Comparative GO Graph (mouse, human, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RBM4
  • Mouse genes Rbm4
  • Rat genes
  • Zfish genes rbm4.1,rbm4.2,rbm4.3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rbm4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0030332	cyclin binding	RBM4	IPI	UniProtKB:P78396	Human	PMID:15159402
Molecular Function	GO:0035198	miRNA binding	RBM4	IDA		Human	PMID:19801630
Molecular Function	GO:0003730	mRNA 3'-UTR binding	Rbm4	IDA		Mouse	PMID:17264215
Molecular Function	GO:0003730	mRNA 3'-UTR binding	rbm4.2	IDA		Zfish	PMID:31227602
Molecular Function	GO:0003729	mRNA binding	RBM4	IDA		Human	PMID:21518792
Molecular Function	GO:0036002	pre-mRNA binding	Rbm4	IDA		Mouse	MGI:MGI:5447617|PMID:16260624
Molecular Function	GO:0097157	pre-mRNA intronic binding	RBM4	IDA		Human	PMID:16260624
Molecular Function	GO:0097158	pre-mRNA intronic pyrimidine-rich binding	RBM4	IDA		Human	PMID:16260624
Molecular Function	GO:0097158	pre-mRNA intronic pyrimidine-rich binding	RBM4	IDA		Human	PMID:16777844
Molecular Function	GO:0005515	protein binding	RBM4	IPI	UniProtKB:Q9Y5L0	Human	PMID:12628928
Molecular Function	GO:0005515	protein binding	RBM4	IPI	UniProtKB:P19544	Human	PMID:16934801
Molecular Function	GO:0005515	protein binding	RBM4	IPI	UniProtKB:P60842	Human	PMID:17284590
Molecular Function	GO:0005515	protein binding	RBM4	IPI	UniProtKB:Q04637	Human	PMID:17284590
Molecular Function	GO:0005515	protein binding	RBM4	IPI	UniProtKB:Q9UKV8	Human	PMID:19801630
Molecular Function	GO:0005515	protein binding	RBM4	IPI	UniProtKB:P17844	Human	PMID:21343338
Molecular Function	GO:0005515	protein binding	RBM4	IPI	UniProtKB:P02489	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	RBM4	IPI	UniProtKB:P22607	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	RBM4	IPI	UniProtKB:Q86V38	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	RBM4	IPI	UniProtKB:Q92876	Human	PMID:32814053
Molecular Function	GO:0003723	RNA binding	RBM4	IDA		Human	PMID:19561594
Molecular Function	GO:0003723	RNA binding	RBM4	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	RBM4	HDA		Human	PMID:22681889
Cellular Component	GO:0005737	cytoplasm	RBM4	IDA		Human	PMID:12628928
Cellular Component	GO:0005737	cytoplasm	RBM4	IDA		Human	PMID:16777844
Cellular Component	GO:0005737	cytoplasm	RBM4	IDA		Human	PMID:16907643
Cellular Component	GO:0005737	cytoplasm	RBM4	IDA		Human	PMID:17284590
Cellular Component	GO:0005737	cytoplasm	Rbm4	IDA		Mouse	MGI:MGI:4436983|PMID:19801630
Cellular Component	GO:0010494	cytoplasmic stress granule	RBM4	IDA		Human	PMID:17284590
Cellular Component	GO:0005829	cytosol	RBM4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016607	nuclear speck	RBM4	IDA		Human	PMID:12628928
Cellular Component	GO:0016607	nuclear speck	RBM4	IDA		Human	PMID:16907643
Cellular Component	GO:0005730	nucleolus	RBM4	IDA		Human	PMID:12628928
Cellular Component	GO:0005730	nucleolus	RBM4	IDA		Human	PMID:16907643
Cellular Component	GO:0005730	nucleolus	Rbm4	IDA		Mouse	MGI:MGI:4436983|PMID:19801630
Cellular Component	GO:0005654	nucleoplasm	RBM4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	RBM4	IDA		Human	PMID:12628928
Cellular Component	GO:0005634	nucleus	RBM4	IDA		Human	PMID:16777844
Cellular Component	GO:0005634	nucleus	RBM4	IDA		Human	PMID:16907643
Cellular Component	GO:0005634	nucleus	RBM4	IDA		Human	PMID:17284590
Cellular Component	GO:0005634	nucleus	Rbm4	IDA		Mouse	MGI:MGI:4436983|PMID:19801630
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Rbm4	IDA		Mouse	MGI:MGI:4436983|PMID:19801630
Biological Process	GO:0002190	cap-independent translational initiation	RBM4	IDA		Human	PMID:17284590
Biological Process	GO:0032922	circadian regulation of gene expression	Rbm4	IMP		Mouse	PMID:17264215
Biological Process	GO:0097167	circadian regulation of translation	Rbm4	IDA		Mouse	MGI:MGI:3703208|PMID:17264215
Biological Process	GO:0035883	enteroendocrine cell differentiation	Rbm4	IMP	MGI:MGI:5467987	Mouse	PMID:23129807
Biological Process	GO:0035883	enteroendocrine cell differentiation	Rbm4	IMP	MGI:MGI:5467988	Mouse	PMID:23129807
Biological Process	GO:0043153	entrainment of circadian clock by photoperiod	Rbm4	IDA		Mouse	MGI:MGI:3703208|PMID:17264215
Biological Process	GO:0042593	glucose homeostasis	Rbm4	IMP	MGI:MGI:5467987	Mouse	PMID:23129807
Biological Process	GO:0035773	insulin secretion involved in cellular response to glucose stimulus	Rbm4	IMP	MGI:MGI:5467988	Mouse	PMID:23129807
Biological Process	GO:0035773	insulin secretion involved in cellular response to glucose stimulus	Rbm4	IMP	MGI:MGI:5467987	Mouse	PMID:23129807
Biological Process	GO:0002192	IRES-dependent translational initiation of linear mRNA	RBM4	IDA		Human	PMID:17284590
Biological Process	GO:0035278	miRNA-mediated gene silencing by inhibition of translation	RBM4	IDA		Human	PMID:19801630
Biological Process	GO:0017148	negative regulation of translation	RBM4	IDA		Human	PMID:17284590
Biological Process	GO:0032055	negative regulation of translation in response to stress	RBM4	IDA		Human	PMID:17284590
Biological Process	GO:0045947	negative regulation of translational initiation	RBM4	IDA		Human	PMID:19801630
Biological Process	GO:0031016	pancreas development	Rbm4	IMP	MGI:MGI:5467987	Mouse	PMID:23129807
Biological Process	GO:0031016	pancreas development	Rbm4	IMP	MGI:MGI:5467988	Mouse	PMID:23129807
Biological Process	GO:0051149	positive regulation of muscle cell differentiation	RBM4	IDA		Human	PMID:21518792
Biological Process	GO:0045727	positive regulation of translation	Rbm4	IDA		Mouse	PMID:17264215
Biological Process	GO:0000381	regulation of alternative mRNA splicing, via spliceosome	RBM4	IDA		Human	PMID:12628928
Biological Process	GO:0000381	regulation of alternative mRNA splicing, via spliceosome	RBM4	IDA		Human	PMID:16260624
Biological Process	GO:0000381	regulation of alternative mRNA splicing, via spliceosome	RBM4	IDA		Human	PMID:16777844
Biological Process	GO:0000381	regulation of alternative mRNA splicing, via spliceosome	RBM4	IDA		Human	PMID:16934801
Biological Process	GO:0000381	regulation of alternative mRNA splicing, via spliceosome	RBM4	IDA		Human	PMID:21518792
Biological Process	GO:0000381	regulation of alternative mRNA splicing, via spliceosome	Rbm4	IMP	MGI:MGI:5467988	Mouse	PMID:23129807
Biological Process	GO:0000381	regulation of alternative mRNA splicing, via spliceosome	Rbm4	IMP	MGI:MGI:5467987	Mouse	PMID:23129807
Biological Process	GO:0010468	regulation of gene expression	Rbm4	IMP	MGI:MGI:5467988	Mouse	PMID:23129807
Biological Process	GO:0010468	regulation of gene expression	Rbm4	IMP	MGI:MGI:5467987	Mouse	PMID:23129807
Biological Process	GO:0046626	regulation of insulin receptor signaling pathway	Rbm4	IDA		Mouse	PMID:23129807
Biological Process	GO:0046822	regulation of nucleocytoplasmic transport	RBM4	IDA		Human	PMID:12628928
Biological Process	GO:0046822	regulation of nucleocytoplasmic transport	RBM4	IDA		Human	PMID:17284590
Biological Process	GO:0046822	regulation of nucleocytoplasmic transport	Rbm4	IDA		Mouse	MGI:MGI:4436983|PMID:19801630
Biological Process	GO:0046685	response to arsenic-containing substance	RBM4	IDA		Human	PMID:17284590

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern