Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RBCK1
  • Mouse genes Rbck1
  • Rat genes Rbck1
  • Zfish genes rbck1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rbck1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003690	double-stranded DNA binding	Rbck1	IDA		Rat	PMID:9514928|RGD:1299423
Molecular Function	GO:0042802	identical protein binding	RBCK1	IPI	UniProtKB:Q9BYM8	Human	PMID:25416956
Molecular Function	GO:0042802	identical protein binding	RBCK1	IPI	UniProtKB:Q9BYM8	Human	PMID:30561431
Molecular Function	GO:0005515	protein binding	RBCK1	IPI	UniProtKB:Q9JLY0	Human	PMID:16643902
Molecular Function	GO:0005515	protein binding	RBCK1	IPI	UniProtKB:Q96EP0	Human	PMID:17006537
Molecular Function	GO:0005515	protein binding	RBCK1	IPI	UniProtKB:O43318	Human	PMID:17449468
Molecular Function	GO:0005515	protein binding	RBCK1	IPI	UniProtKB:Q13546	Human	PMID:17449468
Molecular Function	GO:0005515	protein binding	RBCK1	IPI	UniProtKB:Q8N5C8	Human	PMID:17449468
Molecular Function	GO:0005515	protein binding	RBCK1	IPI	UniProtKB:Q9NYJ8	Human	PMID:17449468
Molecular Function	GO:0005515	protein binding	RBCK1	IPI	UniProtKB:Q9Y4K3	Human	PMID:17449468
Molecular Function	GO:0005515	protein binding	RBCK1	IPI	UniProtKB:Q14653	Human	PMID:18711448
Molecular Function	GO:0005515	protein binding	RBCK1	IPI	UniProtKB:O14933	Human	PMID:19549727
Molecular Function	GO:0005515	protein binding	RBCK1	IPI	UniProtKB:P61088	Human	PMID:19549727
Molecular Function	GO:0005515	protein binding	RBCK1	IPI	UniProtKB:P68036	Human	PMID:19549727
Molecular Function	GO:0005515	protein binding	RBCK1	IPI	UniProtKB:Q9Y6K9	Human	PMID:20098747
Molecular Function	GO:0005515	protein binding	RBCK1	IPI	UniProtKB:Q96EP0	Human	PMID:21455180
Molecular Function	GO:0005515	protein binding	RBCK1	IPI	UniProtKB:Q9H0F6	Human	PMID:21455180
Molecular Function	GO:0005515	protein binding	RBCK1	IPI	UniProtKB:Q9Y6K9	Human	PMID:21455180
Molecular Function	GO:0005515	protein binding	RBCK1	IPI	UniProtKB:Q96EP0	Human	PMID:21455181
Molecular Function	GO:0005515	protein binding	RBCK1	IPI	UniProtKB:Q9H0F6	Human	PMID:21455181
Molecular Function	GO:0005515	protein binding	RBCK1	IPI	UniProtKB:Q9Y6K9	Human	PMID:21709223
Molecular Function	GO:0005515	protein binding	RBCK1	IPI	UniProtKB:Q9Y6K9	Human	PMID:21811235
Molecular Function	GO:0005515	protein binding	RBCK1	IPI	UniProtKB:Q4VA12	Human	PMID:21903422
Molecular Function	GO:0005515	protein binding	RBCK1	IPI	UniProtKB:Q96EP0	Human	PMID:22430200
Molecular Function	GO:0005515	protein binding	RBCK1	IPI	UniProtKB:Q96EP0	Human	PMID:22791023
Molecular Function	GO:0005515	protein binding	RBCK1	IPI	UniProtKB:Q9H0F6	Human	PMID:23032186
Molecular Function	GO:0005515	protein binding	RBCK1	IPI	UniProtKB:Q9Y6K9	Human	PMID:23032186
Molecular Function	GO:0005515	protein binding	RBCK1	IPI	UniProtKB:P09022	Human	PMID:23088713
Molecular Function	GO:0005515	protein binding	RBCK1	IPI	UniProtKB:Q96EP0	Human	PMID:24141947
Molecular Function	GO:0005515	protein binding	RBCK1	IPI	UniProtKB:P61088	Human	PMID:25260751
Molecular Function	GO:0005515	protein binding	RBCK1	IPI	UniProtKB:O14933	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RBCK1	IPI	UniProtKB:P41227	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RBCK1	IPI	UniProtKB:Q8N0S2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RBCK1	IPI	UniProtKB:Q96PN8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RBCK1	IPI	UniProtKB:Q9BU61	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RBCK1	IPI	UniProtKB:Q9BU61-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RBCK1	IPI	UniProtKB:A0A0S2Z4Q4	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	RBCK1	IPI	UniProtKB:Q96EP0	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	RBCK1	IPI	UniProtKB:Q96EP0	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	RBCK1	IPI	UniProtKB:Q96EP0	Human	PMID:29997244
Molecular Function	GO:0005515	protein binding	RBCK1	IPI	UniProtKB:Q96EP0	Human	PMID:30561431
Molecular Function	GO:0005515	protein binding	RBCK1	IPI	UniProtKB:Q9H0F6	Human	PMID:30561431
Molecular Function	GO:0005515	protein binding	RBCK1	IPI	UniProtKB:O14933	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RBCK1	IPI	UniProtKB:O60336	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RBCK1	IPI	UniProtKB:P25786	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RBCK1	IPI	UniProtKB:P31273	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RBCK1	IPI	UniProtKB:P68036	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RBCK1	IPI	UniProtKB:Q02930-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RBCK1	IPI	UniProtKB:Q14005-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RBCK1	IPI	UniProtKB:Q5W5X9-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RBCK1	IPI	UniProtKB:Q63ZY3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RBCK1	IPI	UniProtKB:Q8IVS8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RBCK1	IPI	UniProtKB:Q8TBB1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RBCK1	IPI	UniProtKB:Q96IQ9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RBCK1	IPI	UniProtKB:Q96PN8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RBCK1	IPI	UniProtKB:Q9H0I2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RBCK1	IPI	UniProtKB:P54253	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	RBCK1	IPI	UniProtKB:P61086	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	RBCK1	IPI	UniProtKB:Q13148	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	RBCK1	IPI	UniProtKB:Q96EP0	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Rbck1	IPI	UniProtKB:Q924T7	Mouse	MGI:MGI:5516129|PMID:23942237
Molecular Function	GO:0005515	protein binding	Rbck1	IPI	UniProtKB:Q924T7	Mouse	MGI:MGI:4947438|PMID:21455180
Molecular Function	GO:0005515	protein binding	Rbck1	IPI	UniProtKB:P97767	Mouse	MGI:MGI:5437425|PMID:20956555
Molecular Function	GO:0005515	protein binding	Rbck1	IPI	UniProtKB:Q924T7	Mouse	MGI:MGI:4946301|PMID:21455181
Molecular Function	GO:0005515	protein binding	Rbck1	IPI	UniProtKB:P0CG48	Rat	PMID:19796170|RGD:8554763
Molecular Function	GO:0005515	protein binding	Rbck1	IPI	UniProtKB:P55036	Rat	PMID:19796170|RGD:8554763
Molecular Function	GO:0005080	protein kinase C binding	Rbck1	IPI	RGD:3395	Rat	PMID:9514928|RGD:1299423
Molecular Function	GO:0005080	protein kinase C binding	Rbck1	IPI	RGD:3397	Rat	PMID:9514928|RGD:1299423
Molecular Function	GO:0005080	protein kinase C binding	Rbck1	IPI	RGD:3399	Rat	PMID:9514928|RGD:1299423
Molecular Function	GO:0005080	protein kinase C binding	Rbck1	IPI	RGD:61925	Rat	PMID:9514928|RGD:1299423
Molecular Function	GO:0005080	protein kinase C binding	Rbck1	IPI	RGD:67383	Rat	PMID:9514928|RGD:1299423
Molecular Function	GO:0043130	ubiquitin binding	RBCK1	IDA		Human	PMID:21455181
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	RBCK1	IDA		Human	PMID:12629548
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	RBCK1	IDA		Human	PMID:17006537
Cellular Component	GO:0071797	LUBAC complex	RBCK1	IPI		Human	PMID:21455180
Cellular Component	GO:0071797	LUBAC complex	RBCK1	IDA		Human	PMID:17006537
Cellular Component	GO:0071797	LUBAC complex	RBCK1	IDA		Human	PMID:21455173
Cellular Component	GO:0071797	LUBAC complex	RBCK1	IDA		Human	PMID:21455180
Cellular Component	GO:0071797	LUBAC complex	RBCK1	IDA		Human	PMID:21455181
Cellular Component	GO:0071797	LUBAC complex	RBCK1	IDA		Human	PMID:24726323
Cellular Component	GO:0071797	LUBAC complex	RBCK1	IDA		Human	PMID:27523608
Cellular Component	GO:0071797	LUBAC complex	RBCK1	IDA		Human	PMID:28481331
Biological Process	GO:0042742	defense response to bacterium	RBCK1	IMP		Human	PMID:28481331
Biological Process	GO:0048701	embryonic cranial skeleton morphogenesis	rbck1	IMP	ZFIN:ZDB-MRPHLNO-101207-10	Zfish	PMID:20956555
Biological Process	GO:0060546	negative regulation of necroptotic process	Rbck1	IGI	MGI:MGI:104798	Mouse	PMID:22089168
Biological Process	GO:0032088	negative regulation of NF-kappaB transcription factor activity	RBCK1	IDA		Human	PMID:17449468
Biological Process	GO:0043065	positive regulation of apoptotic process	Rbck1	IMP		Mouse	MGI:MGI:4437982|PMID:19136968
Biological Process	GO:2001238	positive regulation of extrinsic apoptotic signaling pathway	Rbck1	IMP	MGI:MGI:5000222	Mouse	PMID:19136968
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	RBCK1	IDA		Human	PMID:19136968
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	RBCK1	IDA		Human	PMID:21455173
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	Rbck1	IMP		Mouse	MGI:MGI:4437982|PMID:19136968
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	RBCK1	IDA		Human	PMID:19136968
Biological Process	GO:1901224	positive regulation of NIK/NF-kappaB signaling	Rbck1	IMP		Mouse	MGI:MGI:4437982|PMID:19136968
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Rbck1	IDA		Rat	PMID:9514928|RGD:1299423
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	RBCK1	IMP		Human	PMID:17449468
Biological Process	GO:0097039	protein linear polyubiquitination	RBCK1	IDA		Human	PMID:21455173
Biological Process	GO:0097039	protein linear polyubiquitination	RBCK1	IDA		Human	PMID:21455180
Biological Process	GO:0097039	protein linear polyubiquitination	RBCK1	IDA		Human	PMID:21455181
Biological Process	GO:0097039	protein linear polyubiquitination	RBCK1	IDA		Human	PMID:23453807
Biological Process	GO:0097039	protein linear polyubiquitination	RBCK1	IDA		Human	PMID:29694895
Biological Process	GO:0000209	protein polyubiquitination	RBCK1	IDA		Human	PMID:12629548
Biological Process	GO:0000209	protein polyubiquitination	RBCK1	IDA		Human	PMID:17006537
Biological Process	GO:0050852	T cell receptor signaling pathway	RBCK1	IDA		Human	PMID:20005846

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern