Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RECQL5
  • Mouse genes Recql5
  • Rat genes Recql5
  • Zfish genes recql5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Recql5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003678	DNA helicase activity	RECQL5	IDA		Human	PMID:22013166
Molecular Function	GO:0008047	enzyme activator activity	RECQL5	IDA		Human	PMID:18003859
Molecular Function	GO:0004386	helicase activity	RECQL5	IDA		Human	PMID:18003859
Molecular Function	GO:0140678	molecular function inhibitor activity	RECQL5	IDA		Human	PMID:18003859
Molecular Function	GO:0000993	RNA polymerase II complex binding	RECQL5	IDA		Human	PMID:23748380
Cellular Component	GO:0005829	cytosol	RECQL5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	RECQL5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	RECQL5	IDA		Human	PMID:22013166
Cellular Component	GO:0005657	replication fork	RECQL5	IDA		Human	PMID:18003859
Cellular Component	GO:0097550	transcription preinitiation complex	RECQL5	IDA		Human	PMID:22231121
Biological Process	GO:0072757	cellular response to camptothecin	Recql5	IMP		Mouse	PMID:25520194
Biological Process	GO:0072757	cellular response to camptothecin	Recql5	IGI	MGI:MGI:2448558	Mouse	PMID:25520194
Biological Process	GO:1901655	cellular response to ketone	Recql5	IMP		Mouse	PMID:25520194
Biological Process	GO:1901655	cellular response to ketone	Recql5	IGI	MGI:MGI:2448558	Mouse	PMID:25520194
Biological Process	GO:0071407	cellular response to organic cyclic compound	Recql5	IMP		Mouse	PMID:25520194
Biological Process	GO:0071407	cellular response to organic cyclic compound	Recql5	IGI	MGI:MGI:2448558	Mouse	PMID:25520194
Biological Process	GO:0071417	cellular response to organonitrogen compound	Recql5	IMP		Mouse	PMID:25520194
Biological Process	GO:0071417	cellular response to organonitrogen compound	Recql5	IGI	MGI:MGI:2448558	Mouse	PMID:25520194
Biological Process	GO:0071466	cellular response to xenobiotic stimulus	Recql5	IGI	MGI:MGI:2448558	Mouse	PMID:25520194
Biological Process	GO:0071466	cellular response to xenobiotic stimulus	Recql5	IMP		Mouse	PMID:25520194
Biological Process	GO:0051304	chromosome separation	RECQL5	IMP		Human	PMID:22013166
Biological Process	GO:0006281	DNA repair	RECQL5	IMP		Human	PMID:22973052
Biological Process	GO:0006260	DNA replication	RECQL5	IMP		Human	PMID:22013166
Biological Process	GO:0000278	mitotic cell cycle	RECQL5	IMP		Human	PMID:22013166
Biological Process	GO:1990506	mitotic DNA-templated DNA replication	RECQL5	IDA		Human	PMID:28575661
Biological Process	GO:2000042	negative regulation of double-strand break repair via homologous recombination	Recql5	IGI	MGI:MGI:2448558	Mouse	PMID:25520194
Biological Process	GO:0045950	negative regulation of mitotic recombination	recql5	IMP		Zfish	PMID:17483412
Biological Process	GO:0034244	negative regulation of transcription elongation by RNA polymerase II	RECQL5	IDA		Human	PMID:23748380
Biological Process	GO:1990414	replication-born double-strand break repair via sister chromatid exchange	Recql5	IMP		Mouse	PMID:25520194

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern