Rapsn	IMP		Mouse	PMID:27839998
Cellular Component	GO:0031594	neuromuscular junction	Rapsn	IPI		Mouse	PMID:27839998
Cellular Component	GO:0031594	neuromuscular junction	Rapsn	IDA		Rat	PMID:19344765|RGD:8549750
Cellular Component	GO:0005886	plasma membrane	RAPSN	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	Rapsn	IDA		Mouse	PMID:12388596
Cellular Component	GO:0099634	postsynaptic specialization membrane	Rapsn	IDA		Mouse	PMID:27225759
Cellular Component	GO:0099634	postsynaptic specialization membrane	Rapsn	IMP		Mouse	PMID:27225759
Cellular Component	GO:0045202	synapse	Rapsn	IDA		Mouse	PMID:20053883
Cellular Component	GO:0045202	synapse	rapsn	IMP	ZFIN:ZDB-GENO-980202-1513	Zfish	PMID:27798141|ZFIN:ZDB-PUB-161101-4
Biological Process	GO:0007268	chemical synaptic transmission	rapsn	IMP	ZFIN:ZDB-GENO-980202-1513	Zfish	PMID:27798141
Biological Process	GO:1903540	establishment of protein localization to postsynaptic membrane	Rapsn	IMP		Rat	PMID:19344765|RGD:8549750
Biological Process	GO:0098880	maintenance of postsynaptic specialization structure	Rapsn	IPI		Mouse	MGI:MGI:6369184|PMID:27839998
Biological Process	GO:0097049	motor neuron apoptotic process	Rapsn	IMP	MGI:MGI:2148091	Mouse	PMID:11312299
Biological Process	GO:0099645	neurotransmitter receptor localization to postsynaptic specialization membrane	Rapsn	IDA		Mouse	PMID:27839998
Biological Process	GO:0099645	neurotransmitter receptor localization to postsynaptic specialization membrane	Rapsn	IPI		Mouse	PMID:27839998
Biological Process	GO:0099645	neurotransmitter receptor localization to postsynaptic specialization membrane	Rapsn	IMP		Mouse	PMID:27839998
Biological Process	GO:2000673	positive regulation of motor neuron apoptotic process	Rapsn	IMP	MGI:MGI:2148091	Mouse	PMID:11312299
Biological Process	GO:1900075	positive regulation of neuromuscular synaptic transmission	Rapsn	IMP		Rat	PMID:19344765|RGD:8549750
Biological Process	GO:0099173	postsynapse organization	Rapsn	IPI		Mouse	MGI:MGI:6369184|PMID:27839998
Biological Process	GO:1901626	regulation of postsynaptic membrane organization	Rapsn	IMP		Rat	PMID:19344765|RGD:8549750
Biological Process	GO:0007416	synapse assembly	rapsn	IMP		Zfish	PMID:22623681
Biological Process	GO:0007271	synaptic transmission, cholinergic	RAPSN	IGI	UniProtKB:Q9GZZ6	Human	PMID:18420419

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern