Comparative GO Graph (mouse, human)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RBX1
  • Mouse genes Rbx1-ps
  • Rat genes
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rbx1-ps

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0097602	cullin family protein binding	RBX1	IDA		Human	PMID:10230407
Molecular Function	GO:0097602	cullin family protein binding	RBX1	IPI	UniProtKB:Q13618	Human	PMID:14528312
Molecular Function	GO:0060090	molecular adaptor activity	RBX1	EXP		Human	PMID:11961546
Molecular Function	GO:0061663	NEDD8 ligase activity	RBX1	IDA		Human	PMID:19250909
Molecular Function	GO:0005515	protein binding	RBX1	IPI	UniProtKB:Q13616	Human	PMID:11961546
Molecular Function	GO:0005515	protein binding	RBX1	IPI	UniProtKB:Q13616	Human	PMID:12504026
Molecular Function	GO:0005515	protein binding	RBX1	IPI	UniProtKB:Q13616	Human	PMID:12609982
Molecular Function	GO:0005515	protein binding	RBX1	IPI	UniProtKB:Q13620	Human	PMID:12609982
Molecular Function	GO:0005515	protein binding	RBX1	IPI	UniProtKB:Q13617	Human	PMID:15601820
Molecular Function	GO:0005515	protein binding	RBX1	IPI	UniProtKB:Q13617	Human	PMID:17183367
Molecular Function	GO:0005515	protein binding	RBX1	IPI	UniProtKB:Q13309	Human	PMID:18239684
Molecular Function	GO:0005515	protein binding	RBX1	IPI	UniProtKB:Q13616	Human	PMID:18805092
Molecular Function	GO:0005515	protein binding	RBX1	IPI	UniProtKB:Q93034	Human	PMID:18805092
Molecular Function	GO:0005515	protein binding	RBX1	IPI	UniProtKB:Q96GG9	Human	PMID:18826954
Molecular Function	GO:0005515	protein binding	RBX1	IPI	UniProtKB:P61081	Human	PMID:19250909
Molecular Function	GO:0005515	protein binding	RBX1	IPI	UniProtKB:Q13617	Human	PMID:19327355
Molecular Function	GO:0005515	protein binding	RBX1	IPI	UniProtKB:P61081	Human	PMID:19549727
Molecular Function	GO:0005515	protein binding	RBX1	IPI	UniProtKB:Q13616	Human	PMID:20399188
Molecular Function	GO:0005515	protein binding	RBX1	IPI	UniProtKB:P61081	Human	PMID:21765416
Molecular Function	GO:0005515	protein binding	RBX1	IPI	UniProtKB:Q13616	Human	PMID:21765416
Molecular Function	GO:0005515	protein binding	RBX1	IPI	UniProtKB:Q13616	Human	PMID:22660580
Molecular Function	GO:0005515	protein binding	RBX1	IPI	UniProtKB:Q13620	Human	PMID:23238014
Molecular Function	GO:0005515	protein binding	RBX1	IPI	UniProtKB:P58004	Human	PMID:23274085
Molecular Function	GO:0005515	protein binding	RBX1	IPI	UniProtKB:P40337,UniProtKB:Q13617	Human	PMID:23401859
Molecular Function	GO:0005515	protein binding	RBX1	IPI	UniProtKB:P40337,UniProtKB:Q13617,UniProtKB:Q15370,UniProtKB:Q16665	Human	PMID:23401859
Molecular Function	GO:0005515	protein binding	RBX1	IPI	UniProtKB:P40337,UniProtKB:Q13617,UniProtKB:Q16665	Human	PMID:23401859
Molecular Function	GO:0005515	protein binding	RBX1	IPI	UniProtKB:P40337,UniProtKB:Q13617,UniProtKB:Q16665,UniProtKB:Q16665	Human	PMID:23401859
Molecular Function	GO:0005515	protein binding	RBX1	IPI	UniProtKB:P40337,UniProtKB:Q13617,UniProtKB:Q99814	Human	PMID:23401859
Molecular Function	GO:0005515	protein binding	RBX1	IPI	UniProtKB:Q13617	Human	PMID:23401859
Molecular Function	GO:0005515	protein binding	RBX1	IPI	UniProtKB:Q96GG9	Human	PMID:24192928
Molecular Function	GO:0005515	protein binding	RBX1	IPI	UniProtKB:Q9BTE7	Human	PMID:24192928
Molecular Function	GO:0005515	protein binding	RBX1	IPI	UniProtKB:Q8IWT3	Human	PMID:24793696
Molecular Function	GO:0005515	protein binding	RBX1	IPI	UniProtKB:Q13616	Human	PMID:24949976
Molecular Function	GO:0005515	protein binding	RBX1	IPI	UniProtKB:Q86V97	Human	PMID:25684205
Molecular Function	GO:0005515	protein binding	RBX1	IPI	UniProtKB:Q8WVZ9	Human	PMID:25684205
Molecular Function	GO:0005515	protein binding	RBX1	IPI	UniProtKB:Q13620	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	RBX1	IPI	UniProtKB:Q6PH85	Human	PMID:26906416
Molecular Function	GO:0005515	protein binding	RBX1	IPI	UniProtKB:Q8IWE4	Human	PMID:26906416
Molecular Function	GO:0005515	protein binding	RBX1	IPI	UniProtKB:Q92564	Human	PMID:26906416
Molecular Function	GO:0005515	protein binding	RBX1	IPI	UniProtKB:Q96GG9	Human	PMID:26906416
Molecular Function	GO:0005515	protein binding	RBX1	IPI	UniProtKB:Q9BTE7	Human	PMID:26906416
Molecular Function	GO:0005515	protein binding	RBX1	IPI	UniProtKB:P63208,UniProtKB:Q04721,UniProtKB:Q13616,UniProtKB:Q969H0	Human	PMID:29149593
Molecular Function	GO:0005515	protein binding	RBX1	IPI	UniProtKB:P58004	Human	PMID:29294217
Molecular Function	GO:0005515	protein binding	RBX1	IPI	UniProtKB:Q13620	Human	PMID:30945288
Molecular Function	GO:0005515	protein binding	RBX1	IPI	UniProtKB:P59991	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RBX1	IPI	UniProtKB:P61081	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RBX1	IPI	UniProtKB:Q13617	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RBX1	IPI	UniProtKB:Q92990	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RBX1	IPI	UniProtKB:Q9BYU1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RBX1	IPI	UniProtKB:Q13616	Human	PMID:32726803
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	RBX1	IPI	UniProtKB:P05412	Human	PMID:14739464
Molecular Function	GO:0061630	ubiquitin protein ligase activity	RBX1	IDA		Human	PMID:10230407
Molecular Function	GO:0061630	ubiquitin protein ligase activity	RBX1	IDA		Human	PMID:11027288
Molecular Function	GO:0061630	ubiquitin protein ligase activity	RBX1	IDA		Human	PMID:16482215
Molecular Function	GO:0061630	ubiquitin protein ligase activity	RBX1	IDA		Human	PMID:17636018
Molecular Function	GO:0061630	ubiquitin protein ligase activity	RBX1	IDA		Human	PMID:20870715
Molecular Function	GO:0061630	ubiquitin protein ligase activity	RBX1	IDA		Human	PMID:22405651
Molecular Function	GO:0061630	ubiquitin protein ligase activity	RBX1	IDA		Human	PMID:27626656
Molecular Function	GO:0031625	ubiquitin protein ligase binding	RBX1	IDA		Human	PMID:17636018
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	RBX1	IDA		Human	PMID:15983046
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	RBX1	IDA		Human	PMID:20389280
Molecular Function	GO:0034450	ubiquitin-ubiquitin ligase activity	RBX1	IDA		Human	PMID:10230407
Cellular Component	GO:0031462	Cul2-RING ubiquitin ligase complex	RBX1	IDA		Human	PMID:17636018
Cellular Component	GO:0031463	Cul3-RING ubiquitin ligase complex	RBX1	IDA		Human	PMID:14528312
Cellular Component	GO:0031463	Cul3-RING ubiquitin ligase complex	RBX1	IDA		Human	PMID:15983046
Cellular Component	GO:0031463	Cul3-RING ubiquitin ligase complex	RBX1	IDA		Human	PMID:17543862
Cellular Component	GO:0031463	Cul3-RING ubiquitin ligase complex	RBX1	IDA		Human	PMID:20389280
Cellular Component	GO:0031463	Cul3-RING ubiquitin ligase complex	RBX1	IDA		Human	PMID:22358839
Cellular Component	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex	RBX1	EXP		Human	PMID:22118460
Cellular Component	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex	RBX1	IDA		Human	PMID:12732143
Cellular Component	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex	RBX1	IDA		Human	PMID:14739464
Cellular Component	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex	RBX1	IDA		Human	PMID:17085480
Cellular Component	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex	RBX1	IDA		Human	PMID:18794347
Cellular Component	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex	RBX1	IDA		Human	PMID:20129063
Cellular Component	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex	RBX1	IDA		Human	PMID:20223979
Cellular Component	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex	RBX1	IDA		Human	PMID:18794347
Cellular Component	GO:0031466	Cul5-RING ubiquitin ligase complex	RBX1	IDA		Human	PMID:17636018
Cellular Component	GO:0031467	Cul7-RING ubiquitin ligase complex	RBX1	IDA		Human	PMID:18498745
Cellular Component	GO:0031461	cullin-RING ubiquitin ligase complex	RBX1	IDA		Human	PMID:22405651
Cellular Component	GO:0005654	nucleoplasm	RBX1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	RBX1	IDA		Human	PMID:11027288
Cellular Component	GO:0019005	SCF ubiquitin ligase complex	RBX1	IDA		Human	PMID:11956208
Cellular Component	GO:0019005	SCF ubiquitin ligase complex	RBX1	IDA		Human	PMID:15103331
Cellular Component	GO:0019005	SCF ubiquitin ligase complex	RBX1	IDA		Human	PMID:21572392
Cellular Component	GO:0019005	SCF ubiquitin ligase complex	RBX1	IDA		Human	PMID:23263282
Cellular Component	GO:0019005	SCF ubiquitin ligase complex	RBX1	IDA		Human	PMID:25585578
Biological Process	GO:0034644	cellular response to UV	RBX1	EXP		Human	PMID:22118460
Biological Process	GO:0006974	DNA damage response	RBX1	EXP		Human	PMID:22118460
Biological Process	GO:0032480	negative regulation of type I interferon production	RBX1	IDA		Human	PMID:36394357
Biological Process	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	RBX1	IPI	UniProtKB:Q7L5Y6	Human	PMID:14739464
Biological Process	GO:1902499	positive regulation of protein autoubiquitination	RBX1	IMP		Human	PMID:14528312
Biological Process	GO:0045732	positive regulation of protein catabolic process	RBX1	IDA		Human	PMID:11027288
Biological Process	GO:0045732	positive regulation of protein catabolic process	RBX1	IDA		Human	PMID:16482215
Biological Process	GO:0045732	positive regulation of protein catabolic process	RBX1	IDA		Human	PMID:27626656
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	RBX1	IDA		Human	PMID:20389280
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	RBX1	IDA		Human	PMID:34480022
Biological Process	GO:0070936	protein K48-linked ubiquitination	RBX1	IDA		Human	PMID:15103331
Biological Process	GO:0070936	protein K48-linked ubiquitination	RBX1	IDA		Human	PMID:25684205
Biological Process	GO:0006513	protein monoubiquitination	RBX1	IDA		Human	PMID:22358839
Biological Process	GO:0045116	protein neddylation	RBX1	IDA		Human	PMID:19250909
Biological Process	GO:0000209	protein polyubiquitination	RBX1	IDA		Human	PMID:14528312
Biological Process	GO:0016567	protein ubiquitination	RBX1	IPI	UniProtKB:Q7L5Y6	Human	PMID:14739464
Biological Process	GO:0016567	protein ubiquitination	RBX1	IDA		Human	PMID:15103331
Biological Process	GO:0016567	protein ubiquitination	RBX1	IDA		Human	PMID:17543862
Biological Process	GO:0016567	protein ubiquitination	RBX1	IDA		Human	PMID:20389280
Biological Process	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	RBX1	IDA		Human	PMID:15103331
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	RBX1	IDA		Human	PMID:17636018

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern