Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RB1CC1
  • Mouse genes Rb1cc1
  • Rat genes Rb1cc1
  • Zfish genes rb1cc1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rb1cc1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	RB1CC1	IPI	UniProtKB:O75143	Human	PMID:19211835
Molecular Function	GO:0005515	protein binding	RB1CC1	IPI	UniProtKB:O75385	Human	PMID:19211835
Molecular Function	GO:0005515	protein binding	RB1CC1	IPI	UniProtKB:O75143	Human	PMID:19597335
Molecular Function	GO:0005515	protein binding	RB1CC1	IPI	UniProtKB:Q9BSB4	Human	PMID:19597335
Molecular Function	GO:0005515	protein binding	RB1CC1	IPI	UniProtKB:O75143	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	RB1CC1	IPI	UniProtKB:O75385	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	RB1CC1	IPI	UniProtKB:Q676U5	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	RB1CC1	IPI	UniProtKB:Q9BSB4	Human	PMID:20562859
Molecular Function	GO:0005515	protein binding	RB1CC1	IPI	UniProtKB:A7MCY6	Human	PMID:21903422
Molecular Function	GO:0005515	protein binding	RB1CC1	IPI	UniProtKB:Q676U5	Human	PMID:23262492
Molecular Function	GO:0005515	protein binding	RB1CC1	IPI	UniProtKB:Q8C0J2-3	Human	PMID:23262492
Molecular Function	GO:0005515	protein binding	RB1CC1	IPI	UniProtKB:Q9H1Y0	Human	PMID:23262492
Molecular Function	GO:0005515	protein binding	RB1CC1	IPI	UniProtKB:O75143	Human	PMID:23392225
Molecular Function	GO:0005515	protein binding	RB1CC1	IPI	UniProtKB:O75385	Human	PMID:23392225
Molecular Function	GO:0005515	protein binding	RB1CC1	IPI	UniProtKB:Q676U5	Human	PMID:23392225
Molecular Function	GO:0005515	protein binding	RB1CC1	IPI	UniProtKB:Q9BSB4	Human	PMID:23392225
Molecular Function	GO:0005515	protein binding	RB1CC1	IPI	UniProtKB:Q9H1Y0	Human	PMID:23392225
Molecular Function	GO:0005515	protein binding	RB1CC1	IPI	UniProtKB:O75385	Human	PMID:23524951
Molecular Function	GO:0005515	protein binding	RB1CC1	IPI	UniProtKB:O75385	Human	PMID:25686248
Molecular Function	GO:0005515	protein binding	RB1CC1	IPI	UniProtKB:Q96LT7-1	Human	PMID:27334615
Molecular Function	GO:0005515	protein binding	RB1CC1	IPI	UniProtKB:Q96LT7-2	Human	PMID:27334615
Molecular Function	GO:0005515	protein binding	RB1CC1	IPI	UniProtKB:Q5MNZ6	Human	PMID:28561066
Molecular Function	GO:0005515	protein binding	RB1CC1	IPI	UniProtKB:O75385,UniProtKB:Q9Y4P8	Human	PMID:28890335
Molecular Function	GO:0005515	protein binding	RB1CC1	IPI	UniProtKB:Q676U5|UniProtKB:Q9Y4P8	Human	PMID:28890335
Molecular Function	GO:0005515	protein binding	RB1CC1	IPI	UniProtKB:Q96LT7-1	Human	PMID:29950492
Molecular Function	GO:0005515	protein binding	RB1CC1	IPI	UniProtKB:O75143	Human	PMID:31806350
Molecular Function	GO:0005515	protein binding	RB1CC1	IPI	UniProtKB:O75385	Human	PMID:32707033
Molecular Function	GO:0005515	protein binding	RB1CC1	IPI	UniProtKB:O75143	Human	PMID:33368531
Molecular Function	GO:0005515	protein binding	RB1CC1	IPI	UniProtKB:O75385	Human	PMID:33422265
Molecular Function	GO:0005515	protein binding	Rb1cc1	IPI	UniProtKB:Q8C0J2-3|UniProtKB:Q8C0J2	Mouse	MGI:MGI:5916255|PMID:23262492
Molecular Function	GO:0005515	protein binding	Rb1cc1	IPI	UniProtKB:O70405|UniProtKB:Q91YI1	Mouse	MGI:MGI:3849242|PMID:19258318
Molecular Function	GO:0005515	protein binding	Rb1cc1	IPI	UniProtKB:Q5MNZ6	Mouse	MGI:MGI:5920682|PMID:28561066
Molecular Function	GO:0005515	protein binding	Rb1cc1	IPI	UniProtKB:Q8C0J2	Mouse	MGI:MGI:5508687|PMID:23392225
Molecular Function	GO:0005515	protein binding	Rb1cc1	IPI	PR:Q8C0J2	Mouse	PMID:24954904
Molecular Function	GO:0019901	protein kinase binding	RB1CC1	IDA		Human	PMID:19211835
Molecular Function	GO:0019901	protein kinase binding	Rb1cc1	IPI	UniProtKB:O70405|UniProtKB:Q9QY01	Mouse	MGI:MGI:3796758|PMID:18443221
Cellular Component	GO:1990316	Atg1/ULK1 kinase complex	RB1CC1	IPI		Human	PMID:19597335
Cellular Component	GO:1990316	Atg1/ULK1 kinase complex	RB1CC1	IPI	UniProtKB:Q8TDY2	Human	PMID:19211835
Cellular Component	GO:1990316	Atg1/ULK1 kinase complex	Rb1cc1	IPI	UniProtKB:O70405|UniProtKB:Q91YI1	Mouse	MGI:MGI:3849242|PMID:19258318
Cellular Component	GO:1990316	Atg1/ULK1 kinase complex	Rb1cc1	IDA		Mouse	PMID:19211835
Cellular Component	GO:0000421	autophagosome membrane	Rb1cc1	IDA		Mouse	PMID:31006538
Cellular Component	GO:0005829	cytosol	RB1CC1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005764	lysosome	RB1CC1	IDA		Human	PMID:28561066
Cellular Component	GO:0031965	nuclear membrane	RB1CC1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Rb1cc1	IDA		Mouse	PMID:12095676
Cellular Component	GO:0000407	phagophore assembly site	RB1CC1	IDA		Human	PMID:19597335
Cellular Component	GO:0000407	phagophore assembly site	RB1CC1	IDA		Human	PMID:28561066
Cellular Component	GO:0000407	phagophore assembly site	Rb1cc1	IDA		Mouse	MGI:MGI:3849242|PMID:19258318
Cellular Component	GO:0000407	phagophore assembly site	Rb1cc1	IDA		Mouse	MGI:MGI:6810790|PMID:18936157
Cellular Component	GO:0034045	phagophore assembly site membrane	Rb1cc1	IDA		Mouse	MGI:MGI:3796758|PMID:18443221
Biological Process	GO:0006915	apoptotic process	Rb1cc1	IMP	MGI:MGI:3690329	Mouse	PMID:17015619
Biological Process	GO:0000045	autophagosome assembly	RB1CC1	IDA		Human	PMID:19225151
Biological Process	GO:0000045	autophagosome assembly	RB1CC1	IDA		Human	PMID:28890335
Biological Process	GO:0000045	autophagosome assembly	Rb1cc1	IMP		Mouse	MGI:MGI:3849242|PMID:19258318
Biological Process	GO:0000045	autophagosome assembly	Rb1cc1	IDA		Mouse	MGI:MGI:6810791|PMID:19225151
Biological Process	GO:0006914	autophagy	Rb1cc1	IMP		Mouse	MGI:MGI:3796758|PMID:18443221
Biological Process	GO:0006914	autophagy	Rb1cc1	IMP	MGI:3526069,MGI:2176173	Mouse	PMID:31006538
Biological Process	GO:0006914	autophagy	rb1cc1	IMP	ZFIN:ZDB-GENO-180214-2	Zfish	PMID:27818143
Biological Process	GO:0097191	extrinsic apoptotic signaling pathway	Rb1cc1	IMP	MGI:MGI:3690329	Mouse	PMID:17015619
Biological Process	GO:0007507	heart development	Rb1cc1	IMP	MGI:MGI:3690329	Mouse	PMID:17015619
Biological Process	GO:0001889	liver development	Rb1cc1	IMP	MGI:MGI:3690329	Mouse	PMID:17015619
Biological Process	GO:0043066	negative regulation of apoptotic process	Rb1cc1	IMP	MGI:MGI:3690329	Mouse	PMID:17015619
Biological Process	GO:0008285	negative regulation of cell population proliferation	RB1CC1	IDA		Human	PMID:21795849
Biological Process	GO:0008285	negative regulation of cell population proliferation	Rb1cc1	IDA		Mouse	MGI:MGI:6810792|PMID:21795849
Biological Process	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway	Rb1cc1	IMP	MGI:MGI:3690329	Mouse	PMID:17015619
Biological Process	GO:0010508	positive regulation of autophagy	Rb1cc1	IDA		Mouse	MGI:MGI:6810791|PMID:19225151
Biological Process	GO:0045793	positive regulation of cell size	Rb1cc1	IMP	MGI:MGI:3690329	Mouse	PMID:17015619
Biological Process	GO:0046330	positive regulation of JNK cascade	Rb1cc1	IGI	MGI:MGI:104798	Mouse	PMID:17015619
Biological Process	GO:0001934	positive regulation of protein phosphorylation	Rb1cc1	IMP	MGI:MGI:3690329	Mouse	PMID:17015619
Biological Process	GO:0046777	protein autophosphorylation	RB1CC1	IDA		Human	PMID:19225151
Biological Process	GO:0046777	protein autophosphorylation	Rb1cc1	IDA		Mouse	MGI:MGI:5285135|PMID:21258367
Biological Process	GO:0006468	protein phosphorylation	RB1CC1	IDA		Human	PMID:19225151
Biological Process	GO:0006468	protein phosphorylation	Rb1cc1	IDA		Mouse	MGI:MGI:6810791|PMID:19225151
Biological Process	GO:0006468	protein phosphorylation	Rb1cc1	IMP	MGI:MGI:3690329	Mouse	PMID:17015619
Biological Process	GO:1903059	regulation of protein lipidation	RB1CC1	IDA		Human	PMID:19225151
Biological Process	GO:1903059	regulation of protein lipidation	Rb1cc1	IDA		Mouse	MGI:MGI:6810791|PMID:19225151
Biological Process	GO:0061709	reticulophagy	Rb1cc1	IMP	MGI:3526069,MGI:2176173	Mouse	PMID:31006538

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern