Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RAX
  • Mouse genes Rax
  • Rat genes Rax
  • Zfish genes rx1,rx2,rx3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rax

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	RAX	IDA		Human	PMID:10625658
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	RAX	IDA		Human	PMID:10625658
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	RAX	IDA		Human	PMID:28473536
Biological Process	GO:0021984	adenohypophysis development	rx3	IMP	ZFIN:ZDB-GENO-051229-1	Zfish	PMID:17373855
Biological Process	GO:0007420	brain development	Rax	IMP	MGI:MGI:2152531	Mouse	PMID:15789424
Biological Process	GO:0043010	camera-type eye development	Rax	IMP	MGI:MGI:2152531	Mouse	PMID:11105055
Biological Process	GO:0043010	camera-type eye development	Rax	IMP	MGI:MGI:1856862	Mouse	PMID:17247120
Biological Process	GO:0043010	camera-type eye development	Rax	IMP	MGI:MGI:2152531	Mouse	PMID:15789424
Biological Process	GO:0043010	camera-type eye development	Rax	IMP	MGI:MGI:1856862	Mouse	PMID:640224
Biological Process	GO:0043010	camera-type eye development	Rax	IMP	MGI:MGI:1856862	Mouse	PMID:13970081
Biological Process	GO:0048593	camera-type eye morphogenesis	rx3	IMP	ZFIN:ZDB-GENO-081016-1	Zfish	PMID:12947416
Biological Process	GO:0060219	camera-type eye photoreceptor cell differentiation	rx1	IGI	ZFIN:ZDB-MRPHLNO-060109-2,ZFIN:ZDB-MRPHLNO-060109-4,ZFIN:ZDB-MRPHLNO-100423-2,ZFIN:ZDB-MRPHLNO-100423-3	Zfish	PMID:19210961
Biological Process	GO:0060219	camera-type eye photoreceptor cell differentiation	rx1	IMP	ZFIN:ZDB-MRPHLNO-060109-2,ZFIN:ZDB-MRPHLNO-100423-2	Zfish	PMID:19210961
Biological Process	GO:0060219	camera-type eye photoreceptor cell differentiation	rx2	IGI	ZFIN:ZDB-MRPHLNO-060109-2,ZFIN:ZDB-MRPHLNO-060109-4,ZFIN:ZDB-MRPHLNO-100423-2,ZFIN:ZDB-MRPHLNO-100423-3	Zfish	PMID:19210961
Biological Process	GO:0001708	cell fate specification	rx3	IMP	ZFIN:ZDB-GENO-051229-2	Zfish	PMID:16300752
Biological Process	GO:0001708	cell fate specification	rx3	IMP	ZFIN:ZDB-GENO-051229-1	Zfish	PMID:16300752
Biological Process	GO:0048596	embryonic camera-type eye morphogenesis	rx3	IMP	ZFIN:ZDB-GENO-051229-2	Zfish	PMID:16300752
Biological Process	GO:0048596	embryonic camera-type eye morphogenesis	rx3	IMP	ZFIN:ZDB-MRPHLNO-060109-5	Zfish	PMID:16300752
Biological Process	GO:0048596	embryonic camera-type eye morphogenesis	rx3	IMP	ZFIN:ZDB-GENO-051229-1	Zfish	PMID:16300752
Biological Process	GO:0048596	embryonic camera-type eye morphogenesis	rx3	IMP	ZFIN:ZDB-GENO-060822-1	Zfish	PMID:16818451
Biological Process	GO:0048596	embryonic camera-type eye morphogenesis	rx3	IMP	ZFIN:ZDB-MRPHLNO-060109-6	Zfish	PMID:16300752
Biological Process	GO:0001654	eye development	rx3	IMP	ZFIN:ZDB-GENO-040513-1	Zfish	PMID:15183718
Biological Process	GO:0060898	eye field cell fate commitment involved in camera-type eye formation	rx3	IMP	ZFIN:ZDB-GENO-131219-2	Zfish	PMID:24026122
Biological Process	GO:0060898	eye field cell fate commitment involved in camera-type eye formation	rx3	IMP	ZFIN:ZDB-GENO-150212-4	Zfish	PMID:24026122
Biological Process	GO:0030900	forebrain development	rx3	IMP	ZFIN:ZDB-GENO-060822-1	Zfish	PMID:16818451
Biological Process	GO:0021854	hypothalamus development	Rax	IMP	MGI:MGI:1856862	Mouse	PMID:925203
Biological Process	GO:0021854	hypothalamus development	rx3	IMP	ZFIN:ZDB-GENO-150206-3	Zfish	PMID:27317806
Biological Process	GO:0060173	limb development	Rax	IMP	MGI:MGI:1856862	Mouse	PMID:13970082
Biological Process	GO:0001755	neural crest cell migration	rx3	IMP	ZFIN:ZDB-GENO-081016-1	Zfish	PMID:18498099
Biological Process	GO:0003407	neural retina development	rx1	IMP	ZFIN:ZDB-MRPHLNO-060109-2,ZFIN:ZDB-MRPHLNO-100423-2	Zfish	PMID:19210961
Biological Process	GO:0007389	pattern specification process	Rax	IMP	MGI:MGI:1856862	Mouse	PMID:13970082
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	RAX	IDA		Human	PMID:10625658
Biological Process	GO:0060041	retina development in camera-type eye	rx3	IMP	ZFIN:ZDB-GENO-081016-1	Zfish	PMID:12947416
Biological Process	GO:0010842	retina layer formation	rx1	IMP	ZFIN:ZDB-MRPHLNO-060109-2,ZFIN:ZDB-MRPHLNO-100423-2	Zfish	PMID:19210961

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern