Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RARB
  • Mouse genes Rarb
  • Rat genes Rarb
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rarb

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Rarb	IDA		Mouse	PMID:8152920
Molecular Function	GO:1901363	heterocyclic compound binding	Rarb	IDA		Rat	PMID:19100254|RGD:2314252
Molecular Function	GO:0046965	nuclear retinoid X receptor binding	Rarb	IPI	RGD:3610	Rat	PMID:15234273|RGD:5688233
Molecular Function	GO:0005515	protein binding	Rarb	IPI	UniProtKB:Q8C0D7	Mouse	MGI:MGI:4455093|PMID:20211142
Molecular Function	GO:0005515	protein binding	Rarb	IPI	UniProtKB:Q8C0D7	Mouse	MGI:MGI:6695686|PMID:31420607
Molecular Function	GO:0005515	protein binding	Rarb	IPI	RGD:1309046	Rat	PMID:15234273|RGD:5688233
Molecular Function	GO:0005515	protein binding	Rarb	IPI	RGD:1310293	Rat	PMID:15234273|RGD:5688233
Molecular Function	GO:0005515	protein binding	Rarb	IPI	RGD:3612	Rat	PMID:15234273|RGD:5688233
Molecular Function	GO:0005515	protein binding	Rarb	IPI	RGD:620108	Rat	PMID:15234273|RGD:5688233
Molecular Function	GO:0044877	protein-containing complex binding	Rarb	IPI	RGD:1309046|RGD:620108|RGD:3610	Rat	PMID:15234273|RGD:5688233
Molecular Function	GO:0043565	sequence-specific DNA binding	Rarb	IGI	MGI:MGI:98216	Mouse	PMID:7823919
Molecular Function	GO:0043565	sequence-specific DNA binding	Rarb	IGI	MGI:MGI:98215	Mouse	PMID:7823919
Molecular Function	GO:0043565	sequence-specific DNA binding	Rarb	IGI	MGI:MGI:98214	Mouse	PMID:7823919
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	RARB	IDA		Human	PMID:28473536
Cellular Component	GO:0005654	nucleoplasm	RARB	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	RARB	IDA		Human	PMID:18845237
Cellular Component	GO:0005634	nucleus	Rarb	IDA		Rat	PMID:15234273|RGD:5688233
Cellular Component	GO:0005634	nucleus	Rarb	IDA		Rat	PMID:7581005|RGD:6771324
Biological Process	GO:0006915	apoptotic process	Rarb	IGI	MGI:MGI:97858	Mouse	PMID:16207763
Biological Process	GO:0060348	bone development	Rarb	IGI	MGI:MGI:97858	Mouse	PMID:7607067
Biological Process	GO:0008283	cell population proliferation	Rarb	IGI	MGI:MGI:97858	Mouse	PMID:10075839
Biological Process	GO:0048566	embryonic digestive tract development	RARB	IMP		Human	PMID:19443732
Biological Process	GO:0048048	embryonic eye morphogenesis	Rarb	IGI	MGI:MGI:97858	Mouse	PMID:16207763
Biological Process	GO:0035116	embryonic hindlimb morphogenesis	Rarb	IGI	MGI:MGI:97858	Mouse	PMID:10075839
Biological Process	GO:0002068	glandular epithelial cell development	Rarb	IGI	MGI:MGI:97858	Mouse	PMID:7607067
Biological Process	GO:0003417	growth plate cartilage development	Rarb	IGI	MGI:MGI:97858	Mouse	PMID:19389355
Biological Process	GO:0035264	multicellular organism growth	Rarb	IGI	MGI:MGI:97858	Mouse	PMID:19389355
Biological Process	GO:0061037	negative regulation of cartilage development	Rarb	IMP		Mouse	PMID:10684250
Biological Process	GO:0032331	negative regulation of chondrocyte differentiation	Rarb	IMP		Mouse	PMID:10684250
Biological Process	GO:2000647	negative regulation of stem cell proliferation	Rarb	IGI	MGI:MGI:97858	Mouse	PMID:10075839
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Rarb	IDA		Mouse	PMID:8152920
Biological Process	GO:0061351	neural precursor cell proliferation	Rarb	IDA		Rat	PMID:19100254|RGD:2314252
Biological Process	GO:0022008	neurogenesis	Rarb	IMP	MGI:MGI:1857851	Mouse	PMID:18443282
Biological Process	GO:0043065	positive regulation of apoptotic process	Rarb	IGI	MGI:MGI:97858	Mouse	PMID:16207763
Biological Process	GO:0043068	positive regulation of programmed cell death	Rarb	IGI	MGI:MGI:97858	Mouse	PMID:10075839
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Rarb	IGI	MGI:MGI:98215	Mouse	PMID:7823919
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Rarb	IGI	MGI:MGI:98216	Mouse	PMID:7823919
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Rarb	IGI	MGI:MGI:88071	Mouse	PMID:15766748
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Rarb	IGI	MGI:MGI:106918	Mouse	PMID:15766748
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Rarb	IGI	MGI:MGI:98214	Mouse	PMID:7823919
Biological Process	GO:0012501	programmed cell death	Rarb	IGI	MGI:MGI:97858	Mouse	PMID:10075839
Biological Process	GO:0031641	regulation of myelination	Rarb	IDA		Rat	PMID:20648638|RGD:6771320
Biological Process	GO:0072089	stem cell proliferation	Rarb	IGI	MGI:MGI:97858	Mouse	PMID:10075839
Biological Process	GO:0021756	striatum development	Rarb	IMP	MGI:MGI:1857851	Mouse	PMID:18443282
Biological Process	GO:0001657	ureteric bud development	Rarb	IMP	MGI:MGI:1857623	Mouse	PMID:12195422
Biological Process	GO:0055012	ventricular cardiac muscle cell differentiation	Rarb	IMP	MGI:MGI:1857851	Mouse	PMID:9428411

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern