Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RELB
  • Mouse genes Relb
  • Rat genes Relb
  • Zfish genes relb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Relb

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	Relb	IDA		Mouse	PMID:15944286
Molecular Function	GO:0003677	DNA binding	Relb	IDA		Rat	PMID:17250675|RGD:2302394
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Relb	IMP		Mouse	MGI:MGI:71960|PMID:8441398
Molecular Function	GO:0042802	identical protein binding	Relb	IPI	UniProtKB:Q04863	Mouse	MGI:MGI:5925443|PMID:16154093
Molecular Function	GO:0005515	protein binding	RELB	IPI	UniProtKB:P19838	Human	PMID:14743216
Molecular Function	GO:0005515	protein binding	RELB	IPI	UniProtKB:Q00653	Human	PMID:14743216
Molecular Function	GO:0005515	protein binding	RELB	IPI	UniProtKB:Q04206-2	Human	PMID:14743216
Molecular Function	GO:0005515	protein binding	RELB	IPI	UniProtKB:Q8N668	Human	PMID:15799966
Molecular Function	GO:0005515	protein binding	RELB	IPI	UniProtKB:P49841	Human	PMID:21217772
Molecular Function	GO:0005515	protein binding	RELB	IPI	UniProtKB:P19838	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	RELB	IPI	UniProtKB:P19838	Human	PMID:25609649
Molecular Function	GO:0005515	protein binding	RELB	IPI	UniProtKB:Q00653	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	RELB	IPI	UniProtKB:Q04206-2	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	RELB	IPI	UniProtKB:P19838	Human	PMID:35140242
Molecular Function	GO:0005515	protein binding	Relb	IPI	UniProtKB:Q9WTL8	Mouse	MGI:MGI:5574290|PMID:22894897
Molecular Function	GO:0005515	protein binding	Relb	IPI	UniProtKB:O54910|UniProtKB:P25799:PRO_0000030313|UniProtKB:Q9WTK5|UniProtKB:Q9Z1E3	Mouse	MGI:MGI:5449469|PMID:23086447
Molecular Function	GO:0005515	protein binding	Relb	IPI	UniProtKB:Q9WTK5	Mouse	MGI:MGI:4455093|PMID:20211142
Molecular Function	GO:0005515	protein binding	Relb	IPI	UniProtKB:P25963	Mouse	PMID:11931770
Molecular Function	GO:0005515	protein binding	Relb	IPI	PR:Q2TB02	Mouse	PMID:11931770
Molecular Function	GO:0019901	protein kinase binding	RELB	IPI	UniProtKB:Q9HC98	Human	PMID:20873783
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	RELB	IDA		Human	PMID:23729669
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Relb	IMP		Mouse	MGI:MGI:71960|PMID:8441398
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Relb	IDA		Mouse	MGI:MGI:5574290|PMID:22894897
Cellular Component	GO:0005813	centrosome	RELB	IDA		Human	PMID:20873783
Cellular Component	GO:0000785	chromatin	RELB	IDA		Human	PMID:23729669
Cellular Component	GO:0005829	cytosol	RELB	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	Relb	IDA		Mouse	PMID:11931770
Cellular Component	GO:0005654	nucleoplasm	RELB	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	RELB	IDA		Human	PMID:22065573
Cellular Component	GO:0005634	nucleus	Relb	IDA		Mouse	PMID:21874024
Cellular Component	GO:0005634	nucleus	Relb	IDA		Mouse	PMID:11931770
Cellular Component	GO:0005634	nucleus	Relb	IDA		Rat	PMID:17250675|RGD:2302394
Cellular Component	GO:0032991	protein-containing complex	RELB	IDA		Human	PMID:20873783
Cellular Component	GO:0045202	synapse	Relb	IDA		Mouse	PMID:22514330
Cellular Component	GO:0045202	synapse	Relb	IEP		Mouse	PMID:22514330
Cellular Component	GO:0017053	transcription repressor complex	RELB	IDA		Human	PMID:19158276
Biological Process	GO:0019882	antigen processing and presentation	Relb	IMP	MGI:MGI:2179544	Mouse	PMID:7845467
Biological Process	GO:0071470	cellular response to osmotic stress	Relb	IDA		Rat	PMID:16716309|RGD:7777165
Biological Process	GO:0032922	circadian regulation of gene expression	Relb	IMP		Mouse	MGI:MGI:5574290|PMID:22894897
Biological Process	GO:0030098	lymphocyte differentiation	RELB	IMP		Human	PMID:26385063
Biological Process	GO:0043011	myeloid dendritic cell differentiation	Relb	IMP	MGI:MGI:2179544	Mouse	PMID:14499111
Biological Process	GO:0043011	myeloid dendritic cell differentiation	Relb	IMP	MGI:MGI:2179544	Mouse	PMID:7845467
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Relb	IDA		Mouse	MGI:MGI:5574290|PMID:22894897
Biological Process	GO:0032688	negative regulation of interferon-beta production	RELB	IMP		Human	PMID:22065573
Biological Process	GO:0038061	NIK/NF-kappaB signaling	Relb	IDA		Mouse	PMID:23583643
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Relb	IMP		Mouse	MGI:MGI:71960|PMID:8441398
Biological Process	GO:0045063	T-helper 1 cell differentiation	Relb	IMP	MGI:MGI:2179545	Mouse	PMID:16081776
Biological Process	GO:0042088	T-helper 1 type immune response	Relb	IMP	MGI:MGI:2179544	Mouse	PMID:7845467

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern