Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RCAN1
  • Mouse genes Rcan1
  • Rat genes Rcan1
  • Zfish genes rcan1a,rcan1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rcan1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	RCAN1	IPI	UniProtKB:P63098|UniProtKB:Q08209	Human	PMID:12809556
Molecular Function	GO:0005515	protein binding	Rcan1	IPI	UniProtKB:Q61214	Mouse	MGI:MGI:5297623|PMID:21965663
Molecular Function	GO:0005515	protein binding	Rcan1	IPI	UniProtKB:P35922	Mouse	MGI:MGI:5441164|PMID:22863780
Molecular Function	GO:0005515	protein binding	Rcan1	IPI	UniProtKB:P63328	Mouse	MGI:MGI:6148615|PMID:12809556
Cellular Component	GO:0005737	cytoplasm	Rcan1	IDA		Mouse	PMID:10722714
Cellular Component	GO:0005634	nucleus	Rcan1	IDA		Mouse	PMID:10722714
Biological Process	GO:0033173	calcineurin-NFAT signaling cascade	Rcan1	IGI	MGI:MGI:1858219	Mouse	PMID:16648267
Biological Process	GO:0033173	calcineurin-NFAT signaling cascade	Rcan1	IMP	MGI:MGI:3641540	Mouse	PMID:16648267
Biological Process	GO:0031987	locomotion involved in locomotory behavior	Rcan1	IGI	MGI:MGI:1858219	Mouse	PMID:16648267
Biological Process	GO:0070885	negative regulation of calcineurin-NFAT signaling cascade	RCAN1	IMP		Human	PMID:12809556
Biological Process	GO:0051151	negative regulation of smooth muscle cell differentiation	Rcan1	IDA		Rat	PMID:15148306|RGD:1581653
Biological Process	GO:0043666	regulation of phosphoprotein phosphatase activity	Rcan1	IDA		Mouse	PMID:16024798
Biological Process	GO:0043627	response to estrogen	Rcan1	IMP		Rat	PMID:15899894|RGD:1581475
Biological Process	GO:0002931	response to ischemia	Rcan1	IMP	MGI:MGI:3641540	Mouse	PMID:16648267
Biological Process	GO:0009612	response to mechanical stimulus	Rcan1	IEP		Rat	PMID:12124198|RGD:625605
Biological Process	GO:0006979	response to oxidative stress	Rcan1	IGI	MGI:MGI:1858219	Mouse	PMID:16648267
Biological Process	GO:0006950	response to stress	Rcan1	IGI	MGI:MGI:1858219	Mouse	PMID:16648267
Biological Process	GO:0006950	response to stress	Rcan1	IMP	MGI:MGI:3641540	Mouse	PMID:16648267
Biological Process	GO:0007614	short-term memory	Rcan1	IGI	MGI:MGI:1858219	Mouse	PMID:16648267
Biological Process	GO:0048741	skeletal muscle fiber development	Rcan1	IDA		Mouse	PMID:16024798
Biological Process	GO:0007519	skeletal muscle tissue development	Rcan1	IEP		Rat	PMID:15219871|RGD:1304341
Biological Process	GO:0002040	sprouting angiogenesis	rcan1a	IMP	ZFIN:ZDB-MRPHLNO-170911-1	Zfish	PMID:28271280

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern