Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes REG3G
  • Mouse genes Reg3g
  • Rat genes Reg3g
  • Zfish genes si:ch211-125e6.14
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Reg3g

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005179	hormone activity	Reg3g	IDA		Mouse	PMID:28811323
Molecular Function	GO:0005179	hormone activity	Reg3g	IDA		Mouse	PMID:27830702
Molecular Function	GO:0070492	oligosaccharide binding	REG3G	IDA		Human	PMID:16931762
Molecular Function	GO:0070492	oligosaccharide binding	Reg3g	IDA		Mouse	MGI:MGI:5897756|PMID:16931762
Molecular Function	GO:0042834	peptidoglycan binding	REG3G	IDA		Human	PMID:16931762
Molecular Function	GO:0042834	peptidoglycan binding	Reg3g	IDA		Mouse	MGI:MGI:5897756|PMID:16931762
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Reg3g	HDA		Mouse	MGI:MGI:6201853|PMID:28071719
Cellular Component	GO:0005615	extracellular space	Reg3g	IDA		Mouse	MGI:MGI:5897756|PMID:16931762
Cellular Component	GO:0005615	extracellular space	Reg3g	IDA		Mouse	PMID:28811323
Cellular Component	GO:0005615	extracellular space	Reg3g	IDA		Mouse	PMID:27830702
Cellular Component	GO:0030141	secretory granule	Reg3g	IDA		Mouse	MGI:MGI:5897756|PMID:16931762
Biological Process	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide	REG3G	IDA		Human	PMID:16931762
Biological Process	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide	Reg3g	IDA		Mouse	MGI:MGI:5897756|PMID:16931762
Biological Process	GO:0044278	cell wall disruption in another organism	REG3G	IDA		Human	PMID:16931762
Biological Process	GO:0044278	cell wall disruption in another organism	Reg3g	IDA		Mouse	MGI:MGI:5897756|PMID:16931762
Biological Process	GO:0050829	defense response to Gram-negative bacterium	Reg3g	IDA		Mouse	MGI:MGI:5897756|PMID:16931762
Biological Process	GO:0050830	defense response to Gram-positive bacterium	Reg3g	IMP		Mouse	MGI:MGI:3760234|PMID:17635956
Biological Process	GO:0050830	defense response to Gram-positive bacterium	Reg3g	IDA		Mouse	MGI:MGI:5897756|PMID:16931762
Biological Process	GO:0050830	defense response to Gram-positive bacterium	Reg3g	IDA		Mouse	MGI:MGI:5488544|PMID:23401489
Biological Process	GO:0002755	MyD88-dependent toll-like receptor signaling pathway	Reg3g	IMP		Mouse	MGI:MGI:3760234|PMID:17635956
Biological Process	GO:0050728	negative regulation of inflammatory response	Reg3g	IDA		Mouse	PMID:28811323
Biological Process	GO:0106015	negative regulation of inflammatory response to wounding	Reg3g	IDA		Mouse	PMID:27830702
Biological Process	GO:0045617	negative regulation of keratinocyte differentiation	Reg3g	IDA		Mouse	MGI:MGI:5488867|PMID:22727489
Biological Process	GO:0010838	positive regulation of keratinocyte proliferation	Reg3g	IDA		Mouse	MGI:MGI:5488867|PMID:22727489
Biological Process	GO:0090303	positive regulation of wound healing	Reg3g	IDA		Mouse	MGI:MGI:5488867|PMID:22727489
Biological Process	GO:0009617	response to bacterium	Reg3g	IEP		Mouse	PMID:23012479

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern