Comparative GO Graph (mouse, human)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes REG1A,REG1B
  • Mouse genes Reg2
  • Rat genes
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Reg2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008083	growth factor activity	REG1A	IDA		Human	PMID:10526060
Molecular Function	GO:0140678	molecular function inhibitor activity	REG1A	IDA		Human	PMID:1397886
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Reg2	HDA		Mouse	MGI:MGI:6201853|PMID:28071719
Cellular Component	GO:0070062	extracellular exosome	REG1A	HDA		Human	PMID:23533145
Cellular Component	GO:0070062	extracellular exosome	REG1B	HDA		Human	PMID:23533145
Biological Process	GO:0042552	myelination	Reg2	IMP	MGI:MGI:3812476	Mouse	PMID:18678917
Biological Process	GO:0001967	suckling behavior	Reg2	IMP	MGI:MGI:3812476	Mouse	PMID:18678917

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern