Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RASSF2
  • Mouse genes Rassf2
  • Rat genes Rassf2
  • Zfish genes rassf2a,rassf2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rassf2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	RASSF2	IPI	UniProtKB:P01116	Human	PMID:12732644
Molecular Function	GO:0005515	protein binding	RASSF2	IPI	UniProtKB:Q13043	Human	PMID:19525978
Molecular Function	GO:0005515	protein binding	RASSF2	IPI	UniProtKB:Q13188	Human	PMID:19525978
Molecular Function	GO:0005515	protein binding	RASSF2	IPI	UniProtKB:Q13043	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	RASSF2	IPI	UniProtKB:Q13043	Human	PMID:20920251
Molecular Function	GO:0005515	protein binding	RASSF2	IPI	UniProtKB:Q13188	Human	PMID:20920251
Molecular Function	GO:0005515	protein binding	RASSF2	IPI	UniProtKB:Q13043	Human	PMID:23386615
Molecular Function	GO:0005515	protein binding	RASSF2	IPI	UniProtKB:Q13043	Human	PMID:23455922
Molecular Function	GO:0005515	protein binding	RASSF2	IPI	UniProtKB:Q13188	Human	PMID:23455922
Molecular Function	GO:0005515	protein binding	RASSF2	IPI	UniProtKB:O43463	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	RASSF2	IPI	UniProtKB:O60341	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	RASSF2	IPI	UniProtKB:Q96LA8	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	RASSF2	IPI	UniProtKB:Q13043	Human	PMID:24255178
Molecular Function	GO:0005515	protein binding	RASSF2	IPI	UniProtKB:Q13188	Human	PMID:24255178
Molecular Function	GO:0005515	protein binding	RASSF2	IPI	UniProtKB:Q13043	Human	PMID:24366813
Molecular Function	GO:0005515	protein binding	RASSF2	IPI	UniProtKB:Q13188	Human	PMID:24366813
Molecular Function	GO:0005515	protein binding	RASSF2	IPI	UniProtKB:Q13043	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	RASSF2	IPI	UniProtKB:Q13188	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	RASSF2	IPI	UniProtKB:Q13188	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RASSF2	IPI	UniProtKB:Q8WWW0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RASSF2	IPI	UniProtKB:Q13188	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	RASSF2	IPI	UniProtKB:Q13188	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RASSF2	IPI	UniProtKB:Q8WXG8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RASSF2	IPI	UniProtKB:Q13188	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	RASSF2	IPI	UniProtKB:P14136	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	RASSF2	IPI	UniProtKB:P27797	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	RASSF2	IPI	UniProtKB:P36957	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	RASSF2	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	RASSF2	IPI	UniProtKB:Q8TDX7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	RASSF2	IPI	UniProtKB:Q8WXH2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	RASSF2	IPI	UniProtKB:Q96CV9	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Rassf2	IPI	PR:Q60680	Mouse	PMID:22227519
Molecular Function	GO:0005515	protein binding	Rassf2	IPI	PR:O88351	Mouse	PMID:22227519
Molecular Function	GO:0004672	protein kinase activity	RASSF2	IGI	UniProtKB:Q13043	Human	PMID:19962960
Cellular Component	GO:0005737	cytoplasm	RASSF2	IDA		Human	PMID:19525978
Cellular Component	GO:0005737	cytoplasm	Rassf2	IDA		Mouse	PMID:22227519
Cellular Component	GO:0005829	cytosol	RASSF2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005794	Golgi apparatus	RASSF2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0000776	kinetochore	RASSF2	IDA		Human	PMID:20813266
Cellular Component	GO:0005654	nucleoplasm	RASSF2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	RASSF2	IDA		Human	PMID:19525978
Cellular Component	GO:0005634	nucleus	Rassf2	IDA		Mouse	PMID:22227519
Cellular Component	GO:0005886	plasma membrane	RASSF2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0032991	protein-containing complex	RASSF2	IDA		Human	PMID:19962960
Biological Process	GO:0046849	bone remodeling	Rassf2	IMP	MGI:MGI:5314787	Mouse	PMID:22227519
Biological Process	GO:0038168	epidermal growth factor receptor signaling pathway via I-kappaB kinase/NF-kappaB cascade	Rassf2	IMP	MGI:MGI:5314787	Mouse	PMID:22227519
Biological Process	GO:0048872	homeostasis of number of cells	Rassf2	IMP	MGI:MGI:5314787	Mouse	PMID:22227519
Biological Process	GO:1901223	negative regulation of NIK/NF-kappaB signaling	Rassf2	IMP		Mouse	PMID:22227519
Biological Process	GO:0033137	negative regulation of peptidyl-serine phosphorylation	RASSF2	IDA		Human	PMID:19962960
Biological Process	GO:0001503	ossification	Rassf2	IMP	MGI:MGI:5314787	Mouse	PMID:22227519
Biological Process	GO:0043065	positive regulation of apoptotic process	RASSF2	IDA		Human	PMID:19962960
Biological Process	GO:0046330	positive regulation of JNK cascade	RASSF2	IDA		Human	PMID:19962960
Biological Process	GO:0031954	positive regulation of protein autophosphorylation	RASSF2	IDA		Human	PMID:19962960
Biological Process	GO:0045860	positive regulation of protein kinase activity	RASSF2	IDA		Human	PMID:19962960
Biological Process	GO:0050821	protein stabilization	RASSF2	IMP		Human	PMID:19525978
Biological Process	GO:1901222	regulation of NIK/NF-kappaB signaling	Rassf2	IMP	MGI:MGI:5314787	Mouse	PMID:22227519
Biological Process	GO:0045667	regulation of osteoblast differentiation	Rassf2	IMP	MGI:MGI:5314787	Mouse	PMID:22227519
Biological Process	GO:0045670	regulation of osteoclast differentiation	Rassf2	IMP	MGI:MGI:5314787	Mouse	PMID:22227519
Biological Process	GO:0001501	skeletal system development	Rassf2	IMP	MGI:MGI:5314787	Mouse	PMID:22227519

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern