Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RETN
  • Mouse genes Retn
  • Rat genes Retn
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Retn

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	RETN	IPI	UniProtKB:O00155	Human	PMID:32296183
Cellular Component	GO:0070062	extracellular exosome	RETN	HDA		Human	PMID:23533145
Cellular Component	GO:0005576	extracellular region	Retn	IDA		Mouse	PMID:11209052
Cellular Component	GO:0005615	extracellular space	Retn	IDA		Mouse	PMID:17693256
Cellular Component	GO:0005615	extracellular space	Retn	IDA		Rat	PMID:16125524|RGD:1624969
Cellular Component	GO:0005634	nucleus	Retn	IDA		Rat	PMID:14644422|RGD:1624972
Biological Process	GO:0007568	aging	Retn	IEP		Rat	PMID:19154953|RGD:7207255
Biological Process	GO:0045444	fat cell differentiation	Retn	IMP		Rat	PMID:15191360|RGD:1624971
Biological Process	GO:2000252	negative regulation of feeding behavior	Retn	IDA		Rat	PMID:19183337|RGD:7207254
Biological Process	GO:0010714	positive regulation of collagen metabolic process	Retn	IMP		Rat	PMID:20795947|RGD:7207234
Biological Process	GO:2000872	positive regulation of progesterone secretion	Retn	IDA		Rat	PMID:21239528|RGD:7207233
Biological Process	GO:0014911	positive regulation of smooth muscle cell migration	Retn	IMP		Rat	PMID:20795947|RGD:7207234
Biological Process	GO:0048661	positive regulation of smooth muscle cell proliferation	Retn	IMP		Rat	PMID:20795947|RGD:7207234
Biological Process	GO:0050806	positive regulation of synaptic transmission	Retn	IDA		Rat	PMID:22702339|RGD:7207221
Biological Process	GO:0032868	response to insulin	Retn	IMP		Rat	PMID:15191360|RGD:1624971
Biological Process	GO:0009612	response to mechanical stimulus	Retn	IEP		Rat	PMID:20310085|RGD:7207250

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern