Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RCC1
  • Mouse genes Rcc1
  • Rat genes Rcc1
  • Zfish genes rcc1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rcc1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	RCC1	IDA		Human	PMID:2677018
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	RCC1	IMP		Human	PMID:11336674
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	RCC1	IDA		Human	PMID:1944575
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	Rcc1	IDA		Mouse	PMID:18347012
Molecular Function	GO:0042393	histone binding	RCC1	IDA		Human	PMID:11375490
Molecular Function	GO:0031492	nucleosomal DNA binding	RCC1	IDA		Human	PMID:17435751
Molecular Function	GO:0031491	nucleosome binding	RCC1	IMP		Human	PMID:20347844
Molecular Function	GO:0005515	protein binding	RCC1	IPI	UniProtKB:P62826	Human	PMID:11336674
Molecular Function	GO:0005515	protein binding	RCC1	IPI	UniProtKB:Q9H6Z4	Human	PMID:11932251
Molecular Function	GO:0005515	protein binding	RCC1	IPI	UniProtKB:P32121	Human	PMID:16820410
Molecular Function	GO:0005515	protein binding	RCC1	IPI	UniProtKB:P62826	Human	PMID:18617507
Molecular Function	GO:0005515	protein binding	RCC1	IPI	UniProtKB:P62826	Human	PMID:1961752
Molecular Function	GO:0005515	protein binding	RCC1	IPI	UniProtKB:Q9BV86	Human	PMID:20668449
Molecular Function	GO:0005515	protein binding	RCC1	IPI	UniProtKB:P02281	Human	PMID:20739938
Molecular Function	GO:0005515	protein binding	RCC1	IPI	UniProtKB:P62826	Human	PMID:29040603
Molecular Function	GO:0005515	protein binding	RCC1	IPI	UniProtKB:P62826	Human	PMID:29997244
Molecular Function	GO:0005515	protein binding	RCC1	IPI	UniProtKB:P62826	Human	PMID:31467278
Molecular Function	GO:0005515	protein binding	RCC1	IPI	UniProtKB:O00505	Human	PMID:34564892
Molecular Function	GO:0005515	protein binding	RCC1	IPI	UniProtKB:P43487	Human	PMID:7616957
Molecular Function	GO:0005515	protein binding	RCC1	IPI	UniProtKB:Q9H6Z4-2	Human	PMID:9637251
Molecular Function	GO:0046982	protein heterodimerization activity	RCC1	IPI	UniProtKB:P62826	Human	PMID:11336674
Molecular Function	GO:0031267	small GTPase binding	RCC1	IDA		Human	PMID:11336674
Molecular Function	GO:0043199	sulfate binding	RCC1	IDA		Human	PMID:11336674
Cellular Component	GO:0000785	chromatin	RCC1	IDA		Human	PMID:12121620
Cellular Component	GO:0000785	chromatin	RCC1	IDA		Human	PMID:15014043
Cellular Component	GO:0000794	condensed nuclear chromosome	RCC1	IDA		Human	PMID:15014043
Cellular Component	GO:0005737	cytoplasm	RCC1	IDA		Human	PMID:17435751
Cellular Component	GO:0005654	nucleoplasm	RCC1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	RCC1	IDA		Human	PMID:17435751
Cellular Component	GO:0005634	nucleus	RCC1	HDA		Human	PMID:21630459
Cellular Component	GO:0032991	protein-containing complex	RCC1	IDA		Human	PMID:11336674
Biological Process	GO:0007059	chromosome segregation	RCC1	IMP		Human	PMID:17435751
Biological Process	GO:0000082	G1/S transition of mitotic cell cycle	RCC1	IMP		Human	PMID:3678831
Biological Process	GO:0007052	mitotic spindle organization	RCC1	IDA		Human	PMID:15014043
Biological Process	GO:0007088	regulation of mitotic nuclear division	RCC1	IDA		Human	PMID:15014043
Biological Process	GO:0051225	spindle assembly	RCC1	IMP		Human	PMID:17435751

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern