Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes REG3A,REG3G
  • Mouse genes Reg3b
  • Rat genes Reg3b
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Reg3b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019838	growth factor binding	Reg3b	IPI	RGD:3552	Rat	PMID:10662590|RGD:10044032
Molecular Function	GO:0042802	identical protein binding	REG3A	IPI	UniProtKB:Q06141	Human	PMID:24256734
Molecular Function	GO:0042802	identical protein binding	Reg3b	IPI	RGD:3254	Rat	PMID:11278730|RGD:9831423
Molecular Function	GO:0070492	oligosaccharide binding	REG3G	IDA		Human	PMID:16931762
Molecular Function	GO:0042834	peptidoglycan binding	REG3G	IDA		Human	PMID:16931762
Molecular Function	GO:0005515	protein binding	REG3A	IPI	UniProtKB:Q99750	Human	PMID:25416956
Cellular Component	GO:0045177	apical part of cell	Reg3b	IDA		Rat	PMID:12764608|RGD:9831428
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Reg3b	HDA		Mouse	MGI:MGI:6201853|PMID:28071719
Cellular Component	GO:0005737	cytoplasm	Reg3b	IDA		Rat	PMID:21093549|RGD:9831382
Cellular Component	GO:0005615	extracellular space	Reg3b	IDA		Rat	PMID:11066135|RGD:9831384
Cellular Component	GO:0032991	protein-containing complex	Reg3b	IDA		Rat	PMID:11278730|RGD:9831423
Cellular Component	GO:0042588	zymogen granule	Reg3b	IDA		Rat	PMID:12764608|RGD:9831428
Biological Process	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide	REG3G	IDA		Human	PMID:16931762
Biological Process	GO:0044278	cell wall disruption in another organism	REG3G	IDA		Human	PMID:16931762
Biological Process	GO:1903577	cellular response to L-arginine	Reg3b	IEP		Rat	PMID:10630385|RGD:9831424
Biological Process	GO:0071356	cellular response to tumor necrosis factor	Reg3b	IEP		Rat	PMID:10982776|RGD:9831402
Biological Process	GO:0071466	cellular response to xenobiotic stimulus	Reg3b	IEP		Rat	PMID:11854617|RGD:9831383
Biological Process	GO:0050829	defense response to Gram-negative bacterium	Reg3b	IDA		Mouse	MGI:MGI:5488881|PMID:21694778
Biological Process	GO:0050830	defense response to Gram-positive bacterium	Reg3b	IDA		Mouse	MGI:MGI:5488881|PMID:21694778
Biological Process	GO:0044849	estrous cycle	Reg3b	IEP		Rat	PMID:7758828|RGD:9831431
Biological Process	GO:0007565	female pregnancy	Reg3b	IEP		Rat	PMID:7758828|RGD:9831431
Biological Process	GO:0007494	midgut development	Reg3b	IEP		Rat	PMID:7720628|RGD:9850133
Biological Process	GO:0043066	negative regulation of apoptotic process	Reg3b	IEP		Rat	PMID:10630385|RGD:9831424
Biological Process	GO:1900408	negative regulation of cellular response to oxidative stress	Reg3b	IDA		Rat	PMID:21643999|RGD:9831400
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	Reg3b	IDA		Rat	PMID:21643999|RGD:9831400
Biological Process	GO:0008284	positive regulation of cell population proliferation	Reg3b	IMP		Rat	PMID:24055447|RGD:9850134
Biological Process	GO:0001934	positive regulation of protein phosphorylation	Reg3b	IDA		Rat	PMID:21643999|RGD:9831400
Biological Process	GO:0009617	response to bacterium	Reg3b	IEP		Mouse	PMID:23012479
Biological Process	GO:0032355	response to estradiol	Reg3b	IEP		Rat	PMID:7758828|RGD:9831431
Biological Process	GO:0031667	response to nutrient levels	Reg3b	IEP		Rat	PMID:7481529|RGD:9831398
Biological Process	GO:0043434	response to peptide hormone	Reg3b	IEP		Rat	PMID:7720628|RGD:9850133
Biological Process	GO:0042594	response to starvation	Reg3b	IEP		Rat	PMID:8238345|RGD:729577

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern