Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RASGRF1
  • Mouse genes Rasgrf1
  • Rat genes Rasgrf1
  • Zfish genes rasgrf1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rasgrf1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0035254	glutamate receptor binding	Rasgrf1	IPI	PR:Q01097	Mouse	PMID:16710293
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	RASGRF1	IMP		Human	PMID:27856453
Molecular Function	GO:0005515	protein binding	Rasgrf1	IPI	UniProtKB:P01112	Mouse	MGI:MGI:5921406|PMID:19141281
Molecular Function	GO:0005515	protein binding	Rasgrf1	IPI	UniProtKB:P01112	Mouse	MGI:MGI:5921428|PMID:18454158
Molecular Function	GO:0005515	protein binding	Rasgrf1	IPI	UniProtKB:P12023	Mouse	MGI:MGI:5498614|PMID:23719799
Molecular Function	GO:0005515	protein binding	Rasgrf1	IPI	UniProtKB:O70166	Mouse	MGI:MGI:3706230|PMID:17135267
Molecular Function	GO:0005515	protein binding	Rasgrf1	IPI	RGD:69413	Rat	PMID:10373510|RGD:10003124
Molecular Function	GO:0005515	protein binding	Rasgrf1	IPI	UniProtKB:Q00960	Rat	PMID:14622581|RGD:8554730
Molecular Function	GO:0005515	protein binding	Rasgrf1	IPI	UniProtKB:Q9JHU6	Rat	PMID:17135267|RGD:8554560
Molecular Function	GO:0005515	protein binding	Rasgrf1	IPI	UniProtKB:Q9R012	Rat	PMID:21382555|RGD:7241548
Molecular Function	GO:0030971	receptor tyrosine kinase binding	Rasgrf1	IPI	RGD:620144	Rat	PMID:10691301|RGD:10003117
Molecular Function	GO:0031267	small GTPase binding	Rasgrf1	IDA		Rat	PMID:15798216|RGD:10003119
Cellular Component	GO:0097440	apical dendrite	Rasgrf1	IDA		Rat	PMID:12538592|RGD:10003123
Cellular Component	GO:0016327	apicolateral plasma membrane	Rasgrf1	IDA		Rat	PMID:9232829|RGD:10003126
Cellular Component	GO:0016323	basolateral plasma membrane	Rasgrf1	IDA		Rat	PMID:9232829|RGD:10003126
Cellular Component	GO:0005737	cytoplasm	Rasgrf1	IDA		Rat	PMID:9232829|RGD:10003126
Cellular Component	GO:0005829	cytosol	Rasgrf1	IDA		Mouse	MGI:MGI:3706230|PMID:17135267
Cellular Component	GO:0030426	growth cone	Rasgrf1	IDA		Mouse	MGI:MGI:3706230|PMID:17135267
Cellular Component	GO:0043025	neuronal cell body	Rasgrf1	IDA		Rat	PMID:12538592|RGD:10003123
Biological Process	GO:0090630	activation of GTPase activity	Rasgrf1	IDA		Mouse	MGI:MGI:3706230|PMID:17135267
Biological Process	GO:0090630	activation of GTPase activity	Rasgrf1	IMP		Rat	PMID:1379346|RGD:10003125
Biological Process	GO:0071236	cellular response to antibiotic	Rasgrf1	IEP		Rat	PMID:19002579|RGD:10003129
Biological Process	GO:0032869	cellular response to insulin stimulus	Rasgrf1	IEP		Rat	PMID:19002579|RGD:10003129
Biological Process	GO:0031175	neuron projection development	Rasgrf1	IDA		Mouse	MGI:MGI:3706230|PMID:17135267
Biological Process	GO:0048146	positive regulation of fibroblast proliferation	Rasgrf1	IMP		Rat	PMID:15798216|RGD:10003119
Biological Process	GO:0043547	positive regulation of GTPase activity	Rasgrf1	IDA		Mouse	MGI:MGI:3706230|PMID:17135267
Biological Process	GO:0043547	positive regulation of GTPase activity	Rasgrf1	IMP		Rat	PMID:15798216|RGD:10003119
Biological Process	GO:0046579	positive regulation of Ras protein signal transduction	Rasgrf1	IDA		Rat	PMID:21382555|RGD:7241548
Biological Process	GO:0048168	regulation of neuronal synaptic plasticity	Rasgrf1	IMP	MGI:MGI:2157015	Mouse	PMID:11749043
Biological Process	GO:2000310	regulation of NMDA receptor activity	Rasgrf1	IGI	MGI:MGI:109137	Mouse	PMID:15029245
Biological Process	GO:0035020	regulation of Rac protein signal transduction	Rasgrf1	IDA		Mouse	MGI:MGI:3706230|PMID:17135267
Biological Process	GO:0046578	regulation of Ras protein signal transduction	Rasgrf1	IDA		Mouse	MGI:MGI:3706230|PMID:17135267
Biological Process	GO:0048167	regulation of synaptic plasticity	Rasgrf1	IDA		Rat	PMID:21382555|RGD:7241548
Biological Process	GO:0001975	response to amphetamine	Rasgrf1	IEP		Rat	PMID:19686726|RGD:10003122
Biological Process	GO:0034976	response to endoplasmic reticulum stress	RASGRF1	IMP		Human	PMID:27856453
Biological Process	GO:0044342	type B pancreatic cell proliferation	Rasgrf1	IMP	MGI:MGI:2667231	Mouse	PMID:12805218

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern