Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RASGRF2
  • Mouse genes Rasgrf2
  • Rat genes Rasgrf2
  • Zfish genes rasgrf2a,rasgrf2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rasgrf2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	RASGRF2	IMP		Human	PMID:27856453
Molecular Function	GO:0005515	protein binding	Rasgrf2	IPI	RGD:620395	Rat	PMID:10373510|RGD:10003124
Cellular Component	GO:0005783	endoplasmic reticulum	RASGRF2	IDA		Human	GO_REF:0000052
Biological Process	GO:0060291	long-term synaptic potentiation	Rasgrf2	IGI	MGI:MGI:95820	Mouse	PMID:20661302
Biological Process	GO:2000310	regulation of NMDA receptor activity	Rasgrf2	IGI	MGI:MGI:99694	Mouse	PMID:15029245
Biological Process	GO:0034976	response to endoplasmic reticulum stress	RASGRF2	IMP		Human	PMID:27856453

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern