Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RFPL1,RFPL2,RFPL3,RFPL4A,RFPL4AL1
  • Mouse genes Rfpl4
  • Rat genes Rfpl4a
  • Zfish genes cabz01076234.2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rfpl4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	RFPL4A	IPI	UniProtKB:Q8N5I3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RFPL3	IPI	UniProtKB:Q7KZS0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RFPL3	IPI	UniProtKB:Q8TBB1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RFPL3	IPI	UniProtKB:P47813	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RFPL3	IPI	UniProtKB:Q16082	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RFPL3	IPI	UniProtKB:Q6ZUJ4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RFPL3	IPI	UniProtKB:Q8ND83	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RFPL3	IPI	UniProtKB:Q8WVV4-1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RFPL3	IPI	UniProtKB:Q92546	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RFPL3	IPI	UniProtKB:Q96D03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RFPL3	IPI	UniProtKB:Q9NQP4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Rfpl4	IPI	PR:P24860	Mouse	PMID:12525704
Molecular Function	GO:0005515	protein binding	Rfpl4	IPI	PR:Q9Z255	Mouse	PMID:12525704
Cellular Component	GO:0005737	cytoplasm	RFPL1	IDA		Human	PMID:20725088
Cellular Component	GO:0005737	cytoplasm	Rfpl4	IDA		Mouse	PMID:12525704
Cellular Component	GO:0001674	female germ cell nucleus	Rfpl4	IDA		Mouse	PMID:12525704
Biological Process	GO:0051782	negative regulation of cell division	RFPL1	IDA		Human	PMID:20725088
Biological Process	GO:0008285	negative regulation of cell population proliferation	RFPL1	IDA		Human	PMID:20725088
Biological Process	GO:0010972	negative regulation of G2/M transition of mitotic cell cycle	RFPL1	IDA		Human	PMID:20725088
Biological Process	GO:0045930	negative regulation of mitotic cell cycle	RFPL1	IDA		Human	PMID:20725088
Biological Process	GO:0043065	positive regulation of apoptotic process	RFPL1	IDA		Human	PMID:20725088
Biological Process	GO:2001272	positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis	RFPL1	IMP		Human	PMID:20725088
Biological Process	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	RFPL1	IMP		Human	PMID:20725088

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern